Primary bariatric surgery – how to make a choice?
https://doi.org/10.17238/2072-3180-2025-20-30
Abstract
Introduction. Given the limited efficacy of conservative treatment methods, bariatric surgery is now considered the most effective approach for achieving sustained weight loss and metabolic improvement in patients with morbid obesity. Currently, there is no clearly defined algorithm for selecting primary bariatric procedures, which significantly complicates decision-making for early-career bariatric surgeons and multidisciplinary teams. Most specialists rely on expert opinions from leading bariatric surgeons and clinical obesity treatment guidelines.
Materials and Methods. We analyzed contemporary approaches to optimal bariatric procedure selection based on clinical guidelines from major international and Russian organizations and current research data.
Results. Based on the comparative benefits, limitations, and patient-specific factors, we developed an algorithm for selecting primary bariatric procedures for patients with obesity and metabolic syndrome.
Conclusion. The proposed algorithm demonstrates that selection of primary bariatric surgery should be based on multiple factors affecting procedural safety and efficacy. Implementation of this algorithm helps standardize surgical decision-making while allowing personalized adaptation of surgical strategy according to individual patient characteristics, thereby reducing complication risks and improving outcomes.
About the Authors
A. E. NeymarkRussian Federation
Neymark Alexander Evgenievich – Candidate of Medical Sciences, Associate Professor, Leading Researcher of the Research Institute of Diabetology of the Institute of Endocrinology, Surgeon
197341, Akkuratova str., 2, Saint Petersburg
S. E. Lapshina
Russian Federation
Lapshina Sofya Evgenyevna – Surgeon, Assistant at the Department of Faculty Surgery with the Clinic of the Institute of Medical Education
197341, Akkuratova str., 2, Saint Petersburg
B. V. Sigua
Russian Federation
Sigua Badri Valerievich – MD, Professor, Head of the Department of General Surgery, Faculty of Medicine, Institute of Medical Education
197341, Akkuratova str., 2, Saint Petersburg
References
1. World Health Organization. Obesity and overweight, 2022. https://www.who.int/news-room/fact-sheets/detail/obesity-and-overweight (accessed 07/16/2025). [In Russ.]
2. American Society for Metabolic and Bariatric Surgery (ASMBS). Clinical Practice Guidelines. https://asmbs.org/resources/practice-parame-ters-guidelines (accessed 07/16/2025). [In Russ.]
3. Schauer PR, Bhatt DL, Kirwan JP, et al. Bariatric Surgery versus Intensive Medical Therapy for Diabetes – 5-Year Outcomes. JAMA. 2022. https://jamanetwork.com/journals/jama/fullarticle/2785835
4. 8th IFSO 2023 Registry Report. https://www.ifso.com/pdf/8th-if-so-registry-report-2024-latest-new.pdf (accessed 07/16/2025)/ [In Russ.]
5. Khatsiev B.B., Yashkov Yu.I., Bordan N.S. [et al.]. III Otchet rossiyskogo natsional’nogo bariatricheskogo reestra: informatsionno-analiticheskiy sbornik za 2024 god [III Report of the Russian National Bariatric Registry: Information and analytical collection for 2024]. Stavropol, Agrus Stavropol State Agrarian Univ. Publ., 2025, 52 p. (In Russ.)
6. Dedov I.I., Mel’nichenko G.A., Shestakova M.V., Troshina E.A., Mazurina N.V., Shestakova E.A., Yashkov Yu.I., Neimark A.E., Biryukova E.V., Bondarenko I.Z., Bordan N.S., Dzgoeva F.H., Ershova E.V., Komshilova K.A., Mkrtumyan A.M., Petunina N.A., Romantsova T.I., Starostina E.G., Strongin L.G., Suplotova L.A., Fadeyev V.V. Russian national clinical recommendations for morbid obesity treatment in adults. 3rd revision (Morbid obesity treatment in adults). Obesity and metabolism, 2018, № 15(1), pp. 53–70. (In Russ.) https://doi.org/10.14341/omet2018153-70
7. Akhter Z., Rankin J., Ceulemans D., Ngongalah L., Ackroyd R., Devlieger R., Vieira R., Heslehurst N. Pregnancy after bariatric surgery and adverse perinatal outcomes: A systematic review and meta-analysis. PLoS Med., 2019, 16 (8), рр. e1002866. https://doi.org/10.1371/journal.pmed.1002866
8. Neimark A.Е., Molotkova M.A., Galchenko M.I., Lapshina S.E., Makarova E.O., Afonin S.V., Sholokhov G.V., Maсievskaya A.Y. DRAMS — the new system for predicting type 2 diabetes mellitus remission after baritaric surgery. Diabetes mellitus, 2024, № 27(5), pp. 451–460. (In Russ.) https://doi.org/10.14341/DM13169. – EDN ABDBKC
9. Mehdorn A.S., Moulla Y., Mehdorn M., Dietrich A., Schönfels W., Becker T., Braun F., Beckmann J.H., Linecker M. Bariatric surgery in liver cirrhosis. Front. Surg., 2022, № 9, рр. 986297. https://doi.org/10.3389/fsurg.2022.986297
10. Berko O.M., Kornyushin O.V., Mekhtiev S.N., Neimark A.E. Optimization of the choice of bariatric surgery in a patient with heartburn and gastroesophageal reflux disease. Moscow Surgical Journal, 2022, № 3, pp. 106–115. (In Russ.) https://doi.org/10.17238/2072-3180-2022-3-106-115
11. Mingrone G., Panunzi S., De Gaetano A. et al. Metabolic surgery versus conventional medical therapy in patients with type 2 diabetes: 10-year follow-up of an open-label, single-centre, randomised controlled trial. Lancet, 2021, № 397 (10271), pp. 293–304. https://doi.org/10.1016/S0140-6736(20)32649-0
12. Salame M., Jawhar N., Belluzzi A., Al-Kordi M., Storm A.C., Abu Dayyeh B.K., Ghanem O.M. Marginal Ulcers after Roux-en-Y Gastric By-pass: Etiology, Diagnosis, and Management. J. Clin. Med., 2023, № 12 (13), рр. 4336. https://doi.org/10.3390/jcm12134336
13. Miedziaszczyk M., Ciabach P., Szałek E. The Effects of Bariatric Surgery and Gastrectomy on the Absorption of Drugs, Vitamins, and Mineral Elements. Pharmaceutics, 2021, № 13 (12), рр. 2111. https://doi.org/10.3390/pharmaceutics13122111
14. Zino L., Kingma J.S., Marzolini C., Richel O., Burger D.M., Colbers A. Implications of Bariatric Surgery on the Pharmacokinetics of Antiretrovirals in People Living with HIV. Clin. Pharmacokinet., 2022, № 61 (5), pp. 619–635. https://doi.org/10.1007/s40262-022-01120-7
15. Kermansaravi M., Shahsavan M., Amr B., Stier C., Parmar C., Chiappetta S. Dumping Syndrome After One Anastomosis Gastric Bypass-A Systematic Review. Obes. Surg., 2025, № 35 (6), pp. 2310–2320. https://doi.org/10.1007/s11695-025-07860-2.
16. Bettini S., Segato G., Prevedello L., Fabris R., Prà C.D., Zabeo E., Compagnin C., De Luca F., Finco C., Foletto M. et al. Improvement of Lipid Profile after One-Anastomosis Gastric Bypass Compared to Sleeve Gastrectomy. Nutrients, 2021, № 13 (8), 2770. https://doi.org/10.3390/nu13082770
17. Sanni A., Perez S., Medbery R., Urrego H.D., McCready C., Toro J.P., Patel A.D., Lin E., Sweeney J.F., Davis S.S. Postoperative complications in bariatric surgery using age and BMI stratification: a study using ACS-NSQIP data. Surg. Endosc., 2014, № 28 (12), pp. 3302–3309. https://doi.org/10.1007/s00464-014-3606-7
18. Howell R.S., Liu H.H., Boinpally H., Akerman M., Carruthers E., Brathwaite B.M., Petrone P., Brathwaite C.E.M. Outcomes of Bariatric Surgery: Patients with Body Mass Index 60 or Greater. JSLS, 2021, № 25 (2), рр. e2020.00089. https://doi.org/10.4293/JSLS.2020.00089
19. Wunker C., Kumar S., Hallowell P. et al. Bariatric surgery and relevant comorbidities: a systematic review and meta-analysis. Surg. Endosc., 2025, № 39 (4), pp. 1419–1448. https://doi.org/10.1007/s00464-025-11528-4
20. Belluzzi A., Sample J.W., Marrero K., Tomey D., Puvvadi S., Sharma I., Ghanem O.M. Rare Complications Following Laparoscopic Sleeve Gastrectomy. J. Clin. Med., 2024, № 13 (15), рр. 4456. https://doi.org/10.3390/jcm13154456
21. Hadi Y.B., Mann R., Sohail A.H., Shah-Khan S.M., Szoka N., Abunnaja S., Tabone L.E., Thakkar S., Singh S. Metabolic bone disease and fracture risk after gastric bypass and sleeve gastrectomy: comparative analysis of a multi-institutional research network. Surg. Obes. Relat. Dis., 2022, № 18 (5), pp. 604–609. https://doi.org/10.1016/j.soard.2021.12.020
22. Ritz P., Topart P., Benchetrit S., Tuyeras G., Lepage B., Mouiel J., Becouarn G., Pattou F., Chevallier J.M. Benefits and risks of bariatric surgery in patients aged more than 60 years. Surg. Obes. Relat. Dis., 2014, № 10 (3), pp. 389–396. https://doi.org/10.1016/j.soard.2013.12.012
23. Seeras K, Acho RJ, Lopez PP. Roux-en-Y Gastric Bypass Chronic Complications. StatPearls Publishing, 2025.
24. Nunes R., Santos-Sousa H., Vieira S., Nogueiro J., Bouça-Machado R., Pereira A., Carneiro S., Costa-Pinho A., Lima-da-Costa E., Preto J. Vitamin B Complex Deficiency After Roux-en-Y Gastric Bypass and Sleeve Gastrectomy-a Systematic Review and Meta-Analysis. Obes. Surg., 2022, № 32 (3), pp. 873–891. http://doi.org/10.1007/s11695-021-05783-2
25. Burjonrappa S, Grover K. Bariatric Surgery Complications. Stat-Pearls Publishing, 2025.
26. Brockmeyer J.R., Coffin E.M. Gastric bypass: evolution toward mini-invasive techniques and long-term results. Mini-invasive Surg., 2025, № 9, рр. 17. http://doi.org/10.20517/2574-1225.2024.86
27. Kingma J.S., Burgers D.M.T., Monpellier V.M., Wiezer M.J., Blussé van Oud-Alblas H.J., Vaughns J.D., Sherwin C.M.T., Knibbe C.A.J. Oral drug dosing following bariatric surgery: General concepts and specific dosing advice. Br. J. Clin. Pharmacol., 2021, № 87 (12), pp. 4560–4576. https://doi.org/10.1111/bcp.14913
28. Bischoff S.C., Barazzoni R., Busetto L., Campmans-Kuijpers M., Cardinale V., Chermesh I., Eshraghian A., Kani H.T., Khannoussi W., Lacaze L., Léon-Sanz M., Mendive J.M., Müller M.W., Ockenga J., Tacke F., Thorell A., Vranesic Bender D., Weimann A., Cuerda C. European guideline on obesity care in patients with gastrointestinal and liver diseases. United European Gastroenterol. J., 2022, № 10 (7), pp. 663–720. https://doi.org/10.1002/ueg2.12280
29. Aref H. Single-Anastomosis Duodeno-ileal Bypass with Sleeve Gastrectomy as an Ultimate Option for Diabetics with Severe Obesity: A Scoping Review. Curr. Surg. Rep., 2024, № 12 (2), pp. 97–103. https://doi.org/10.1007/s40137-024-00392-1
30. Batista M.V., Ulrich J., Costa L., Ribeiro L.A. Multiple Primary Malignancies in Head and Neck Cancer: A University Hospital Experience Over a Five-Year Period. Cureus, 2021, № 13 (8), рр. e17349. https://doi.org/10.7759/cureus.17349
Review
For citations:
Neymark A.E., Lapshina S.E., Sigua B.V. Primary bariatric surgery – how to make a choice? Moscow Surgical Journal. 2025:20-30. (In Russ.) https://doi.org/10.17238/2072-3180-2025-20-30