First experience of laser ablation for the treatment of nodular/multinodular non-toxic goiter at the russian university of medicine
E. N. Prazdnikov,
F. E. Rahimov,
M. M. Trandofilov,
V. V. Reznichenko,
S. E. Ovcharov,
V. S. Vakhromkin https://doi.org/10.17238/2072-3180-2025-1-127-132
Abstract
Introduction. This article presents the first experience of treatment and observation of nodular/multinodular nontoxic goiter. In addition to presenting the clinical observation, the article discusses the advantages of laser ablation, as well as the advantages of LA compared to other known treatment methods.
The purpose of the study. To evaluate the effectiveness of laser ablation for the treatment of nodular/multi-nodular non-toxic goiter
Materials and methods of research. The study was conducted on the basis of the Russian University Clinic. The Elesta Echolaser X4 device was used to evaluate the effectiveness of laser ablation. A clinical case of the method was analyzed. The assessment included changes in nodule volume, vascularization, and recovery dynamics in patients.
Treatment results. Patient F., 66 years old, with a 1,7 x 1,5 mm node after laser ablation showed a 61,8 % decrease in node volume after 6 months, with no vascularization according to dopplerography.
Conclusion. Laser ablation is an effective and safe method of treating nodular and multi-nodular non-toxic goiter. Its advantages include minimal injury, reduced recovery time, and the absence of significant cosmetic defects. This method may be the preferred choice for patients seeking to avoid radical surgical interventions.
About the Authors
E. N. Prazdnikov
FSBEI HE "Russian University of Medicine (RUM)" of the Ministry of Healthcare of the Russian Federation
Russian Federation
Russian Federation
Prazdnikov Eric Narimanovich, Doctor of Medical Sciences, Professor, Head of the Department of Operative Surgery and Topographic Anatomy
111398, Kuskovskaya 1A str., building 4, Moscow
F. E. Rahimov
FSBEI HE "Russian University of Medicine (RUM)" of the Ministry of Healthcare of the Russian Federation
Russian Federation
Russian Federation
Rahimov Farid Emin ogly, postgraduate student of the Department of Operative Surgery and Topographic Anatomy
111398, Kuskovskaya 1A str., building 4, Moscow
M. M. Trandofilov
FSBEI HE "Russian University of Medicine (RUM)" of the Ministry of Healthcare of the Russian Federation
Russian Federation
Russian Federation
Trandofilov Mikhail Mikhailovic, Doctor of Medical Sciences, Professor of the Department of Operative Surgery and Topographic Anatomy
111398, Kuskovskaya 1A str., building 4, Moscow
V. V. Reznichenko
FSBEI HE "Russian University of Medicine (RUM)" of the Ministry of Healthcare of the Russian Federation
Russian Federation
Russian Federation
Reznichenko Vitaly Vladimirovich, assistant of the Department of Operative Surgery and Topographic Anatomy
111398, Kuskovskaya 1A str., building 4, Moscow
S. E. Ovcharov
FSBEI HE "Russian University of Medicine (RUM)" of the Ministry of Healthcare of the Russian Federation
Russian Federation
Russian Federation
Ovcharov Sergey Eduardovich, candidate of Medical Sciences, Associate Professor, Head of the Academic Department of the Department of Operative Surgery and Topographic Anatomy
111398, Kuskovskaya 1A str., building 4, Moscow
V. S. Vakhromkin
FSBEI HE "Russian University of Medicine (RUM)" of the Ministry of Healthcare of the Russian Federation
Russian Federation
Russian Federation
Vakhromkin Vladimir Sergeevich, assistant of the Department of Operative Surgery and Topographic Anatomy
111398, Kuskovskaya 1A str., building 4, Moscow
References
1. Kachko V.A., Semkina G.V., Platonova N.M., Vanushko V.E., Abrosimov A.Yu. Diagnosis of thyroid neoplasms. Endocrine surgery, 2018, № 12(3), рр. 109–127. (In Russ.)
2. Verevkina N.A., Panchenkov D.N., Ivanov Yu.V., Soloviev N.A., and Silaev M.A. Radiofrequency ablation in the treatment of thyroid nodules in elderly patients. Doctor.Ru, 2015, № 1, pp. 53–56. (In Russ.)
3. Thomas J., Ledger G.A., Haertling T. Effects of Ultrasound-Guided Laser Ablation Therapy on Symptomatic Benign Thyroid Nodules, Using EchoLaser – Results of a Pilot Study in the United States. Endocr Pract., 2023, Dec; № 29(12), рр. 942–947.
4. Uspenskaya A.A., Chernikov R.A., Vorobyov S.L., Sleptsov I.V., Semenov A.A., Chinchuk I.K., Makarin V.A., Kulyash A.G., Timofeeva N.I., Novokshonov K.Yu., Karelina Yu.V., Fedorov E.A., Fedotov Yu.N., Bubnov A.N. Autonomously functioning thyroid nodes (epidemiology, clinic, diagnosis). Bulletin of St. Petersburg University. Medicine, 2014, № 2, pp. 75–84. (In Russ.)
5. Beltsevich D.G., Vanushko V.E., Melnichenko G.A., Rumyantsev P.O., Fadeev V.V. “Russian Association of Endocrinologists” Clinical guidelines for diagnosis and treatment of (multi) nodular goiter in adults, 2016, pр. 8. (In Russ.)
6. Mauri G., Nicosia L., Della Vigna P., Varano G.M., Maiettini D., Bonomo G., Giuliano G., Orsi F., Solbiati L., De Fiori E., Papini E., Pacella C.M., Sconfienza L.M. Percutaneous laser ablation for benign and malignant thyroid diseases. Ultrasonography, 2019, Jan; № 38(1), рр. 25–36.
7. Sui WF, Li JY, Fu JH. Percutaneous laser ablation for benign thyroid nodules: a meta-analysis. Oncotarget, 2017, May; № 17;8, рр. 47).
8. Gambelunge G., Stefanetti E., Avania N., et al. “Long-term outcomes of laser ablation for benign thyroid nodules: A 10-year follow-up study in 171 patients.” Journal of the Endocrine Society, 2021.
9. Chai W., Zhao Q., Song H.et al. Treatment response and preliminary efficacy of hepatic tumour laser ablation under the guidance of percutaneous and endoscopic ultrasonography. World Journal of Surgical Oncology, 2019, № 17, рр. 133.
10. Pacella C.M., Mauri G., Achille G., Barbaro D., Bizzarri G., De Feo P., Di Stasio E., Esposito R., Gambelunghe G., Misischi I., Raggiunti B., Rago T., Patelli G.L., D’Este S., Vitti P., Papini E. Outcomes and Risk Factors for Complications of Laser Ablation for Thyroid Nodules: A Multicenter Study on 1531 Patients, The Journal of Clinical Endocrinology & Metabolism, 2015, Volume 100, Issue 10, № 1, рр. 3903–3910.
11. Totoeva Z.N. Analysis of complications after various thyroid surgeries. EndoscopicSurgery, 2014, № 20(6), рр. 33–37. (In Russ.) https://doi.org/10.17116/endoskop2014633-37
Review
For citations:
Prazdnikov E.N., Rahimov F.E., Trandofilov M.M., Reznichenko V.V., Ovcharov S.E., Vakhromkin V.S. First experience of laser ablation for the treatment of nodular/multinodular non-toxic goiter at the russian university of medicine. Moscow Surgical Journal. 2025;(1):127-132. (In Russ.) https://doi.org/10.17238/2072-3180-2025-1-127-132
Views:
105
Email this article 