Сurrent methods of treating patients with large midline postoperative ventral hernias
https://doi.org/10.17238/2072-3180-2025-3-190-197
Abstract
Introduction. Ventral hernias are a common postoperative complication, particularly following midline laparotomy, with an incidence exceeding 30%. Surgical treatment presents significant challenges due to pronounced anatomical abnormalities, fibrotic tissue changes, severe comorbidities, and the complexity of planning the extent and nature of reconstructive interventions during preoperative preparation. In recent years, new approaches to treating large postoperative midline ventral hernias (POVH) have emerged, requiring systematic analysis and evaluation of their effectiveness.
Objective. To conduct a systematic analysis of modern surgical techniques for treating large POVH, including various separation-based repair techniques, and to assess the efficacy of preoperative botulinum toxin type A (BTA) in the comprehensive management of this condition
Results. A reduction in postoperative complications and recurrence rates was observed with the use of posterior separation-based repair (Transversus Abdominis Muscle Release, TAR). Preoperative BTA administration in these patients contributed to an average increase in lateral abdominal wall muscle mobility of 3.2–4.7 cm on each side, facilitating effective closure of midline defects and reducing the extent of separation-based repair.
Conclusion. Preoperative BTA administration in patients with large midline hernias allows for a reduction in the extent of separation-based repair, thereby decreasing surgical trauma and the risk of compartment syndrome.
About the Authors
H. OthmanRussian Federation
Othman Hassan – Phd student
117198, Miklukho-Maklaj str., 6, Moscow
M.K.M. Al-Ariki
Russian Federation
Al-Ariki Malik Kiaed Mohammed – Candidate of Medical Sciences, assistant professor
117198, Miklukho-Maklaj str., 6, Moscow , 8 977 685 10 28
M. A. Chinikov
Russian Federation
Chinikov Maxim Alekseevich – Doctor of Medical Sciences, professor
117198, Miklukho-Maklaj str., 6, Moscow
References
1. Jairam A.P., Timmermans L., Eker H.H., Pierik REGJM, van Klaveren D., Steyerberg E.W., Timman R., van der Ham A.C., Dawson I., Charbon J.A., Schuhmacher C., Mihaljevic A., Izbicki J.R., Fikatas P., Knebel P., Fortelny R.H., Kleinrensink G.J., Lange J.F., Jeekel H.J. 2-year follow-up of a multicentre, double-blind, randomised controlled trial. Lancet, 2017, № 390 (10094), pp. 567–576.
2. Oprea V., Toma M., Grad O., Bucuri C., Pavel P., Chiorescu S., Moga D. The outcomes of open anterior component separation versus posterior component separation with transversus abdominis release for complex incisional hernias: a systematic review and meta-analysis. Hernia, 2023, № 27 (3), pp. 503–517.
3. Toma M., Oprea V., Grad O., Staines H., Bucuri C.E., Andercou O., Gherghinescu M., Molnar C. Early outcomes of open anterior versus posterior components separation with transversus abdominis release for large median incisional hernias: a retrospective stepwise analysis. Hernia, 2024, № 28 (3), pp. 803–813.
4. Dries P., Verstraete B., Allaeys M., Van Hoef S., Eker H., Berrevoet F. Anterior versus posterior component separation technique for advanced abdominal wall reconstruction: a proposed algorithm. Hernia, 2024, № 28 (3), pp. 895–904.
5. Riediger H., Köckerling F. Limitations of Transversus Abdominis Release (TAR)-Additional Bridging of the Posterior Layer And/Or Anterior Fascia Is the Preferred Solution in Our Clinical Routine If Primary Closure is Not Possible. J Abdom Wall Surg, 2024, № 17 (3), рр. 12780. https://doi.org/10.3389/jaws.2024.12780
6. Polyakov A.A., Solovyev A.O., Kasterina A.V., Zapalatskaya O.V., Mikhin I.V., Yagupov P.P. Unilateral TAR-plasty - beyond the semilunar line. National Surgical Congress with International Participation and XIV Congress of Surgeons of Russia. Almanac of the Vishnevsky Institute of Surgery, Collection of abstracts, 2022 № 1, pp. 86–87. (In Russ.)
7. Vogel R., Heinzelmann F., Büchler P., Mück B. Robot-Assisted Extraperitoneal Ventral Hernia Repair-Experience From the First 160 Consecutive Operations With Lateral eTEP and eTAR Techniques. J Abdom Wall Surg., 2024, № 22 (3), РР. 13055. https://doi.org/10.3389/jaws.2024.13055
8. Wegdam J.A., Thoolen J.M.M., Nienhuijs S.W., de Bouvy N., de Vries Reilingh T.S. Systematic review of transversus abdominis release in complex abdominal wall reconstruction. Hernia, 2019, № 23 (1), pp. 5–15.
9. Christopher A.N., Fowler C., Patel V., Mellia J.A., Morris M.P., Broach R.B., Fischer J.P. Bilateral transversus abdominis release: Complex hernia repair without sacrificing quality of life. Am J Surg., 2022, № 223 (2), pp. 250–256.
10. Rabie M., Abdelnaby M., Morshed M., Shalaby M. Posterior component separation with transversus abdominis muscle release versus meshonly repair in the treatment of complex ventral-wall hernia: a randomized controlled trial. BMC Surg., 2022, 20; № 22 (1), РР. 346. https://doi.org/10.1186/s12893-022-01794-7
11. Nguyen T., Kunes K., Crigler, C., Ballecer C. Robotic transversus abdominis release for ventral hernia repairs. International Journal of Abdominal Wall and Hernia Surgery, 2022, № 5 (3), pp. 103–109.
12. Kolygin A.V., Vyborny M.I., Petrov D.I. Use of the Da Vinci robotic system in hernia surgery: Clinical experience. Surgery. N.I. Pirogov Journal , 2024, № 3, pp. 14–20. (In Russ.)
13. Fry B.T., Howard R.A., Thumma J.R., Norton E.C., Dimick J.B., Sheetz K.H. Surgical Approach and Long-Term Recurrence After Ventral Hernia Repair. JAMA Surg., 2024, № 1, 159 (9), pp. 1019–1028.
14. Cakmak M., Caglayan F., Somuncu S., Leventoglu A., Ulusoy S., Akman H., Kaya M. Effect of paralysis of the abdominal wall muscles by botulinum A toxin to intraabdominal pressure: an experimental study. J Pediatr Surg., 2006, № 41 (4), pp. 821–825.
15. Ibarra-Hurtado T.R., Nuño-Guzmán C.M., Echeagaray-Herrera J.E., Robles-Vélez E., de Jesús González-Jaime J. Use of botulinum toxin type a before abdominal wall hernia reconstruction. World J Surg., 2009, № 33 (12), pp. 2553–2556.
16. Zielinski M.D., Goussous N., Schiller H.J., Jenkins D. Chemical components separation with botulinum toxin A: a novel technique to improve primary fascial closure rates of the open abdomen. Hernia, 2013, № 17 (1), pp. 101–107.
17. Timmer A.S., Claessen J.J.M., Atema J.J., Rutten M.V.H., Hompes R., Boermeester M.A. A systematic review and meta-analysis of technical aspects and clinical outcomes of botulinum toxin prior to abdominal wall reconstruction. Hernia, 2021, № 25 (6), pp. 1413–1425.
18. Jacombs A., Elstner K., Rodriguez-Acevedo O., Read J.W., HoShon K., Wehrhahn M., Salazar K., Ibrahim N. Seven years of preoperative BTA abdominal wall preparation and the Macquarie system for surgical management of complex ventral hernia. Hernia, 2022, № 26 (1), pp. 109–121.
19. Wegdam J.A., de Vries Reilingh T.S., Bouvy N.D., Nienhuijs S.W. Prehabilitation of complex ventral hernia patients with Botulinum: a systematic review of the quantifiable effects of Botulinum. Hernia, 2021, № 25 (6), pp. 1427–1442.
20. Claessen J.J.M., Timmer A.S., Hemke R., Atema J.J., Hompes R., Boermeester M.A., Rutten M.V.H. A computed tomography study investigating the effects of botulinum toxin injections prior to complex abdominal wall reconstruction. Hernia, 2023, № 27 (2), pp. 281–291.
21. Chávez-Tostado K. V., Cárdenas-Lailson L. E., Pérez-Trigos H. Resultado de la aplicación preoperatoria de toxina botulínica A en el tratamiento de hernias incisionales gigantes. Rev. Hispanoamer de Hernia, 2014, № 2, pp. 145–151.
22. Bueno-Lledó J., Carreño-Saenz O., Torregrosa-Gallud A., Pous-Serrano S. Preoperative Botulinum Toxin and Progressive Pneumoperitoneum in Loss of Domain Hernias-Our First 100 Cases. Front Surg., 2020, № 28, рр. 7:3. https://doi.org/10.3389/fsurg.2020.00003
23. Elstner K.E., Read J.W., Saunders J., Cosman P.H., Rodriguez-Acevedo O., Jacombs A.S.W., Martins R.T., Ibrahim N. Selective muscle botulinum toxin A component paralysis in complex ventral hernia repair. Hernia, 2020, № 24 (2), pp. 287–293.
24. Ibarra-Hurtado T.R., Nuño-Guzmán C.M., Echeagaray-Herrera J.E., Robles-Vélez E., de Jesús González-Jaime J. Use of botulinum toxin type a before abdominal wall hernia reconstruction. World J Surg., 2009, № 33 (12), pp. 2553–2556.
25. Smoot D., Zielinski M., Jenkins D., Schiller H. Botox A injection for pain after laparoscopic ventral hernia: a case report. Pain Med., 2011, № 12 (7), pp. 1121–1123.
26. Zendejas B., Khasawneh M.A., Srvantstyan B., Jenkins D.H., Schiller H.J., Zielinski M.D. Outcomes of chemical component paralysis using botulinum toxin for incisional hernia repairs. World J Surg., 2013, № 37 (12), pp. 2830–2837.
27. Pous-Serrano S., Bueno-Lledó J., García-Pastor P., Carreño-Sáenz O., Pareja-Ibars V., Bonafé-Diana S., Gea-Moreno A.M., Martínez-Hoed J. Members of the Sección de Pared Abdominal de la Asociación Española de Cirujanos. Use of botulinum toxin type A in the prehabilitation of abdominal wall musculature for hernia repair: a consensus proposal. Cir Esp (Engl Ed), 2024, № 102 (7), pp. 391–399.
28. Catalán-Garza V, Peña-Soria M.J., Sáez-Carlin P., Cabeza-Gómez J.J., García-Fernández A.,Torres-Garcia A.J. Long-term results of botulinum toxin type A in complex abdominal wall repair and review of the literature. Updates Surg., 2020, № 72 (4), pp. 1201–1206.
29. Deerenberg E.B., Elhage S.A., Raible R.J., Shao J.M., Augenstein V.A., Heniford B.T., Lopez R. Image-guided botulinum toxin injection in the lateral abdominal wall prior to abdominal wall reconstruction surgery: review of techniques and results. Skeletal Radiol, 2021, № 50 (1), pp. 1–7.
30. Parshikov V.V., Konovalova E.A., Teremov S.A. Initial experience of using botulinum toxin type A, laparoscopy, and posterior component separation in the surgical treatment of patients with large incisional hernias and loss of domain. Sovremennye problemy nauki i obrazovaniya, 2024, № 4. (In Russ.) https://doi.org/10.17513/spno.33532
Review
For citations:
Othman H., Al-Ariki M., Chinikov M.A. Сurrent methods of treating patients with large midline postoperative ventral hernias. Moscow Surgical Journal. 2025;(3):190-197. (In Russ.) https://doi.org/10.17238/2072-3180-2025-3-190-197