Pulmonary cavitation in patients with Covid-19
https://doi.org/10.17238/2072-3180-2023-2-83-88
Abstract
Introduction. The causes of pulmonary cavities are known and described by many clinicians and radiologists, but in the past two years, against the background of SARS-CoV-2 viral pneumonia, unusual cavities in the lungs have appeared, differing both in radiological manifestations and clinically.
The purpose of the study. To present data on new, rare observations of the occurrence of lung cavitation in patients with Covid-19 and to determine the preferred treatment tactics.
Materials and methods. A study of the results of treatment of 9924 patients with Covid-19, aged 18 to 104 years, among whom 36 cases of lung cavitation were detected (20 women and 16 men). We note that cavitations can complicate the course of coronavirus infection, especially with subpleural localization.
Results. Of the 36 patients with covid cavitation, 4 died, which was 11,1 %, with a total mortality of 10 %. Long-term results were obtained, after cavitation, only in 5 patients out of 32 discharged, in the interval from 2 to 3 months: in 3 of them, multiple fibrous foci were detected during the control CT scan, in 2 – thin-walled "dry" cavities of small size.
Conclusion. Pulmonary cavitations at Covid-19 don't represent a serious problem, however they should be meant how the obvious causes of pheumothorax, a pnevmomediastinum and a piopnevmotoraks and also possible sources of pulmonary bleeding.
About the Authors
O. O. JasnogorodskijRussian Federation
Oleg Olegovich Yasnogorodsky, Doctor of Medical Sciences, Professor
Department of Faculty Surgery № 2 named after I. G. Lukomsky IKM
119991
st. Trubetskaya, 8, p. 2
Moscow
T. V. Khorobrykh
Russian Federation
Tatiana Vitalievna Khorobrykh, Doctor of Medical Sciences, Professor of the Russian Academy of Sciences, Head of the Department
Department of Faculty Surgery № 2 named after I. G. Lukomsky IKM
119991
Trubetskaya str., 8, p. 2
Moscow
F. N. Nasirov
Russian Federation
Fikret Nabievich Nasirov, Candidate of Medical Sciences, Associate Professor
Department of Faculty Surgery № 2 named after I. G. Lukomsky IKM
119991
st. Trubetskaya, 8, p. 2
Moscow
A. R. Patalova
Russian Federation
Alla Rubenovna Patalova, Candidate of Medical Sciences, Associate Professor
Department of Faculty Surgery № 2 named after I. G. Lukomsky IKM
119991
st. Trubetskaya, 8, p. 2
Moscow
Ju. A. Boblak
Russian Federation
Yulia Aleksandrovna Boblak, Assistant
Department of Faculty Surgery № 2 named after I. G. Lukomsky IKM
119991
st. Trubetskaya, 8, p. 2
Moscow
D. V. Kerner
Russian Federation
Denis Vladimirovich Kerner, chief physician
119991
st. 30th anniversary of Victory 6
Irkutsk Region
Bodaibo
I. A. Martynov
Russian Federation
Ivan Andreevich Martynov, 6th year student
119991
st. Trubetskaya, 8, p. 2
Moscow
N. R. Khusainova
Russian Federation
Nelli Rinatovna Khusainova, 4th year student
119991
st. Trubetskaya, 8, p. 2
Moscow
References
1. Amaral L.T., Beraldo G. L., Brito V. M., Rosa M. E., Matos M. J., Fonseca E. K. et al. Lung cavitation in COVID-19: co-infection complication or rare evolution? Einstein (São Paulo), 2020, № 18, eAI5822. URL: https://www.scielo.br/j/eins/a/yCffw5ZRrL9d3fKX8TmwNwQ/?lang=en&format=pdf
2. Chen Y., Chen W., Zhou J., Sun C., Lei Y. Large pulmonary cavity in COVID-19 cured patient case report. Annals of Palliative Medicine, 2021, May; № 10 (5), рр. 5786–5791.
3. Selvaraj V., Dapaah-Afriyie K. Lung cavitation due to COVID-19 pneumonia. BMJ Case Reports CP, 2020, Jul 6; № 13 (7), e237245.
4. Wang Y., Dong C., Hu Y., Li C., Ren Q. et al. Temporal changes of CT findings in 90 patients with COVID-19 pneumonia: a longitudinal study. Radiology, 2020. doi: 10.1148/radiol.2020200843
5. Chung M., Bernheim A., Mei X., Zhang N., Huang M. et al. CT imaging features of 2019 novel coronavirus (2019-nCoV). Radiology, 2020. doi: 10.1148/radiol.2020200230
6. Carotti M., Salaffi F., Sarzi-Puttini P., Agostini A., Borgheresi A. et al. Chest CT features of coronavirus disease 2019 (COVID-19) pneumonia: key points for radiologists. Radiol Med, 2020. doi: 10.1007/s11547-020-01237-4
7. Yao X. H., Li T. Y., He Z. C., Ping Y. F., Liu H. W. et al. A pathological report of three COVID-19 cases by minimal invasive autopsies. Zhonghua Bing Li Xue Za Zhi, 2020. doi: 10.3760/cma.j.cn112151-20200312-00193
8. Ternovoy S. K., Serova N. S., Belyaev A. S., Belyaeva K. A. COVID-19: first results of radiology in response to a new challenge. REJR, 2020; doi: 10.21569/2222-7415-2020-10-1-8-15
9. Zaid Zoumot, Maria-Fernanda Bonilla, Ali S. Wahla, Irfan Shafiq, Mateen Uzbeck, Rania M. El-Lababidi, Fadi Hamed, Mohamed Abuzakouk, Mahmoud ElKaissi. Pulmonary cavitation: an under-recognized late complication of severe COVID-19 lung disease. BMC Pulmonary Medicine, 2021, vol. 21, № 24, р. 4.
10. Zabozlaev F. G., Kravchenko E. V., Gallyamova A. R., Letunovsky N. N. Pulmonary pathology of the new coronavirus disease (COVID-19). The preliminary analysis of post-mortem findings. Journal of Clinical Practice, 2020. vol. 11, № 2, pp. 21–37.
11. Hirmanov V. N. COVID-19 as a systemic disease. Clinical Pharmacology and Therapy, 2021, № 1. (In Russ.)
12. Berrin Erok, Kenan Kibici, Ali Onder Atka. Pulmonary cavitation in Covid-19 pneumonia; is it primary or secondary? African Journal of Respiratory Medicine, 2020. vol. 15, № 1.
13. Varga Z. et al. Endothelial cell infection and endotheliitis in COVID-19. Lancet, 2020. doi: 10.1016/S0140-6736(20)30937-5
14. Sun, R., et al. Mediastinal emphysema, giant bulla, and pneumothorax developed during the course of COVID-19 pneumonia. Korean J. Radiol, 2020, May; № 21 (5), рр. 541–544.
15. Selvaraj V. Pulmonary Cavitation: A Rare Complication of Covid-19 Pneumonia. Medical Reports and Case Studies, 2021, Vol. 6, Issue S1, рр. 196.
Review
For citations:
Jasnogorodskij O.O., Khorobrykh T.V., Nasirov F.N., Patalova A.R., Boblak J.A., Kerner D.V., Martynov I.A., Khusainova N.R. Pulmonary cavitation in patients with Covid-19. Moscow Surgical Journal. 2023;(2):83-88. (In Russ.) https://doi.org/10.17238/2072-3180-2023-2-83-88