Evaluation of the effectiveness of nonoperative management of abdominal organ with spontaneously stopped internal bleeding in a model of combined radiation injury
https://doi.org/10.17238/2072-3180-2022-4-61-69
Abstract
Introduction. The results of the research conducted in the 80s of the twentieth century allowed us to formulate the basic principles of surgical treatment of combined radiation-mechanical lesions (CRMP), however, the possibilities of new therapeutic technologies developed in recent decades in relation to CRMP have not been sufficiently studied. The tactic of non-surgical treatment (NOL) of abdominal injuries with stopped internal bleeding is increasingly used for abdominal injuries, however, we have not found reports of the use of this tactic in CRMP in the available literature.
The aim of the study was to conduct a comparative experimental assessment of the effectiveness of the tactics of NOL and laparotomy in abdominal injuries with stopped intra-abdominal bleeding as a component of CRMP.
Materials and methods. The study was conducted on 41 rabbits of the Soviet Chinchilla breed, males weighing 2,5–3,0 kg. Rabbits were randomly divided into 5 groups depending on the experimental conditions.
The results of the study. The choice of the method of surgical treatment of abdominal injuries with stopped internal bleeding – NOL or laparotomy, modifies the nature of the course of PKK, but not its outcome. It was found that the NOL tactic does not cause the death of animals in the early period of modeling the mechanical component of the CRMP, since it is not accompanied by additional trauma and additional intraoperative blood loss.
Conclusion. The results obtained allow us to assert that the choice of tactics for NOL injuries of abdominal organs with stopped internal bleeding in CRMP in the experiment contributes to a more favorable flow of radiation and mechanical components compared with the results of the classical approach with surgical removal of abdominal injuries.
About the Authors
P. E. KraynyukovRussian Federation
Kraynyukov Pavel Evgenievich – Head of the hospital, Major General of the medical service, Doctor of Medical Sciences, Candidate of Military Sciences
8 Bolshaya Olenya str., Moscow, 107014
A. V. Zhabin
Russian Federation
Zhabin Anatoly Valerievich – doctoral student at the Department
of Military Field Surgery, major of the Medical Service, Candidate of
Medical Sciences
6 Akademika Lebedeva Street, Saint Petersburg, 194044
A. M. Nosov
Russian Federation
Nosov Artem Mikhailovich – Head of the Research Laboratory
(Military Surgery) of the Research Department (Experimental Medicine) of the Research Center, Major of the Medical Service, Candidate of Medical Sciences
6 Akademika Lebedeva Street, Saint Petersburg, 194044
A. B. Seleznev
Russian Federation
Seleznev Alexey Borisovich – Deputy Head of the Research Testing Center (Biomedical protection), Colonel of the medical service, Candidate of Medical Sciences, Associate Professor. Associate Professor of the Department of Toxicology, Extreme and Diving Medicine
195043, St. Petersburg, Lesoparkovaya str., 4;
191015, Saint Petersburg, Kirochnaya str., 4
I. M. Samokhvalov
Russian Federation
Samokhvalov Igor Markellovich – Head of the Department of
Military Field Surgery, retired Colonel of the Medical Service, Honored Doctor of the Russian Federation, Doctor of Medical Sciences, Professor
194044, Saint Petersburg, 6 Akademika Lebedeva Street
A. A. Pichugin
Russian Federation
Pichugin Artem Andreevich – Lecturer of the Department of
Military Field Surgery, Lieutenant Colonel of the Medical Service,
Candidate of Medical Sciences
194044, Saint Petersburg, 6 Akademika Lebedeva Street
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Review
For citations:
Kraynyukov P.E., Zhabin A.V., Nosov A.M., Seleznev A.B., Samokhvalov I.M., Pichugin A.A. Evaluation of the effectiveness of nonoperative management of abdominal organ with spontaneously stopped internal bleeding in a model of combined radiation injury. Moscow Surgical Journal. 2022;(4):61-69. (In Russ.) https://doi.org/10.17238/2072-3180-2022-4-61-69