Repeated reconstructive operations for infection of synthetic prostheses in the aorto-ilio-femoral position
https://doi.org/10.17238/2072-3180-2022-2-58-66
Abstract
Introduction. The Aim. Improving the results of surgical treatment of patients with infection of the aortobedreno-bifurcation prosthesis.
Materials and methods. In the V.V. Veresaev City Clinical Hospital from 2002 to 2022, 70 patients were re-operated on the aorto-iliac-femoral zone due to infection of aorto-femoral bifurcation prostheses (68 patients) and endografts (2 patients). 15 (21.4%) patients underwent primary surgery for aneurysms of the infrarenal aorta, the rest due to occlusive stenotic lesions of the abdominal aorta and iliac arteries. In 37 (84%) patients, primary operations were performed for occlusive-stenotic lesions of the aorto-iliac zone. 38 (69%) of 55 patients with occlusive-stenotic lesions of the abdominal aorta and limb arteries were operated due to chronic ischemia of the 3rd and 4th degree.
Results. In the immediate postoperative period, 7 (10%) patients died. The main cause of death was sepsis with multiple organ failure – 6. In one observation, a patient with sepsis on the 4th day after surgery developed a clinical picture of peritonitis, which was caused by acute ulcers of the jejunum with perforation. Thrombosis of one of the branches of the prosthesis developed in 3 (4.2%) cases. In all observations, blood circulation in the extremities was restored.
Conclusion. The method of choice for infection of synthetic prostheses and endoprostheses in the aorto-iliac-femoral position is the use of the principles of active surgical treatment, with complete removal of the infected synthetic prosthesis with simultaneous in-situ replacement with autovenous shunts from the superficial femoral veins, active pre- and postoperative antibiotic therapy.
About the Authors
F. F. KhamitovRussian Federation
Khamitov Felix Flyurovich – MD, Professor, head of the department of vascular surgery
127644, Moscow, st. Lobnenskaya, 10
E. A. Matochkin
Russian Federation
Matochkin Evgenii Aleksandrovich – MD, PhD, cardiovascular surgeon of the Department of Vascular Surgery
127644, Moscow, st. Lobnenskaya, 10
K. V. Cheldiev
Russian Federation
Cheldiev Kazbek Valerievich – PhD, surgeon
127644, Moscow, st. Lobnenskaya, 10
V. S. Fomin
Russian Federation
Fomin Vladimir Sergeevich – MD, PhD, Associate Professor, surgeon
127644, Moscow, st. Lobnenskaya, 10
A. A. Bobylev
Russian Federation
Bobylev Aleksey Aleksandrovich – doctor, PhD, Deputy Chief Physician for Surgical Care
127644, Moscow, st. Lobnenskaya, 10
S. Yu. Belyshev
Russian Federation
Belyshev Sergey Yuryevich – doctor, Candidate of Medical Sciences, Deputy Chief Physician for Anesthesiology and Resuscitation
127644, Moscow, st. Lobnenskaya, 10
References
1. Clinical angiology. A guide for doctors. Edited by Academician of the Russian Academy of Medical Sciences Pokrovsky A.V. M. : Medicine, 2009. Vol. 1, 2. 808 p. (In Russ.)
2. Belov Yu.V., Stepanenko A.B. Repeated reconstructive operations on the aorta and main arteries. M. : MIA, 2009, 175 p. (In Russ.)
3. Shcherbyuk A.N., Inderbiev T.S., Ulyanov D.A., Vasiliev S. V. Repeated reconstructive operations on the aorta and arteries of the lower extremities. Surgery, 2002, № 9, рр. 64–69. (In Russ.)
4. Lemenev V. L., Mikhailov I.P. Surgical tactics in infection of vascular prosthesis. Surgery, 1997, № 3, рр. 10–12. (In Russ.)
5. Hart J.P., Eginton M.T., Brown K.R., Seabrook G.R., Lewis B.D., Edmiston C.E., Jr., et al. Operative strategies in aortic graft infections: is complete graft excision always necessary? Ann Vasc Surg., 2005, Mar; № 19(2), рр. 154–160.
6. Biro G., Szeberin Z., Nemes A., Acsady G. Cryopreserved homo-graft and autologous deep vein replacement for infrarenal aorto and iliaco-femoral graft infection: early and late results. J Cardovasc Surg (Torino), 2011, № 52(2), рр. 169–176.
7. Pupka A., Skora J., Janczak D., et al. In situ revascularization with silver coated polyester prosthesis and arterial homografts in patients with aortic graft infection – a prospective, comparative, single-centre study. Europen Journal of Vascular et Endovascular Surgery, 2011, Jan; № 41(1), рp. 61–67.
8. Seeger, J.M., Pretus, H.A., Welborn, M.B., Ozaki, C.K., Flynn, T.C., and Huber, T.S. Long-term outcome after treatment of aortic graft infection with staged extra-anatomic bypass grafting and aortic graft removal. (discussion 459-60). J Vasc Surg., 2000, № 32, рр. 451–459.
9. McKinsey J.F. Extra-Anatomic Reconstruction. Surgical Clinics of North America, 1995, № 75, (4,5), рр. 731–740.
10. Oderich, G.S., Panneton, J.M., Bower, T.C., Cherry, K.J. Jr, Rowland, C.M., Noel, A.A. et al. Infected aortic aneurysms: aggressive presentation, complicated early outcome, but durable results. J Vasc Surg., 2001, № 34, рр. 900–908.
11. Frankini A.D.; Lichtenfels E.; Frankini A.; Frankini T. Extra-anatomical arterial bypass of the aortoiliac segment: 15-year experience. J. vasc. bras., 2007, vol. 6, № 3, рр. 240–210.
12. Тorsello G., Sandmann W. In situ replacement of infected vascular prostheses with rifampin-soaked vascular grafts: Early results. J VAsc Surg., 1993, № 17, рр. 768–73.
13. Gabriel M., Pukacki F., Dzieciuchowicz L., Oszkinis G., Checinski P. Cryopreserved arterial allografts in the treatment of prosthetic graft infections. European Journal of Vascular and Endovascular Surgery, 2004, № 27(6), рр. 590–596.
14. Benjamin M.E., Cohn E.J. Jr, Purtill W.A., Hanna D.J., Lilly M.P., Flinn W.R. Arterial reconstruction with deep leg veins for the treatment of mycotic aneurysms. J Vasc Surg., 1999, Dec; № 30(6), рр. 1004–1015.
15. Argyriou C., Georgiadis G.S., Lazarides M.K., Georgakarakos E., Antoniou G.A. Endograft infection after endovascular abdominal aortic aneurysm repair: a systematic review and meta-analysis. J Endovasc Ther., 2017, № 24, рр. 688–697.
16. Smeds M.R., Duncan A.A., Harlander-Locke M.P., Lawrence P.F., Lyden S., Fatima J. et al. Treatment and outcomes of aortic endograft infection. J Vasc Surg., 2016, № 63, рр. 332–340.
17. Vogel T.R., Symons R., Flum D.R. The incidence and factors associated with graft infection after aortic aneurysm repair. J Vasc Surg., 2008, № 47, рр. 264–269.
18. Kakkos S.K., Bicknell C.D., Tsolakis I.A., Bergqvist D. Hellenic Cooperative Group on Aortic Surgery. Editor’s Choice – Management of secondary aorto-enteric and other abdominal arterio-enteric fistulas: a review and pooled data analysis. Eur J Vasc Endovasc Surg., 2016, № 52, рр. 770–786.
Review
For citations:
Khamitov F.F., Matochkin E.A., Cheldiev K.V., Fomin V.S., Bobylev A.A., Belyshev S.Yu. Repeated reconstructive operations for infection of synthetic prostheses in the aorto-ilio-femoral position. Moscow Surgical Journal. 2022;(2):58-66. (In Russ.) https://doi.org/10.17238/2072-3180-2022-2-58-66