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Coronary artery bypass grafting in patients with heart failure with preserved ejection fraction

https://doi.org/10.17238/2072-3180-2025-3-69-78

Abstract

Introduction. Objective. To assess the intraoperative and postoperative course in patients with heart failure with preserved ejection fraction (HFpEF) undergoing coronary artery bypass grafting (CABG), and to compare their outcomes with those of patients with reduced ejection fraction (HFrEF) and patients without signs of heart failure (HF).
Materials and methods. A total of 154 patients with coronary artery disease were included in the study and divided into three groups: HFpEF (n = 62), HFrEF (n = 54), and no HF (n = 38). All patients underwent isolated CABG with the use of cardiopulmonary bypass. Intraoperative parameters, incidence of rhythm disturbances, and early postoperative outcomes were analyzed.
Results. Patients with HFpEF had a higher incidence of postoperative atrial fibrillation (35,5 % vs. 15,8 % in patients without HF; p = 0,040), longer duration of mechanical ventilation (6,5 [5,1–8,0] h vs. 5,5 [4,0–6,5] h; p = 0,003), and longer hospital stay (11 [8,25–15] days vs. 9 [8–10,75] days; p = 0,013). There was also a trend toward a lower rate of spontaneous rhythm recovery after reperfusion in the HFpEF group.
Conclusions. HFpEF significantly affects the postoperative course in patients undergoing CABG. The increased risk of complications and prolonged recovery period highlight the need for an individualized approach to managing this patient population.

About the Authors

N. K. Klyshko
Far East Federal University Medical Center
Russian Federation

Klyshko Nikita Konstantinovich – cardiovascular surgeon 

25, Ajax Village, Russian Island, Vladivostok, Primorsky Krai, tel. +7 (914) 654-42-49 



N. A. Kunnazarova
Far East Federal University Medical Center
Russian Federation

Kunnazarova Nargiza Amangeldi kyzy – cardiovascular surgery resident

25, Ajax Village, Russian Island, Vladivostok, Primorsky Krai



V. A. Sorokin
Pacific State Medical University
Russian Federation

Sorokin Vitaly Alexandrovich – Doctor of Medical Sciences, cardiovascular surgeon, professor of institute of surgery

25, Ajax Village, Russian Island, Vladivostok, Primorsky Krai



References

1. Teramoto K., Teng T. H. K., Chandramouli C. et al. Epidemiology and Clinical Features of Heart Failure with Preserved Ejection Fraction. Cardiac Failure Review, 2022, vol. 8, рр. e27. https://doi.org/10.15420/cfr.2022.06

2. Vasan R. S., Xanthakis V., Lyass A. et al. Epidemiology of Left Ventricular Systolic Dysfunction and Heart Failure in the Framingham Study.: JACC: Cardiovascular Imaging, 2018, vol. 11(1), рр. 1–11. https://doi.org/10.1016/j.jcmg.2017.08.007

3. Oshchepkova E. V., Lazareva N. V., Saltykova D. F. et al. First results of the Russian registry of heart failure. Cardiology, 2015, № 55(5), рр. 22–28. (In Russ.) https://doi.org/10.18565/cardio.2015.5.22-28

4. Hwang S.-J., Melenovsky V., Borlaug B. A. Implications of coronary artery disease in heart failure with preserved ejection fraction. Journal of the American College of Cardiology, 2014, vol. 63(25, Pt A), рр. 2817–2827. https://doi.org/10.1016/j.jacc.2014.03.034

5. Nguyen L. S., Baudinaud P., Brusset А. et al. Heart failure with preserved ejection fraction as an independent risk factor of mortality after cardiothoracic surgery. The Journal of Thoracic and Cardiovascular Surgery, 2018, vol. 156(1), рр. 188–193.e2. https://doi.org/10.1016/j.jtcvs.2018.02.011

6. Reddy Y. N. V., Carter R. E., Obokata M. et al. A Simple, EvidenceBased Approach to Help Guide Diagnosis of Heart Failure With Preserved Ejection Fraction. Circulation, 2018, vol. 138(9), рр. 861–870. https://doi.org/10.1161/circulationaha.118.034646

7. Benjamin E. J., Muntner P., Alonso A. et al. Heart Disease and Stroke Statistics-2019 Update : A Report From the American Heart Association. Circulation, 2019, vol. 139(10), рр. e56–e528. https://doi.org/10.1161/cir.0000000000000659

8. Ponikowski P., Voors A. A., Anker S. D. et al. 2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure. European Heart Journal, 2016, vol. 37(27), рр. 2129–2200. https://doi.org/10.1093/eurheartj/ehw128

9. Dalén M., Lund L. H., Ivert T.et al. Survival After Coronary Artery Bypass Grafting in Patients With Preoperative Heart Failure and Preserved vs Reduced Ejection Fraction. JAMA Cardiology, 2016, vol. 1(5), рр. 530– 538. https://doi.org/10.1001/jamacardio.2016.1465

10. Denault A. Y., Couture P., Buithieu J. et al. Left and right ventricular diastolic dysfunction as predictors of difficult separation from cardiopulmonary bypass. Canadian Journal of Anesthesia, 2006, vol. 53(10), рр. 1020–1029. https://doi.org/10.1007/bf03022532

11. Lam C. S. P., Rienstra M., Tay W. T. et al. Atrial Fibrillation in Heart Failure With Preserved Ejection Fraction : Association With Exercise Capacity, Left Ventricular Filling Pressures, Natriuretic Peptides, and Left Atrial Volume. JACC: Heart Failure, 2017, vol. 5(2), рр. 92–98. https://doi.org/10.1016/j.jchf.2016.10.005

12. Nekrasova T.V., Perepech N.B. Features of Cardiac Rhythm Disorders in Patients with Chronic Heart Failure and Preserved Ejection Fraction. Bulletin of Arrhythmology, 2015, № 81, pp. 15–21. (In Russ.)


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For citations:


Klyshko N.K., Kunnazarova N.A., Sorokin V.A. Coronary artery bypass grafting in patients with heart failure with preserved ejection fraction. Moscow Surgical Journal. 2025;(3):68-77. (In Russ.) https://doi.org/10.17238/2072-3180-2025-3-69-78

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ISSN 2072-3180 (Print)