Malignant phylloid breast tumor
https://doi.org/10.17238/2072-3180-2023-2-116-122
Abstract
Introduction. A phylloid tumor, also known as a leaf–shaped or intracanalicular fibroadenoma with a cellular stroma is a rare pathology that accounts for 0.3–0.5 % of all breast neoplasms. A phylloid tumor is characterized by the potential for transformation into a breast sarcoma due to malignant changes in the stroma. Breast sarcoma is a rare non–epithelial malignant tumor that occurs in 1 % of cases of the total number of malignant breast tumors and 5% of all soft tissue sarcomas. Primary breast sarcomas are rare and histologically heterogeneous malignant neoplasms, publications on this topic are limited.
Description of the clinical case. The article presents a clinical observation of a patient with a malignant phylloid breast tumor who underwent surgical treatment in the volume of a radical mastectomy according to Madden.
Discussion. The clinical case is interesting for the rare type of fibroepithelial tumor and the difficulty of final verification of histogenesis at the preoperative stage due to the difficulty of differentiating malignant leaf-shaped tumor from metaplastic carcinoma.
Conclusions. Specialists will have to conduct a considerable number of histochemical and genetic studies of a large number of cases of malignant phylloid breast tumors to develop an effective algorithm for the treatment of this pathology.
About the Authors
M. Sh. Zugumova
SRC-FMBC Medical Biological University for Innovation and Continuing Education
Russian Federation
Russian Federation
Mariam Shamilovna Zugumova, Assistant
123182
46 Zhivopisnaya str.
Moscow
N. G. Stepanyants
SRC-FMBC Medical Biological University for Innovation and Continuing Education; State Research Center – Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency (SRC - FMBC)
Russian Federation
Russian Federation
Nikolay Georgievich Stepanyants, M. D.
123182
46 Zhivopisnaya str.
123098
23 Marshal Novikov str.
Moscow
A. A. Zavyalov
SRC-FMBC Medical Biological University for Innovation and Continuing Education; State Research Center – Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency (SRC - FMBC)
Russian Federation
Russian Federation
Alexander Alexandrovich Zavyalov, M. D., Professor
123182
46 Zhivopisnaya str.
123098
23 Marshal Novikov str.
Moscow
K. A. Pavlov
State Research Center – Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency (SRC - FMBC)
Russian Federation
Russian Federation
Konstantin Anatolievich Pavlov, M. D., PhD, Pathologist
123098
23 Marshal Novikov str.
Moscow
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Review
For citations:
Zugumova M.Sh., Stepanyants N.G., Zavyalov A.A., Pavlov K.A. Malignant phylloid breast tumor. Moscow Surgical Journal. 2023;(2):116-122. (In Russ.) https://doi.org/10.17238/2072-3180-2023-2-116-122
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