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The first experience of hybrid surgical treatment in a patient with a perforative duodenal ulcer using a fully covered self-expandable nitinol stent (clinical case)

https://doi.org/10.17238/2072-3180-2025-4-138-144

Abstract

Introduction. Perforation of gastric and duodenal ulcers continues to be one of the most widespread complications of peptic ulcer disease. The main treatment method is surgical. The most common type of surgical intervention is videolaparoscopic suturing of a defect. However, in conditions of diffuse peritonitis, large infiltrative inflammation, and comorbidity of patients, especially in the presence of diabetes mellitus, the risk of suture failure is high. In order to minimize postoperative complications, new surgical techniques are being sought to avoid repeated surgical interventions.
The purpose of the study. Improving the results of treatment of patients with perforated gastroduodenal ulcers by evaluating the effectiveness of a hybrid surgical intervention.
Materials and methods of research. The article presents a clinical case of a 54-year-old patient with a diagnosis of duodenal ulcer perforation. Diffuse serous fibrinous peritonitis. The patient has numerous chronic non-communicable diseases. The Charlson Comorbidity Index (CCI) is 6.
Treatment results. The patient underwent a hybrid surgical intervention – videolaparoscopic suturing of the perforation, preventive endoscopic stenting of the perforation zone. No complications were in the postoperative period. The length of hospital stay was 9 days.
Conclusions. Hybrid minimally invasive intervention made it possible to avoid the transition to laparotomy and reduce the risk of intra- and postoperative complications in a comorbid patient. However, further studies are required for meaningful evaluations of the effectiveness of this surgical method.

About the Authors

P. A. Yartsev
N.V. Sklifosovsky Research Institute For Emergency Medicine
Russian Federation

Yartsev Petr Andreevich – PhD, Professor, Head of the Scientific Department of Emergency Surgery, Endoscopy and Intensive Care.

129090, Bolʹshaya Sukharevskaya Ploshchadʹ, 3, Moscow



Y. K. Sajaya
N.V. Sklifosovsky Research Institute For Emergency Medicine
Russian Federation

Sadzhaya Yiri Konstantinovitch – surgeon, Department of Emergency Surgery, Endoscopy and Intensive Care 

129090, Bolʹshaya Sukharevskaya Ploshchadʹ, 3, Moscow



M. M. Rogal
N.V. Sklifosovsky Research Institute For Emergency Medicine
Russian Federation

Rogal Mikhail Mikhailovich – PhD, surgeon, research associate, Department of Emergency Surgery, Endoscopy and Intensive Care 

129090, Bolʹshaya Sukharevskaya Ploshchadʹ, 3, Moscow



N. A. Stinskaya
N.V. Sklifosovsky Research Institute For Emergency Medicine
Russian Federation

Stinskaya Nadezhda Aleksandrovna – researcher 

129090, Bolʹshaya Sukharevskaya Ploshchadʹ, 3, Moscow



I. I. Kirsanov
N.V. Sklifosovsky Research Institute For Emergency Medicine
Russian Federation

Kirsanov Ilya Igorevich – PhD, Head of the emergency surgery unit, surgeon 

129090, Bolʹshaya Sukharevskaya Ploshchadʹ, 3, Moscow



Sh. A. Baskhanov
N.V. Sklifosovsky Research Institute For Emergency Medicine
Russian Federation

Baskhanov Shamil Askhabovich – endoscopist, Department of Emergency Surgery, Endoscopy and Intensive Care 

129090, Bolʹshaya Sukharevskaya Ploshchadʹ, 3, Moscow



V. V. Kazakova
N.V. Sklifosovsky Research Institute For Emergency Medicine
Russian Federation

Kazakova Victoria Viktorovna – PhD, surgeon, coloproctologist, researcher, Department of Emergency Surgery, Endoscopy and Intensive Care 

129090, Bolʹshaya Sukharevskaya Ploshchadʹ, 3, Moscow



References

1. Revishvili A.Sh., Olovyanny V.E., Kuznetsov A.V. Emergency laparoscopic surgery in Russia: a current state. Pirogov Russian Journal of Surgery, 2024, № 9, pp. 5–15. (In Russ.). https://doi.org/10.17116/hirurgia20240915

2. Tarasconi A., Coccolini F., Biffl W.L., Tomasoni M., Ansaloni L., Picetti E., Molfino S., Shelat V., Cimbanassi S., Weber D.G., Abu-Zidan F.M., Campanile F.C., Di Saverio S., Baiocchi G.L., Casella C., Kelly M.D., Kirkpatrick A.W., Leppaniemi A., Moore E.E., Peitzman A., Fraga G.P., Ceresoli M., Maier R.V., Wani I., Pattonieri V., Perrone G., Velmahos G., Sugrue M., Sartelli M., Kluger Y., Catena F. Perforated and bleeding peptic ulcer: WSES guidelines. World J. Emerg. Surg., 2020, № 15, рр. 3. Published 2020 Jan 7. https://doi.org/10.1186/s13017-019-0283-9

3. Rasslan S., Coimbra R., Rasslan R., Utiyama E.M. Management of perforated peptic ulcer: What you need to know. J. Trauma Acute Care Surg., 2025, № 99(1), pp. 1–9. https://doi.org/10.1097/TA.0000000000004561

4. Panin S. I., Suvorov V. A., Bykov A.V., Kovalenko N. V., Postolov M. P., Bublikov A. E., Mikhin E. S., Linchenko A. A. The prognostic role of comorbid status in assessing the results of surgical treatment of patients with perforated ulcers. Bulletin of Surgery named after I. I. Grekov, 2022, № 181(3), pp. 20–27. (In Russ.) https://doi.org/10.24884/40042-4625-2022-181-3-20-27.

5. Kirsanov I.I., Yartsev P.A., Kazakova V.V. Perforated gastroduodenal ulcers. In: Handbook of Emergency Medicine. The experience of the N.V. Sklifosovsky Research Institute of Emergency Medicine: in 3 volumes / edited by S.S. Petrikov. M. : ICAR, 2023. Vol. 2, Section 10: Surgery, Ch. 9. pp.782–806. (In Russ.)

6. Shreya A., Sahla S., Gurushankari B., Shivakumar M., Rifai, Kate V., Sureshkumar S., Mahalakshmy T. Spectrum of perforated peptic ulcer disease in a tertiary care hospital in South India: predictors of morbidity and mortality. ANZ J Surg., 2024, № 94(3), pp. 366–370. https://doi.org/10.1111/ans.18831

7. Arshad S.A., Murphy P., Gould J.C. Management of Perforated Peptic Ulcer: A Review. JAMA Surg., 2025, № 160(4), pp. 450–454. https://doi.org/10.1001/jamasurg.2024.6724

8. Pelloni M., Afonso-Luís N., Marchena-Gomez J., Piñero-González L., Ortíz-López D., Acosta-Mérida M.A., Rahy-Martín A. Comparative study of postoperative complications after open and laparoscopic surgery of the perforated peptic ulcer: Advantages of the laparoscopic approach. Asian. J. Surg., 2022, № 45(4), pp. 1007–1013. https://doi.org/10.1016/j.asjsur.2021.08.059

9. Sokhal B.S., Mohamedahmed A., Zaman S., Wuheb A.A., Abdalla H.E., Husain N., Hajibandeh S., Hajibandeh S. Laparoscopic versus open repair for peptic ulcer perforation: a systematic review, meta-analysis and trial sequential analysis of randomised controlled trials. Time to conclude! Ann. R. Coll. Surg. Engl, 2025, № 107(5), pp. 331–345. https://doi.org/10.1308/rcsann.2024.0082

10. Abouelazayem M., Jain R., Wilson M.S.J., Martinino A., Balasubaramaniam V., Biffl W., Coccolini F., Riera M., Wadhawan H., Wazir I., Abderaouf B., Abramov D., Abu Jayyab M.A., Al-Shami K., Alfarwan A., Alhajami F.M., Alkaseek A., Alozairi O., Ammar A.S., Atar B., Baatarjav G.E., Bains L., Bakri A., Bayramov N., Bhojwani R., Brachini G., Calini G., Campanelli M., Cheng S.Y., Choudhary C.S., Chowdhury S., Colak E., Das J.K., Dawani S., Dönmez T., Elzayat I., Erdene S., Faizi T.Q., Frountzas M., Gafsi B., Gentileschi P., Guler M., Gupta G., Harkati N.E., Harris M., Hasan D.M., Irowa O.O., Jafferi S., Jain S.A., Jun Han L., Kandiboyina S.M., Karabulut M., Khamees A., Khan S., Khan M.M., Khaw C.J., Kisielewski M., Klib M., Košir J.A., Krawczyk W.J., Lisi G., Makama J.G., Maqbool B., Marques C.N., Meric S., Mietła M.P., Ads A.M., Muhumuza J., Mulita F., Mustafayeva M., Omar M.A., Omarov T., Pathak A.A., Paul R., Pavone G., Podda M., Raja Ram N.K., Rauf F., Rauf S., Safy A.M., Sandag E., Şanlı A.N., Siddiqui A.Z., Sotiropoulou M., Talib V., Tatar C., Thota A., Tokocin M., Tolat A., Uchikov P.A., Valenzuela J.I., Venkatappa S.K., Verras G.I., Vlahović I., Zreeg D.A.S., Cardoso V.R., Gkoutos G.V., Singhal R., Mahawar K.; GRACE Study Collaborative Group. Global 30-day morbidity and mortality of surgery for perforated peptic ulcer: GRACE study. Surg. Endosc., 2024, № 38(8), pp. 4402–4414. https://doi.org/10.1007/s00464-024-10881-0

11. Lund S., Chauhan K.K., Zietlow J., Stephens D., Zietlow S., Strajina V., Turay D., Zielinski M. Risk Factors for Gastrointestinal Leak after Perforated Peptic Ulcer Disease Operative Repair. Am. Surg., 2021, № 87(12), pp. 1879–1885. https://doi.org/10.1177/00031348211056263

12. Stavrou G., Rafailidis V., Diamantidou A., Kouskouras C., Michalopoulos A., Kotzampassi K. Successful closure of a complicated duodenal ulcer perforation with an expandable esophageal stent. Asian. J. Endosc. Surg., 2019, № 12(3), рр. 326–328. https://doi.org/10.1111/ases.12642

13. Bergstrom M., Arroyo Vazquez J.A., Park P.O. Self-expandable metal stents as a new treatment option for perforated duodenal ulcer. Endoscopy, 2013, № 45(3), pp. 222–225. https://doi.org/10.1055/s-0032-1325885

14. Holm T.E., Olafsson S., Kazaryan A.M. Endoscopic stent treatment of a duodenal ulcer perforation using a semi-covered stent. Clin. Case Rep., 2019, № 7(8), pp. 1554–1556. https://doi.org/10.1002/ccr3.2293 eCollection 2019 Aug.

15. Ngamruengphong S., Sharaiha R.Z., Sethi A., Siddiqui A.A., DiMaio C.J., Gonzalez S., Im J., Rogart J.N., Jagroop S., Widmer J., Hasan R.A., Laique S., Gonda T., Poneros J., Desai A., Tyberg A., Kumbhari V., El Zein M., Abdelgelil A., Besharati S., Hernaez R., Okolo P.I., Singh V., Kalloo A.N., Kahaleh M., Khashab M.A. Endoscopic suturing for the prevention of stent migration in benign upper gastrointestinal conditions: a comparative multicenter. Endoscopy, 2016, № 48(9), pp. 808–808. https://doi.org/10.1055/s-0042-108567


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For citations:


Yartsev P.A., Sajaya Y.K., Rogal M.M., Stinskaya N.A., Kirsanov I.I., Baskhanov Sh.A., Kazakova V.V. The first experience of hybrid surgical treatment in a patient with a perforative duodenal ulcer using a fully covered self-expandable nitinol stent (clinical case). Moscow Surgical Journal. 2025;(4):138-144. (In Russ.) https://doi.org/10.17238/2072-3180-2025-4-138-144

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