Changes in hormonal background in the immediate postoperative period in women with penetrating gunshot wounds of the small pelvis
https://doi.org/10.17238/2072-3180-2024-2-70-76
Abstract
Introduction. The problem of traumatic injuries of the pelvic girdle, until now still does not lose its relevance.
The purpose of the study. To study changes in hormonal background in women with penetrating gunshot wounds of the small pelvis in the immediate postoperative period.
Materials and methods of research. Forty female patients from the civilian population who were treated for penetrating gunshot wounds of the small pelvis received as a result of localized combat operations were selected. The mean age was 36±4 years. The immediate postoperative period depends on the time factor occupying the interval from the moment of wounding to the surgical intervention. Based on this, we formed two clinical groups of 20 people each. The first group (A) included the wounded, whose time interval did not exceed 60 min, and the second group (B) included the wounded, whose time interval exceeded 60 min.
Results. Starting from the first day after surgery, the increase of hormones in the two groups differed: in group A, where help was provided more quickly, respectively, the traumatic factor was less, the amount of hormones increased compared to normal values, however, compared to group B.
Conclusion. The study shows that pelvic gunshot wounds in women lead to changes in the hormonal background that depend on the time elapsed from the time of wounding to the start of surgical treatment and vary depending on the day elapsed since the surgical intervention was performed.
About the Authors
V. V. MaslyakovRussian Federation
Maslyakov Vladimir Vladimirovich – Doctor of Medicine Sciences, Professor, Professor, Department of Mobilization Preparation of Public Health and Disaster Medicine; Doctor of Medicine Sciences, Professor, Department of Surgical Diseases
410012, Bolshaya Kazachya St., 112, Saratov;
410012, Verkhny Market St., Bldg. 10, Saratov
S. V. Kapralov
Russian Federation
Kapralov Sergey Vladimirovich – Doctor of Medicine Sciences, associate professor, Head of the Department of Faculty Surgery and Oncology
410012, Bolshaya Kazachya St., 112, Saratov
S. А. Sidelnikov
Russian Federation
Sidelnikov Sergey Alekseevich – Doctor of Medicine Sciences, associate professor, Head of the Department of Mobilization Preparation of Public Health and Disaster Medicine
410012, Bolshaya Kazachya St., 112, Saratov
М. А. Polidanov
Russian Federation
Polidanov Maxim Andreevich – research department specialist, assistant of the Department of Biomedical Disciplines; Postgraduate student of the Department of Surgical Diseases
198099, Kalinina St., 8, bld. 2, lit. A, Saint Petersburg4
410012, Verkhny Market St., Bldg. 10, Saratov
S. Е. Uryadov
Russian Federation
Uryadov Sergey Evgenyevich – Doctor of Medicine Sciences, Associate Professor, Associate Professor of the Department of Surgical Diseases
410012, Bolshaya Kazachya St., 112, Saratov
V. G. Barsukov
Russian Federation
Barsukov Vitaly Gennadievich – Candidate of Medical Sciences, Assistant of the Department of Faculty Surgery and Oncology; Candidate of Medical Sciences, senior lecturer of the Department of Surgical Diseases
410012, Bolshaya Kazachya St., 112, Saratov;
410012, Verkhny Market St., Bldg. 10, Saratov
А. V. Parshin
Russian Federation
Parshin Alexey Vladimirovich – Candidate of Medical Sciences, Associate Professor, Associate Professor of the Department of Obstetrics and Gynecology, Faculty of Medicine
410012, Bolshaya Kazachya St., 112, Saratov
К. А. Volkov
Russian Federation
Volkov Kirill Andreevich – 2-nd year student of the Faculty of Medicine
410012, Bolshaya Kazachya St., 112, Saratov
V. S. Marchenko
Russian Federation
Marchenko Vladislav Sergeevich – resident physician of the Department of Urology
410012, Bolshaya Kazachya St., 112, Saratov
G. G. Mezirov
Russian Federation
Mezirov Georgiy Georgievich – resident physician of the Department of Urology
410012, Bolshaya Kazachya St., 112, Saratov
References
1. Aliyev S.A., Aliyev T.G. Surgical treatment of gunshot wounds of the chest and abdomen. Bulletin of the National Medical and Surgical Center named after N.I. Pirogov, 2023, vol. 18, № 3, рр. 51–57. (In Russ.)
2. Borovoy I.S., Gerusov M.A., Agarkov A.V., Lobanov G.V. Surgical treatment of gunshot wounds of the pelvis and hip joint. Polytrauma, 2023, № 1, рр. 39–44. (In Russ.)
3. Maslyakov V.V., Salov I.A., Sidelnikov S.A., Uryadov S.E., Parshin A.V., Barsukov V.G., Polidanov M.A., Papadopoulos H.D., Petrich A.V. Optimization of surgical treatment of gunshot wounds of the pelvis with damage to the internal genitalia in women. Polytrauma, 2023, № 4, рр. 13–19. (In Russ.)
4. Maslyakov V.V., Salov I.A., Sidelnikov S.A., Barachevsky Y.E., Parshin A.V., Polidanov M.A. Characterization of the types of first aid for pelvic wounds in women received in a local military conflict. Emergency Medical Aid. Journal named after N.V. Sklifosovsky, 2023, Vol. 12, № 4, рр. 601–606. (In Russ.)
5. Bocharov S.N., Kulinsky V.I., Vinogradov V.G., Lebed M.L., Kirpichenko M.G., Gumanenko V.V., Lepekhova S.A., Rodionova L.V. Changes in metabolic activity and hormonal profile after multiple skeletal trauma in an experiment. Baikal Medical Journal, 2011, № 2, рр. 90–93. (In Russ.)
6. Bocharov S.S., Vinogradov V.G., Lebed M.L., Gumanenko V.V., Golubev S.S., Lepekhova S.A. The effect of prescribing dexamethasone and adrenaline on changes in morphometric parameters of internal organs after multiple skeletal trauma in an experiment. Polytrauma, 2015, № 2, рр. 77–82. (In Russ.)
7. Kozlova A.I., Kozlova M.A. Cortisol as a stress marker. Human Physiology, 2014, № 2, рр. 123. (In Russ.)
8. Semenov A.V., Sorokovikov V.A. Scales for assessing the severity and predicting the outcome of injuries. Polytrauma, 2016, № 2, рр. 80–90. (In Russ.)
9. Maslyakov V.V., Sidelnikov S.A., Barachevsky Y.E., Kurkin K.G., Pimenova A.A., Polidanov M.A., Polikarpov D.A., Barulina M.A. Mass simultaneous admission of victims in emergency situations to medical treatment organizations: organizational problems and possible ways of their solution. Disaster Medicine, 2023, № 2, рр. 51–55. (In Russ.)
10. Selivanova A.V., Yakovlev V.N., Moroz V.V. [et al.] Hormonal and Metabolic Changes in Critically Ill Patients. General Reanimatology, 2012, vol. 8, № 5, рр. 70–76. (In Russ.)
Review
For citations:
Maslyakov V.V., Kapralov S.V., Sidelnikov S.А., Polidanov М.А., Uryadov S.Е., Barsukov V.G., Parshin А.V., Volkov К.А., Marchenko V.S., Mezirov G.G. Changes in hormonal background in the immediate postoperative period in women with penetrating gunshot wounds of the small pelvis. Moscow Surgical Journal. 2024;(2):70-76. (In Russ.) https://doi.org/10.17238/2072-3180-2024-2-70-76