Clinical and morphological aspects of the use of crushed maral antler slices in the treatment of aseptic soft tissue wounds

Introduction. The treatment of soft tissue wounds remains one of the urgent problems of modern surgery. Despite the wide variety of methods of their treatment and medications used to accelerate the course of regeneration processes, this problem remains unresolved.

The purpose of the study. To study the effect of crushed maral antler slices on the course of the wound process in the treatment of aseptic soft tissue wounds in an experiment.

Materials and methods of research. The study was conducted on the basis of the Burdenko Scientific Research Institute of Experimental Biology and Medicine on 90 Wistar rats in 3 groups. The effectiveness of the use was studied using objective, histological and histochemical, metric, including planimetric and morphometric techniques.

Results. Swelling and hyperemia of soft tissues were significantly relieved by 17,5 % and 14,8 % faster in the experimental group compared with the 2nd control group. The highest rate of reduction of the wound surface area is noted when using the proposed technique: on the 1st day, the area of the wound defect decreased by 40,54 %, by the 3rd day 70,97 %, by the 5th day 82,84 %, by the 7th day 90,84 %, on the 14th day of the study 99,41 %.

Conclusion. Analysis of the data from objective and morphological research methods has shown that the use of crushed slices of maral antlers leads to a complete restoration of the dermis of rat skin in the treatment of soft tissue wounds, activation of cellular elements, early cleansing and restoration of histoarchitectonics of the skin.

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