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Phylloid tumors of the mammary glands. Features of instrumental diagnostics and morphological structure

https://doi.org/10.17238/2072-3180-2024-2-93-100

Abstract

Non-epithelial malignant breast tumors include both non-epithelial and fibroepithelial tumors, primarily phylloid tumors (0,3–1 %) and sarcomas (0,2–0,6 %) [1, 2]. Phylloid tumors are considered in this group due to the fact that they are rare, fibroepithelial tumors that they have a biphasic structure and a peculiar clinical course [3]. Due to the with a small number of randomized research studying this pathology, there is currently no standardized approach to diagnosis and little-studied tactics of their complex treatment [4].

Relevance. According to statistics from international studies, the frequency of malignant variants of phylloid tumors varies widely: from 2 % to 45 %. The malignant potential of the tumor is determined by the malignancy of the non-epithelial component, to which a relatively small part of the tumor is most often exposed, while the rest of it may have morphological signs of a benign process. This is the reason for the difficulty of verifying the tumor process at the diagnostic stage. Taking into account the various options of the clinical course and morphological features, phylloid tumors should be considered as a whole complex of tumors of fibroepithelial origin.

The purpose of the study. To analyze and systematize data on the features of instrumental diagnosis and morphological structure of phylloid tumors of the mammary glands.

Materials and methods of research. The search for literary sources was carried out in PubMed according to the following dictionary queries: "phylloid tumors", "leaf-shaped tumors", "breast sarcomas". The search time interval was 2005–2023.

About the Authors

M. Sh. Zugumova
State Research Center – Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency (SRC - FMBC); SRC-FMBC Medical Biological University for Innovation and Continuing Education
Russian Federation

Zugumova Mariam Shamilovna – Assistant

123182, 46 Zhivopisnaya str., Moscow



N. G. Stepanyants
State Research Center – Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency (SRC - FMBC); SRC-FMBC Medical Biological University for Innovation and Continuing Education
Russian Federation

Stepanyants Nikolay Georgievich – M.D.

123098, 23 Marshal Novikov str., Moscow



А. А. Zavyalov
State Research Center – Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency (SRC - FMBC); SRC-FMBC Medical Biological University for Innovation and Continuing Education
Russian Federation

 Zavyalov Alexander Alexandrovich – M.D., Professor

123098, 23 Marshal Novikov str., Moscow



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Review

For citations:


Zugumova M.Sh., Stepanyants N.G., Zavyalov А.А. Phylloid tumors of the mammary glands. Features of instrumental diagnostics and morphological structure. Moscow Surgical Journal. 2024;(2):93-100. (In Russ.) https://doi.org/10.17238/2072-3180-2024-2-93-100

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ISSN 2072-3180 (Print)