The impact of comorbidity on the risk of postoperative complications in patients with colon cancer

Introduction. Colon cancer is one of the most common malignancies and typically affects elderly patients with comorbidities. Comorbidities worsen the prognosis and increase the risk of postoperative complications.
Objective. To evaluate the diagnostic efficacy and practical value of the "Surgical risk assessment scale for comorbid colon cancer patients"
Materials and methods of research. A comparative study was conducted involving 260 comorbid patients with T3-4N0-1M0 colon adenocarcinoma undergoing surgical treatment in Botkin Hospital, Moscow from 2023 to 2025 years. Patients were divided into two groups based on the nature of the postoperative course – with or without complications. Statistical data analysis was performed using IBM SPSS software. Study results: the average score on the surgical risk assessment scale in patients with complicated postoperative course was 18,02 ± 2,89 and was significantly higher than in patients without complications – 16,7 ± 2,15, the pooled T-score was 3,309 (p = 0,001) (95 % CI: 0,38–2,102). The most significant indicators for assessing the risk of complications in the study group were the levels of hemoglobin, potassium, urea, and patient compliance (p < 0,05).
Treatment results. The developed "Scale for assessing the surgical risk in patients with comorbid colon cancer" demonstrated its diagnostic effectiveness AUC = 0,681 (p = 0,00). The rationale for using this scale is ensured by the implementation of the developed MedDocMobile mobile application in diagnostics. The use of this scale in clinical practice is promising due to the proven influence of modifiable risk factors on the course of the disease.

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