Evaluation of the efficacy and safety of endoscopic botulinum toxin injections into the stomach in obese patients
https://doi.org/10.17238/2072-3180-2025-44-50
Abstract
Introduction. Aim. To evaluate the effectiveness and safety of endoscopic botulinum toxin therapy in bariatric patients.
Methods. A prospective controlled study of 48 patients with varying degrees of obesity who underwent endoscopic injection of botulinum toxin into the stomach floor was conducted. A dynamic assessment of subjective status and objective data, including body weight, daily calorie intake and laboratory data, was performed.
Results. The greatest decrease in body weight was observed in overweight patients, whose body weight loss averaged 14% relative to baseline values. The decrease in body weight in patients with grade I and II obesity was 5% and 6.4%, respectively. The average daily calorie intake decreases significantly in the first week after the procedure and is significantly lower throughout the follow-up period relative to the baseline data. The clinical and laboratory evaluation revealed no significant complications or toxic effects of the procedure.
Conclusion. The gastric botox therapy is a safe and effective method of body weight correction for overweight patients in preoperative preparation for bariatric surgery.
About the Authors
D. A. Kim
FSBEI HE "Novosibirsk State Medical University" of the Ministry of Health of Russian Federation; Medical Center AVICENNA
Russian Federation
Russian Federation
Kim Denis Alexandrovich – Ph.D., assistant of the Department of Postgraduate of Surgeons
Kommunisticheskaya st., 17/1, 630099, Novosibirsk
V. V. Anishchenko
FSBEI HE "Novosibirsk State Medical University" of the Ministry of Health of Russian Federation; Medical Center AVICENNA
Russian Federation
Russian Federation
Anisсhenko Vladimir Vladimirovich – Doctor of Medical Sciences, Professor, Head of the Department of Postgraduate of Surgeons
Kommunisticheskaya st., 17/1, 630099, Novosibirsk
A. O. Jin
FSBEI HE "Novosibirsk State Medical University" of the Ministry of Health of Russian Federation; Medical Center AVICENNA
Russian Federation
Russian Federation
Tszin Artem Olegovich – Postgraduate student of the Department of Postgraduate of Surgeons
Kommunisticheskaya st., 17/1, 630099, Novosibirsk
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Review
For citations:
Kim D.A., Anishchenko V.V., Jin A.O. Evaluation of the efficacy and safety of endoscopic botulinum toxin injections into the stomach in obese patients. Moscow Surgical Journal. 2025:44-50. (In Russ.) https://doi.org/10.17238/2072-3180-2025-44-50
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