Presents a clinical case describing the possibility of combined treatment the patient 67 years old with severe premorbidal background, which was successfully performed transanal resection of the rectum after effective preoperative chemoradiotherapy. The conclusion about the effectiveness of the combined treatment of patients with rectal cancer in older age groups.

Laparoscopic interventions after earlier performed open abdominal operations are becoming more common these days. However, a laparoscopic cholecystectomy after an inferior vena cava plication performed from a wide oblique approach in the right hypochondrium is not frequently found. Since the ap- proach to inferior vena cava is carried out by the mobilisation of the duodenum, it causes a massive adhesive process in the area of hepatoduodenal ligament and in the right subhepatic space.This article describes a clinical case of a successful application of laparoscopy capabilities in a patient, who had undergone an inferior vena cava plication for its thrombosis associated with hormonal medication.

Tibiofibular syndesmosis is one of the most important stability issues of the talocrural joint. Most commonly tibiofibular syndesmosis becomes damaged in cases of pronation-external rotational mechanism of the malleolar fracture. The issues on the necessity of stabilizing the tibiofibular syndesmosis were repeatedly studied during multiple cadaver and clinical trials, however, no uniform recommendations were formulated at the present moment. The aim of the present review is to formulate the indications for the procedure of tibiofibular syndesmosis stabilization.

Intussusception of the intestine - a mixture of intestinal obstruction due to isoperistaltic introduction of the proximal section of the intestine distally (rarely Vice versa).Intestinal obstruction of tumor Genesis is a syndrome characterized by disturbance of promotion of the content through the digestive tract and are caused by mechanical obstacle, which is a malignant or benign neoplasm of the intestinesThe relevance of this article is to educate young surgeons on the causes, clinical picture, complications, methods of diagnosis and treatment of intussusception.

The article is devoted to the topical medico-social and medico-economic problem of modern gynecology is the problem of endometriosis.The aim of the study was to determine the characteristics of miRnA expression in patients with external genital endometriosis.Material and methods: Investigated 33 sample of blood plasma of patients with III-IV stages and of 33 samples of blood plasma of patients with I-II stages of external genital endometriosis and 10 plasma samples of healthy women as a negative control. The analysis of the relative expression of circulating miRnAs in plasma by the method of spectrophotometry on the nanoDrop 1000 machine (nanoDrop Technologies Inc., USA).The results of the study. The research showed a significant increase in the relative expression levels of microRnA-30C and microRnA-133a with external genital endometriosis in contrast to that in the comparison group (p < 0.05).Conclusion: Вased on the quantitative assessment of the content circulating microRnA, we can recommend microRnA-30C, microRnA-155, microRnA-574*, microRnA-425, microRnA-133a for inclusion in the diagnostic panel of endometriosis.

The article is a literature review of the use of transjugular intrahepatic portosystemic shunting (TIPS) in patients with cirrhosis of the liver. A historical reference is given on the formation of the method and the theoretical justification for its application. The indications and contraindications to the TIPS are considered, the most common complications after the TIPS are mentioned.