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The effect of negative pressure wound therapy after excision of a pilonidal sinus: a systematic review and meta-analysis

https://doi.org/10.17238/2072-3180-2024-4-221-227

Abstract

Introduction. Patients who have undergone surgery for a pilonidal cyst, in the majority, belong to a young, able-bodied category of the population, and it takes a long time for the wound to heal, which significantly affects the economic aspect of treatment and quality of life of patients. The use of negative pressure wound therapy (NPWT) after excision of the pilonidal cyst may shorten the duration of disability, decrease the length of postoperative hospital stay, reduce the cost of treatment, and ensuring the speedy return of patients to their usual lifestyle.

Materials and methods of research. The systematic review was conducted in accordance with PRISMA guidelines. The literature search was carried out in PubMed and eLibrary databases.

Results. The meta-analysis included 6 studies (151 patients who underwent negative pressure wound therapy after excision of the pilonidal cyst and 150 patients who underwent local conservative therapy). Statistically significant differences were found in the reduction of the time of wound healing after the pilonidal cyst excision. The wound healing time after excision was significantly lower (M = 15 days; p < .00001) in patients who received negative pressure wound therapy.

Conclusion. The use of negative pressure wound therapy in patients after pilonidal cyst excision reduces postoperative wound healing time.

About the Authors

I. N. Gorbunov
O.M. Filatov City Clinical Hospital No 15
Russian Federation

Gorbunov Ilya Nikolaevich – colorectal surgeon, 

111539, Veshnyakovskaya St., 23, Moscow



A. A. Balkarov
A.N. Ryzhikh National Medical Reserch Center of Coloproctology
Russian Federation

Balkarov Artem Anatolyevich – Candidate of Medical Sciences, oncologist, researcher,

123423, st. Salyama Adilya, 2, Moscow



M. A. Egorkin
O.M. Filatov City Clinical Hospital No 15; A.N. Ryzhikh National Medical Reserch Center of Coloproctology
Russian Federation

Mikhail Aleksandrovich Egorkin – Doctor of Medical Sciences, colorectal surgeon, senior researcher,

123423, st. Salyama Adilya, 2, Moscow



E. E. Bolkvadze
O.M. Filatov City Clinical Hospital No 15
Russian Federation

Bolkvadze Eteri Enverovna – Doctor of Medical Sciences, colorectal surgeon, Head of the Coloproctology Department,

111539, Veshnyakovskaya St., 23, Moscow



E. G. Rybakov
A.N. Ryzhikh National Medical Reserch Center of Coloproctology
Russian Federation

Rybakov Evgeny Gennadievich – Doctor of Medical Sciences, Professor of the Russian Academy of Sciences, oncologist, head of the oncoproctology department,

123423, st. Salyama Adilya, 2, Moscow



References

1. Levinson T., Sela T., Chencinski S. et al. Pilonidal Sinus Disease: A 10-Year Review Reveals Occupational Risk Factors and the Superiority of the Minimal Surgery Trephine Technique. Mil. Med, 2016, № 4, pp. 389– 394. https://doi.org/10.7205/MILMED-D-14-00729

2. Kober M.M et al. Treatment options for pilonidal sinus. J. Clin. Rev, 2018, № 4, рр. E23–E29.

3. Al-Khamis A., McCallum I., King P.M. et al. Healing by primary versus secondary intention after surgical treatment for pilonidal sinus. Cochrane Database Syst. Rev, 2010, № 1. https://doi.org/10.1002/14651858.CD006213.pub3

4. Moher D., Shamseer L., Clarke M. et al. Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015 statement. Syst Rev, 2015, № 1, рр.1. https://doi.org/10.1186/2046-4053-4-1

5. Zaytseva E.L., Tokmakova A.Yu. Vacuum therapy for chronic wounds. Diabetes mellitus, 2012, № 3, рр. 45–49. (In Russ.). https://doi.org/10.14341/2072-0351-6085

6. Obolenskiy V.N., Ermolov A.A. Negative pressure wound therapy in profilaxis and treatment of wound infections. Medical alphabet, 2017, № 5, рр. 49–52. (In Russ.).

7. Glass G. E. et al. Systematic review of molecular mechanism of action of negative‐pressure wound therapy. British Journal of Surgery, 2014, № 13, рр. 1627–36. https://doi.org/10.1002/bjs.9636

8. Morykwas M. J. et al. Vacuum-assisted closure: a new method for wound control and treatment: animal studies and basic foundation. Annals of plastic surgery, 1997, № 6, рр.553-562. https://doi.org/10.1097/00000637-199706000-00001

9. Schlosser K. A. et al. Management of Surgical Incisions Using Incisional Negative-Pressure Therapy. Plastic and Reconstructive Surger, 2019, № 1S, рр. 15S–20S. https://doi.org/10.1097/prs.0000000000005307

10. Ousey K., Milne J. Negative pressure wound therapy in the community: the debate. British journal of community nursing, 2009, № Sup 3, рр. S14–S20. https://doi.org/10.12968/bjcn.2014.19.sup3.s14

11. Li T. et al. Early application of negative pressure wound therapy to acute wounds contaminated with Staphylococcus aureus: an effective approach to preventing biofilm formation. Experimental and therapeutic medicine, 2016, № 3, рр. 769–776. https://doi.org/10.3892/etm.2016.3008

12. Zhou M. et al. Role of different negative pressure values in the process of infected wounds treated by vacuum‐assisted closure: an experimental study. International wound journal, 2013, № 5, рр. 508–515. https://doi.org/10.1111/j.1742-481X.2012.01008.x

13. Tuncel U., Erkorkmaz Ü., Turan A. Clinical evaluation of gauze‐ based negative pressure wound therapy in challenging wounds. International wound journal, 2013, № 2, рр. 152–158. https://doi.org/10.1111/j.1742-481X.2012.00955.x

14. Stinner D. J. et al. Silver dressings augment the ability of negative pressure wound therapy to reduce bacteria in a contaminated open fracture model. Journal of Trauma and Acute Care Surgery, 2011, рр. S147–S150. https://doi.org/10.1097/ta.0b013e318221944a

15. Liu Y. et al. Negative pressure wound therapy decreases mortality in a murine model of burn-wound sepsis involving Pseudomonas aeruginosa infection. PloS One, 2014, № 2, рр. 904–994. https://doi.org/10.1371/journal.pone.0090494

16. Lalliss S. J. et al. Negative pressure wound therapy reduces pseudomonas wound contamination more than Staphylococcus aureus. Journal of orthopaedic trauma, 2010, № 9, рр. 598–602. https://doi.org/10.1097/bot.0b013e3181ec45ba

17. Erba P. et al. Angiogenesis in wounds treated by microdeformational wound therapy. Annals of surgery, 2011, № 2, рр. 402–409. https://doi.org/10.1097/sla.0b013e31820563a8

18. Parades V. de, Bouchard D., Janier M. et al. Pilonidal sinus disease. J. Visc. Surg, 2013, № 4, рр. 237–247. https://doi.org/10.1016/j.jviscsurg.2013.05.006

19. Al-Salamah S. M., Hussain M. I., Mirza S. M. Excision with or without primary closure for pilonidal sinus disease. JPMA, 2007, № 8, рр. 388–391.

20. Biter L. U. et al. The use of negative-pressure wound therapy in pilonidal sinus disease: a randomized controlled trial comparing negativepressure wound therapy versus standard open wound care after surgical excision. Diseases of the Colon & Rectum, 2014, № 12, рр. 1406–1411. https://doi.org/10.1097/dcr.0000000000000240

21. Banasiewicz T., Bobkiewicz A., Borejsza-Wysocki M. Portable vac therapy improve the results of the treatment of the pilonidal sinus–randomized prospective study. Polish Journal of Surgery, 2013, № 7. https://doi.org/10.2478/pjs-2013-0056.

22. Gabor S. et al. Pilonidal Cyst Excision: Primary Midline Closure with versus without Closed Incision Negative Pressure Therapy. Plastic and Reconstructive Surgery Global Open, 2021, № 3, рр. 1–10. https://doi.org/10.1097/GOX.0000000000003473

23. Cherkasov MF et al. Effects of Vacuum Therapy on wound healing in sacrococcygeal area. Novosti Khirurgii, 2019, № 2, рр. 153–160. (In Russ.). https://doi.org/10.18484/2305-0047.2019.2.153

24. Rodoman GV et al. Postoperative rehabilitation of patients with epithelial coccygeal course with the use of local negative pressure. Vestnik vserossijskogo obshchestva specialistov po mediko-social&apos;noj ekspertize, reabilitacii i reabilitacionnoj industrii, 2017, рр. 63–70. (In Russ.).

25. Egorkin MA et Al. Negative pressure in treatment of pilonidal cyst: treatment experience. Khirurg, 2018, рр. 36–45. (In Russ.).

26. Perez D., Bramkamp M., Exe C., von Ruden C. et al. Modern wound care for the poor: a randomized clinical trial comparing the vacuum system with conventional saline-soaked gauze dressings. Am J Surg, 2010, № 1, рр. 14–20. https://doi.org/10.1016/j.amjsurg.2008.12.029


Review

For citations:


Gorbunov I.N., Balkarov A.A., Egorkin M.A., Bolkvadze E.E., Rybakov E.G. The effect of negative pressure wound therapy after excision of a pilonidal sinus: a systematic review and meta-analysis. Moscow Surgical Journal. 2024;(4):221-227. (In Russ.) https://doi.org/10.17238/2072-3180-2024-4-221-227

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ISSN 2072-3180 (Print)