The prognostic value of diarem and Ad-Diarem in patients with type 2 diabetes mellitus after bariatric surgery
https://doi.org/10.17238/2072-3180-2022-4-41-48
Abstract
Introduction. Bariatric surgery shows excellent results in the treatment of obesity and comorbidities including type 2 diabetes. To predict the effect of surgical treatment of type 2 diabetes mellitus, several scales have been proposed, including DiaRem and Ad-DiaRem.
Materials and methods of research. Based on a retrospective analysis study, 38 patients with type 2 diabetes were identified after bariatric surgery with a follow-up period of at least 1 year. The KNIME Analytics Platform 4.3.6 (KNIME AG, Switzerland) was used for data processing.
Treatment results. Among 38 patients, 12,8 % achieved partial remission of diabetes, 52,6 % complete remission, and 31,6 % did not achieve remission. According to the DiaRem, no significant results were detected in the remission groups (χ2 = 6,76, DF = 4, p-value = 0,15). AUC = 0,744, k = 0,383. DiaRem scale have a low predictive value. A significant result was obtained on the Ad-DiaRem (χ2 = 22,0, DF = 4, p-value = 0,0002). AUC = 0,88, k = 0,632. Ad-DiaRem predictive value is high.
Conclusion. The Ad-DiaRem have a better predictive value. Ease of use, good prognostic effect allows us to recommend Ad-DiaRem before bariatric treatment to. Duration of diabetes mellitus and number of hypoglycemic drugs taken seems to be one of the crucial factors in prognosis of DM remission.
Supporting agencies: The study was sponsored by state fund № 121031000362–3.
About the Authors
A. E. Neimark
Almazov National Medical Research Centre
Russian Federation
Russian Federation
Neimark Aleksandr Evgenevich – PhD, associate professor
eLibrary SPIN: 6554-3217
197341, 2 Akkuratova street, St. Petersburg
М. А. Molotkova
Almazov National Medical Research Centre
Russian Federation
Russian Federation
Molotkova Mariia Aleksandrovna – Research Assistant
197341, 2 Akkuratova street, St. Petersburg
Е. О. Makarova
Almazov National Medical Research Centre
Russian Federation
Russian Federation
Makarova Ekaterina Olegovna – Postgraduate student of the
Department of Endocrinology
197341, 2 Akkuratova street, St. Petersburg
M. I. Galchenko
FSBEC HE SPbSAU
Russian Federation
Russian Federation
Galchenko Maxim Ivanovich – senior lecturer
eLibrary SPIN: 8858-2916
196601, 2 Peterburskoe sh, Pushkin, Saint-Petersburg
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Review
For citations:
Neimark A.E., Molotkova М.А., Makarova Е.О., Galchenko M.I. The prognostic value of diarem and Ad-Diarem in patients with type 2 diabetes mellitus after bariatric surgery. Moscow Surgical Journal. 2022;(4):41-48. (In Russ.) https://doi.org/10.17238/2072-3180-2022-4-41-48
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