Immediate and Long-term Outcomes of Platelet-rich Plasma-assisted Lipofilling for Correction of Scar Deformities and Associated Complications Following Breast Cancer Surgery: A Single-Center Experience
https://doi.org/10.17238/2072-3180-2025-3-131-144
Abstract
Introduction. Postoperative cicatricial deformities and complications after breast reconstructive surgery following cancer treatment remain an urgent issue in modern surgery, necessitating the development and implementation of more effective correction methods.
The purpose of the study. To evaluate immediate and long-term outcomes of platelet-rich plasma (PRP)-assisted lipofilling in correcting postoperative scar deformities in breast cancer patients.
Materials and methods of research. The study included 30 patients who underwent reconstructive surgery followed by PRP-assisted lipofilling. The effectiveness of correction was evaluated using photographic and video documentation, the Vancouver Scar Scale (VSS), the Patient and Observer Scar Assessment Scale (POSAS), and the BREAST-Q questionnaire over a 12-month follow-up period.
Results of treatment. Immediate postoperative results demonstrated high aesthetic satisfaction among both patients and surgeons. PRP enhanced the vascularization and stability of transplanted fat tissues, ensuring stable long-term outcomes. No complications were identified during the year-long follow-up.
Conclusion. PRP-assisted lipofilling is an effective and safe method for correcting scar deformities following breast reconstruction. It significantly improves patients’ quality of life and ensures high aesthetic satisfaction.
About the Authors
Sh. Wang
I.M. Sechenov First Moscow State Medical University (Sechenov University)
Russian Federation
Russian Federation
Shuowen Wang – a postgraduate student at the G.I. Lukomsky Faculty of Surgery № 2
119435, Moscow, Trubetskaya Street, 8, building 2
M. P. Baranova
I.M. Sechenov First Moscow State Medical University (Sechenov University)
Russian Federation
Russian Federation
Baranova Madina Petrovna – PhD, Head of the Department of Breast and Skin Tumors, University Clinical Hospital № 4
Dovator Street, 15, p. 2, 119048, Moscow
X. Kong
Cancer Hospital, Chinese Academy of Medical Sciences
China
China
Xiangyi Kong – Doctor of Medicine, leading physician, Professor at the Breast Surgery Department of the Oncological Hospital
100021, 17 Panjiayuan Nanli, Beijing,
J. Zhang
Wuxi Branch Hospital of Nanjing University of Chinese Medicine
China
China
Jun Zhang – a Ph.D. Professor, Head of the Department of Breast and Thyroid Gland at the Wuxi Phyllial Hospital
214021, Zhongnan Power 8 (Hubinlu and Zhongnanlu Intersection), Wuxi
Zeting Zhou Чжоу
Pavlov First Saint Petersburg State Medical University
Russian Federation
Russian Federation
Zeting Zhou
6–8 Lva Tolstogo Street, Saint Petersburg, 197022
T. V. Khorobrykh
I.M. Sechenov First Moscow State Medical University (Sechenov University)
Russian Federation
Russian Federation
Khorobrykh Tatiana Vitalievna – MD, Professor, Head of the Department of Faculty Surgery № 2 named after G.I. Lukomsky, Director of the University Clinical Hospital № 4
8 Trubetskaya Street, building 2, Moscow, 119435
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Review
For citations:
Wang Sh., Baranova M.P., Kong X., Zhang J., Z., Khorobrykh T.V. Immediate and Long-term Outcomes of Platelet-rich Plasma-assisted Lipofilling for Correction of Scar Deformities and Associated Complications Following Breast Cancer Surgery: A Single-Center Experience. Moscow Surgical Journal. 2025;(3):131-144. (In Russ.) https://doi.org/10.17238/2072-3180-2025-3-131-144
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