Bariatric surgery in the treatment of morbid obesity ana chronic kidney disease

   Introduction. Chronic kidney disease (CKD) is a serious disease, the most common causes of which are obesity, diabetes, metabolic disorders, cardiovascular disease, and others. Approximately 10 % of adults worldwide have chronic kidney disease, resulting in 1,2 million deaths each year. Epidemiological studies have determined the association of obesity with the development of end-stage chronic kidney disease and the risk of hemodialysis sessions.
   The purpose of the study. To evaluate the effectiveness of bariatric surgery in terms of reducing the risks of end-stage chronic kidney disease, as well as improving the quality of life in patients on hemodialysis who underwent surgery for obesity.

   Materials and methods. Literature reviews and articles describing the experience of bariatric surgery in patients with chronic kidney disease and patients on hemodialysis.
   Results. The effectiveness of bariatric interventions in the treatment of morbid obesity and metabolic syndrome has been undeniable and proven. The possibility of treating patients with progressive renal failure in patients with obesity through surgical methods is relevant and discussed. First of all, bariatric surgery.
   Conclusion. Bariatric surgery significantly improves the quality of life and reduces the risk of mortality in patients with chronic kidney disease of any stage.

1. Kalantar-Zadeh K., Jafar T. H., Nitsch D., Neuen B. L., & Perkovic V. Chronic kidney disease. The Lancet, 2021, № 398 (10302), pp. 786–802. doi: 10.1016/s0140-6736(21)00519-5

2. Ladhani M., Craig J. C., Irving M., Clayton P. A., & Wong G. Obesity and the risk of cardiovascular and all-cause mortality in chronic kidney disease: a systematic review and meta-analysis. Nephrology Dialysis Transplantation, 2016, № 32 (3), March 2017, pp. 439–449, doi: 10.1093/ndt/gfw075

3. Friedman A. N. Obesity in patients undergoing dialysis and kidney transplantation. Adv Chronic Kidney, 2013, № 20 (2), pp. 128–134. doi: 10.1053/j.ackd.2012.10.009

4. Wang Y., Chen X., Song Y., Caballero B. & Cheskin L. J. Association between obesity and kidney disease: a systematic review and meta-analysis. Kidney international, 2008, № 73 (1), pp. 19–33. doi: 10.1038/sj.ki.5002586

5. Buchwald H., Avidor Y., Braunwald E., Jensen M. D., Pories W., Fahrbach K., Schoelles K. Bariatric surgery: a systematic review and meta-analysis. JAMA, 2004, № 292 (14), pp. 1724–1737. doi: 10.1001/jama.292.14.1724

6. Kramer H., Luke A. Obesity and kidney disease: a big dilemma. Current opinion in nephrology and hypertension, 2007, № 16 (3), pp. 237–241. doi: 10.1097/MNH.0b013e32803578e4

7. Coresh J., Selvin E., Stevens L. A., Manzi J., Kusek J. W., Eggers P., Van Lente F., & Levey A. S. Prevalence of chronic kidney disease in the United States. JAMA, 2007, № 298 (17), pp. 2038–2047. doi: 10.1001/jama.298.17.2038

8. Vivante A., Golan E., Tzur D., Leiba A., Tirosh A., Skorecki K., & Calderon-Margalit R. Body mass index in 1.2 million adolescents and risk for end-stage renal disease. Archives of internal medicine, 2012, № 172 (21), pp. 1644–1650. doi: 10.1001/2013.jamainternmed.85

9. Gussaova S. S., Bobkova I. N., Yashkov Yu. I., Stavrovskaya E. V., Bordan N. S., Bekuzarov D. K., Evdoshenko V. V., Fedenko V. V., Malykhina A. I., The effect of surgical correction of body weight on albuminuria and nephrinuria in patients with morbid obesity. Clinical pharmacology and Therapy, 2022, vol. 31, № 1, pp. 62–68. URL: https://clinpharm-journal.ru/articles/2022-1/vliyanie-hirurgicheskoj-korrektsii-massy-tela-na-albuminuriyu-i-nefrinuriyu-u-bolnyh-s-morbidnym-ozhireniem/?ysclid=la9lnms3cd111165565 (in Russ.)

10. Panwar B., Hanks L. J., Tanner R. M., Muntner P., Kramer H., McClellan W. M., Warnock D. G., Judd S. E., & Gutiérrez O. M. Obesity, metabolic health, and the risk of end-stage renal disease. Kidney international, 2015, № 87 (6), pp. 1216–1222. doi: 10.1038/ki.2014.384

11. Ebbert J. O., & Jensen M. D. Fat depots, free fatty acids, and dyslipidemia. Nutrients, 2013, № 5 (2), pp. 498–508. doi: 10.3390/nu5020498

12. Chang Y., Ryu S., Cho J., Pastor-Barriuso R., & Guallar E. Metabolically Healthy Obesity and Development of Chronic Kidney Disease. Annals of internal medicine, 2016, № 165 (10), pp. 744–745. doi: 10.7326/L16-0405

13. Jung C. H., Lee M. J., Kang Y. M., Hwang J. Y., Kim E. H., Park J. Y., Kim H. K., & Lee W. J. The risk of chronic kidney disease in a metabolically healthy obese population. Kidney international, 2015, № 88 (4), pp. 843–850. doi: 10.1038/ki.2015.183

14. Warnock D. G., McClellan W., McClure L. A., Newsome B., Campbell R. C., Audhya P., Cushman M., Howard V. J., & Howard G. Prevalence of chronic kidney disease and anemia among participants in the Reasons for Geographic and Racial Differences in Stroke (REGARDS) Cohort Study: baseline results. Kidney international, 2005, № 68 (4), pp. 1427–1431. doi: 10.1111/j.1523-1755.2005.00553.x

15. Stenvinkel P., Zoccali C., & Ikizler T. A. Obesity in CKD-what should nephrologists know? Journal of the American Society of Nephrology: JASN, 2013, № 24 (11), pp. 1727–1736. doi: 10.1681/ASN.2013040330

16. Navaneethan S. D., Yehnert H., Moustarah F., Schreiber M. J., Schauer P. R. & Beddhu S. Weight loss interventions in chronic kidney disease: a systematic review and meta-analysis. Clinical journal of the American Society of Nephrology: CJASN, 2009, № 4 (10), pp. 1565–1574. doi: 10.2215/CJN.02250409

17. Imam T. H., Fischer H., Jing B., Burchette R., Henry S., De Rose S. F. & Coleman K. J. Estimated GFR Before and After Bariatric Surgery in CKD. American journal of kidney diseases: the official journal of the National Kidney Foundation, 2017, № 69 (3), pp. 380–388. doi: 10.1053/j.ajkd.2016.09.020

18. Yemini, R., Nesher, E., Carmeli, I., Winkler, J., Rahamimov, R., Mor, E., & Keidar, A. Bariatric Surgery Is Efficacious and Improves Access to Transplantation for Morbidly Obese Renal Transplant Candidates. Obesity surgery, 2019, 29 (8), 2373–2380. doi: 10.1007/s11695-019-03925-1

19. Hoogeveen E. K., Aalten J., Rothman K. J., et al. Effect of obesity on the outcome of kidney transplantation: a 20-year follow-up. Transplantation, 2011, № 91 (8), pp. 869–74. doi: 10.1097/TP.0b013e3182100f3a.

20. Richards J., Gunson B., Johnson J., et al. Weight gain and obesity after liver transplantation. Transpl Int, 2005, № 18 (4), pp. 461–466. doi: 10.1111/j.1432-2277.2004.00067.x.

21. Mucha K., Foroncewicz B., Ryter M., et al. Weight gain in renal transplant recipients in a Polish single centre. Ann Transplant., 2015, № 20, рр. 16–20. doi: 10.12659/AOT.892754.

22. Brethauer, S. A., Aminian, A., Romero-Talamás, H., Batayyah, E., Mackey, J., Kennedy, L., Kashyap, S. R., Kirwan, J. P., Rogula, T., Kroh, M., Chand, B., & Schauer, P. R. Can diabetes be surgically cured? Long-term metabolic effects of bariatric surgery in obese patients with type 2 diabetes mellitus. Annals of surgery, 2013, № 258 (4), pp. 628–637. doi: 10.1097/SLA.0b013e3182a5034b

23. Gussaova S. S., Bobkova I. N., Yashkov Yu. I., et al. Changes in metabolic parameters and glomerular filtration rate in patientswith morbid obesity after bariatric surgery. Therapeutic Archive, 2020, № 92 (6), pp. 53–59. doi: 10.26442/00403660.2020.06.000674 (in Russ.)

24. Marterre W. F., Hariharan S., First M. R., & Alexander J. W. Gastric bypass in morbidly obese kidney transplant recipients. Clinical transplantation, 1996, № 10 (5), pp. 414–419.

25. Thomas I. A., Gaynor J. J., Joseph T., De La Cruz-Munoz N., Sageshima J., Kupin W., Chen L. J., Ciancio G., Burke G. W., Mattiazzi A. D., Roth D. & Guerra G. Roux-en-Y gastric bypass is an effective bridge to kidney transplantation: Results from a single center. Clinical transplantation, 2018, № 32 (5), e13232. doi: 10.1111/ctr.13232

26. Gill J. S., Hendren E., Dong J., Johnston, O., & Gill, J. Differential association of body mass index with access to kidney transplantation in men and women. Clinical journal of the American Society of Nephrology: CJASN, 2014, № 9 (5), pp. 951–959. doi: 10.2215/CJN.08310813

27. Angrisani L., Cutolo P. P., Formisano G., Nosso G., & Vitolo G. Laparoscopic adjustable gastric banding versus Roux-en-Y gastric bypass: 10-year results of a prospective, randomized trial. Surgery for obesity and related diseases: official journal of the American Society for Bariatric Surgery, 2013, № 9 (3), pp. 405–413. doi: 10.1016/j.soard.2012.11.011

28. Suter M., Calmes J. M., Paroz A. & Giusti V. A 10-year experience with laparoscopic gastric banding for morbid obesity: high long-term complication and failure rates. Obesity surgery, 2006, № 16 (7), pp. 829–835. doi: 10.1381/096089206777822359

29. Kassam A. F., Mirza A., Kim Y., Hanseman D., Woodle E. S., Quillin R. C., Johnson B. L., Govil A., Cardi M., Schauer D. P., Smith E. P., & Diwan T. S. Long-term outcomes in patients with obesity and renal disease after sleeve gastrectomy. American journal of transplantation: official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2020, № 20 (2), pp. 422–429. doi: 10.1111/ajt.15650

30. Bobkova I. N., Gussaova S. S., Stavrovskaya E. V., Struve A. V. Nephrological aspects of surgical weight correction in morbid obesity. Therapeutic Archive, 2018, № 90 (6), рр. 98–104 doi: doi: 10.26442/terarkh201890698-104 (in Russ.)