Low-temperature Argon Plasma: from the Biophysical Foundations for practical application in clinical medicine
https://doi.org/10.17238/2072-3180-2025-3-178-189
Abstract
Introduction. Low-temperature argon plasma (LTAP) is increasingly being used in medicine due to its antimicrobial, anti-inflammatory, and regenerative properties. Objective. To compare the energy parameters of ultraviolet radiation emitted by the "Plazmoran" and "PLAZON" devices to evaluate their effectiveness in clinical practice.
Materials and Methods. The study was conducted using two devices: – "Plazmoran" (operates on argon) – "PLAZON" (uses air). The energy illumination of UV radiation was measured at distances of 10, 15, and 20 cm. For "Plazmoran," mode B2 was used; for "PLAZON," the maximum mode was applied.
Results. "Plazmoran" demonstrated 5 times higher illumination in the UV-C range compared to "PLAZON." This is attributed to the use of argon, which ensures stable recombinant radiation. With increasing distance, the effectiveness decreases due to the absorption of UV radiation by oxygen in the air. Clinical data confirm the efficacy of LTAP in treating wounds, burns, dermatological diseases, and blast injuries in children. The application of plasma promotes faster wound healing, reduces inflammation, and activates tissue regeneration.
Conclusion. The "Plazmoran" device has higher energy characteristics and more stable effects, making it preferable for clinical use. The use of argon eliminates unwanted chemical reactions and enhances therapeutic efficacy. The obtained results confirm the promising prospects for further integration of LTAP technologies into medical practice.
About the Authors
A. B. ZemlyanoiRussian Federation
Zemlyanoi Alexander Borisovich – Doctor of Medical Sciences, Professor, Leading Researcher
1, territory 3, Novy Settlement, Krasnogorsk, Moscow Region, 143420
M. A. Evseev
Russian Federation
Evseev Maxim Alexandrovich – Doctor of Medical Sciences, Professor, Deputy Head of Scientific Work
1, territory 3, Novy Settlement, Krasnogorsk, Moscow Region, 143420
P. S. Markevich
Russian Federation
Markevich Pavel Sergeyevich – Candidate of Medical Sciences, Lieutenant Colonel of the Medical Service, Head of the 63rd Department of Purulent Surgery
1, territory 3, Novy Settlement, Krasnogorsk, Moscow Region, 143420
A. V. Filippov
Russian Federation
Filippov Alexander Viktorovich – Candidate of Medical Sciences, Lieutenant Colonel of the Medical Service, Chief Surgeon
1, territory 3, Novy Settlement, Krasnogorsk, Moscow Region, 143420
R. N. Dolgikh
Russian Federation
Dolgikh Ruslan Nikolaevich – Candidate of Medical Sciences, Colonel of the Medical Service, Surgeon
1, territory 3, Novy Settlement, Krasnogorsk, Moscow Region, 143420
Yu. A. Tyukalov
Russian Federation
Tyukalov Yuri Alexandrovich – Surgeon of the 12th Department of Abdominal Surgery
1, territory 3, Novy Settlement, Krasnogorsk, Moscow Region, 143420
R. T. Nalbandian
Russian Federation
Nalbandian Ruben Tigranovich – Candidate of Medical Sciences, Head of the Department of Wounds and Wound Infections
22 Bolshaya Polyanka str., Moscow, 119180
T. A. Zelenina
Russian Federation
Zelenina Tatiana Aleksandrovna – Candidate of Medical Sciences, Associate Professor, endocrinologist, Senior lecturer at the TUV-1 Department with a course in endocrinology
A. A. Gromova
Russian Federation
Gromova Anastasia Alexandrovna – Surgeon
22 Bolshaya Polyanka str., Moscow, 119180
N. G. Gerasimov
Russian Federation
Gerasimov Nikita Gennadievich – Major of the Medical Service, Surgeon of the 63rd Department of Purulent Surgery
1, territory 3, Novy settlement, Krasnogorsk, Moscow Region, 143420
I. A. Pesterev
Russian Federation
Pesterev Ivan Aleksandrovich – Traumatologist of the 63rd Department of Purulent Surgery
1, territory 3, Novy settlement, Krasnogorsk, Moscow Region, 143420
D. S. Koretsky
Russian Federation
Koretsky Danil Sergeevich – Traumatologist of the 63rd Department of Purulent Surgery
1, territory 3, Novy settlement, Krasnogorsk, Moscow Region, 143420
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Review
For citations:
Zemlyanoi A.B., Evseev M.A., Markevich P.S., Filippov A.V., Dolgikh R.N., Tyukalov Yu.A., Nalbandian R.T., Zelenina T.A., Gromova A.A., Gerasimov N.G., Pesterev I.A., Koretsky D.S. Low-temperature Argon Plasma: from the Biophysical Foundations for practical application in clinical medicine. Moscow Surgical Journal. 2025;(3):178-189. (In Russ.) https://doi.org/10.17238/2072-3180-2025-3-178-189