<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">mossj</journal-id><journal-title-group><journal-title xml:lang="ru">Московский хирургический журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Moscow Surgical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2072-3180</issn><publisher><publisher-name>ООО «ПРОФИЛЬ – 2С»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.17238/2072-3180-2025-1-56-63</article-id><article-id custom-type="elpub" pub-id-type="custom">mossj-908</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>АБДОМИНАЛЬНАЯ ХИРУРГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ABDOMINAL SURGERY</subject></subj-group></article-categories><title-group><article-title>Ретроспективный анализ с использованием машинного обучения и поиска значимых КТ-признаков для оптимизации предоперационной подготовки пациентов с большими и гигантскими послеоперационными вентральными грыжами</article-title><trans-title-group xml:lang="en"><trans-title>Retrospective ct-analysis using machine learning and feature selection for optimizing preoperative preparation of patients with large and giant postoperative ventral hernias</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5439-9262</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Протасов</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Protasov</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Протасов Андрей Витальевич, доктор медицинских наук, профессор, заведующий кафедрой оперативной хирургии и кли­нической анатомии имени И.Д. Кирпатовского</p><p>117198, ул. Миклухо-Маклая, д. 8, г. Москва</p></bio><bio xml:lang="en"><p>Protasov Andrey Vitalievich, Doctor of Medical Sciences, Profes­sor, Head of the Department of Operative Surgery and Clinical Anato­my named after I.D. Kirpatovsky</p><p>117198, Miklukho-Maklaya St. 8, Moscow</p></bio><email xlink:type="simple">andrei.protasov@bk.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0260-1478</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Канахина</surname><given-names>Л. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Kanakhina</surname><given-names>L. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Канахина Лия Бекетаевна, аспирант кафедры оперативной хирургии и клинической анатомии имени И.Д. Кирпатовского</p><p>117198, ул. Миклухо-Маклая, д. 8, г. Москва</p></bio><bio xml:lang="en"><p>Kanakhina Liya Beketaevna, Postgraduate student of the Depart­ment of Operative Surgery and Clinical Anatomy named after I.D. Kirpatovsky</p><p>117198, Miklukho-Maklaya St. 8, Moscow</p></bio><email xlink:type="simple">glb.1994@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2677-6272</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мазурова</surname><given-names>О. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Mazurova</surname><given-names>O. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мазурова Ольга Игоревна, кандидат медицинских наук, ас­систент кафедры оперативной хирургии и клинической анатомии имени И.Д. Кирпатовского</p><p>117198, ул. Миклухо-Маклая, д. 8, г. Москва</p></bio><bio xml:lang="en"><p>Mazurova Olga Igorevna, Candidate of Medical Sciences, As­sistant Professor of the Department of Operative Surgery and Clini­cal Anatomy named after I.D. Kirpatovsky</p><p>117198, Miklukho-Maklaya St. 8, Moscow</p></bio><email xlink:type="simple">mazurova_oi@kb85.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0007-9981-2840</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чорбаджи</surname><given-names>А. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Chorbadzhi</surname><given-names>A. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Чорбаджи Андрей Павлович, ординатор кафедры оператив­ной хирургии и клинической анатомии имени И.Д. Кирпатовского</p><p>117198, ул. Миклухо-Маклая, д. 8, г. Москва</p></bio><bio xml:lang="en"><p>Chorbadzhi Andrey Pavlovich, Resident of the Department of Operative Surgery and Clinical Anatomy named after I.D. Kirpatovsky</p><p>117198, Miklukho-Maklaya St. 8, Moscow</p></bio><email xlink:type="simple">956ach357@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГАОУ ВО "Российский университет дружбы народов имени Патриса Лумумбы"</institution><country>Россия</country></aff><aff xml:lang="en"><institution>FSAEI HE "Patrice Lumumba Peoples' Friendship University of Russia"</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>18</day><month>03</month><year>2025</year></pub-date><volume>0</volume><issue>1</issue><fpage>56</fpage><lpage>63</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Протасов А.В., Канахина Л.Б., Мазурова О.И., Чорбаджи А.П., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Протасов А.В., Канахина Л.Б., Мазурова О.И., Чорбаджи А.П.</copyright-holder><copyright-holder xml:lang="en">Protasov A.V., Kanakhina L.B., Mazurova O.I., Chorbadzhi A.P.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.mossj.ru/jour/article/view/908">https://www.mossj.ru/jour/article/view/908</self-uri><abstract><sec><title>Введение</title><p>Введение. Цель: разработать методику выявления ключевых признаков КТ-абдоменометрии, помогающих хирургу принимать решения о предоперационной подготовке пациентов с большими послеоперационными вентральными грыжами (W3) с использованием алгоритмов машинного обучения.</p></sec><sec><title>Материал и методы</title><p>Материал и методы. В ретроспективное исследование включено 90 пациентов (2020-2024 гг.), разделенных на три группы: без послеоперационных вентральных грыж (ПОВГ) (N=30), с W2 ПОВГ (N=30) и с W3 ПОВГ (N=30). Анализировались параметры мышц передней брюшной стенки, окружность брюшной полости, ширина грыжевых ворот, Defect ratio (%) и индекс разделения компонентов. Применялись ANOVA, критерий Краскела-Уоллиса, t-критерий Стьюдента, U-критерий Манна-Уитни, Random Forest, логистическая регрессия и кластеризация (K-Means, DBSCAN). Результаты. Логистическая регрессия показала точность 86 % (AUC-ROC = 0,95). Значимыми предикторами ботулинотерапии оказались Defect ratio (%), индекс разделения компонентов и площадь мышц (справа). Кластеризация методом K-Means позволила выделить группы пациентов, одна из которых на 83 % состояла из пациентов, получавших ботулинотерапию, что подтверждает объективную дифференциацию по клиническим показаниям. Оптимальный порог вероятности предсказания ботулинотерапии составил 0,6, что снижает количество ложных отрицательных предсказаний.</p></sec><sec><title>Выводы</title><p>Выводы. Использование машинного обучения позволило объективизировать процесс принятия решений и персонализировать предоперационное планирование, снижая субъективный фактор и повышая точность прогнозирования ботулинотерапии.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Introduction</title><p>Introduction. Purpose: this study aimed to develop a machine learning-based approach for identifying key CT abdominometry features to assist in the preoperative planning of patients with large and giant postoperative ventral hernias.</p><p>Materials and methods of research. A retrospective analysis was conducted on 90 patients examined between 2020 and 2024. Patients were divided into three groups: those without postoperative ventral hernias (n=30), patients with W2 hernias (n=30), and patients with large or giant hernias who underwent preoperative botulinum therapy (n=30). CT scans of the abdomen, retroperitoneum, and pelvis were performed, and parameters such as anterior abdominal wall muscle characteristics, abdominal circumference, hernia gate width, defect ratio, and component separation index were measured. Statistical analyses included ANOVA, the Kruskal-Wallis test, Student’s t-test, and the Mann-Whitney U test. Feature selection was performed using a random forest algorithm, logistic regression was utilized for predicting the need for botulinum therapy, and clustering methods (K-Means, DBSCAN) were applied to identify distinct patient subgroups.</p></sec><sec><title>Treatment results</title><p>Treatment results. Logistic regression achieved an accuracy of 86 % (AUC-ROC = 0,95). 'The defect ratio, component separation index, and right muscle area were identified as significant predictors for botulinum therapy. K-Means clustering delineated a subgroup in which 83 % of patients underwent botulinum therapy, underscoring the objective differentiation based on CT features. An optimal predictive threshold of 0.6 was established to minimize false negatives.</p></sec><sec><title>Conclusion</title><p>Conclusion. The application of machine learning techniques facilitates objective and personalized preoperative planning, thereby enhancing surgical decision-making in the management of postoperative ventral hernias.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>инженерия признаков</kwd><kwd>машинное обучение</kwd><kwd>вентральные грыжи</kwd><kwd>КТ-абдоминометрия</kwd><kwd>герниология</kwd></kwd-group><kwd-group xml:lang="en"><kwd>feature engineering</kwd><kwd>Machine learning</kwd><kwd>ventral hernias</kwd><kwd>CT-abdominometry</kwd><kwd>herniology</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Le Huu Nho R., Mege D., Ouaïssi M., Sielezneff I., Sastre B. Incidence and prevention of ventral incisional hernia. J. Visc. Surg., 2012, № 149, e3– e14. https://doi.org/10.1016/j.jviscsurg.2012.05.004</mixed-citation><mixed-citation xml:lang="en">Le Huu Nho R., Mege D., Ouaïssi M., Sielezneff I., Sastre B. Incidence and prevention of ventral incisional hernia. Journal of Vascular Surgery, 2012, vol. 149, pp. e3–e14. https://doi.org/10.1016/j.jviscsurg.2012.05.004</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Fink C., Baumann P., Wente M. N., Knebel P., Bruckner T., Ulrich A., Werner J., Büchler M. W., Diener M. K. Incisional hernia rate 3 years after midline laparotomy. Br. J. Surg., 2014, № 101, pp. 51–54. https://doi.org/10.1002/bjs.9364</mixed-citation><mixed-citation xml:lang="en">Fink C., Baumann P., Wente M.N., Knebel P., Bruckner T., Ulrich A., Werner J., Büchler M.W., Diener M.K. Incisional hernia rate 3 years after midline laparotomy. British Journal of Surgery, 2014, № 101, pp. 51–54. https://doi.org/10.1002/bjs.9364</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Министерство здравоохранения Российской федерации. Общероссийская общественная организация «Российское общество хирургов», Всероссийская общественная организация «Общество герниологов». Клинические рекомендации «Послеоперационная вентральная грыжа». URL: https://cr.minzdrav.gov.ru/preview-cr/685_2 (дата обращения: 23–02–2025).</mixed-citation><mixed-citation xml:lang="en">Ministry of Health of the Russian Federation. All-Russian public organization “Russian Society of Surgeons”, All-Russian public organization “Society of Herniologists”. Clinical recommendations «Posleoperacionnaja ventralnaja gryzha» [Postoperative ventral hernia]. (In Russ.). Available at: https://cr.minzdrav.gov.ru/preview-cr/685_2. (accessed: 23–02–2025)</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Сулайманова Н., Рахмонов Ш., Махмудов Ф., Рахимов А. Мониторинг внутрибрюшного давления и профилактика синдрома абдоминальной компрессии при герниопластике больших и гигантских срединных грыж. Вестник врача, 2014. № 1, С. 171–174. URL: https://inlibrary.uz/index.php/doctors_herald/article/view/4568 (дата обращения: 23–02–2025).</mixed-citation><mixed-citation xml:lang="en">Sulaymanova N., Rakhmonov Sh., Makhmudov F., Rakhimov A. Monitoring of intra-abdominal pressure and prevention of abdominal compression syndrome in hernioplasty of large and giant median hernias. Vestnik vracha, 2014, № 1, pp. 171–174. (In Russ.) Available at: https://inlibrary.uz/index.php/doctors_herald/article/view/4568 (accessed: 23–02–2025)</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Самарцев В.А., Гаврилов В.А., Пушкарев Б.С. Синдром интраабдоминальной гипертензии: современное состояние проблемы. Хирургическая практика, 2020. № 2. С. 35–42. https://doi.org/10.38181/2223–2427–2020–2–35–42</mixed-citation><mixed-citation xml:lang="en">Samartsev V.A., Gavrilov V.A., Pushkarev B.S. Intraabdominal hypertension syndrome: the current state of the problem. Khirurgicheskaya praktika, 2020, № 2, pp. 35–42. (In Russ.). https://doi.org/10.38181/2223–2427–2020–2–35–42</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Vasiliadis K., Knaebel H. P., Djakovic N., Nyarangi–Dix J., Schmidt J., Büchler M. Challenging surgical management of a giant inguinoscrotal hernia: Report of a case. Surg. Today., 2010, № 40, pp. 684–687. https://doi.org/10.1007/s00595–009–4125–3</mixed-citation><mixed-citation xml:lang="en">Vasiliadis K., Knaebel H.P., Djakovic N., Nyarangi–Dix J., Schmidt J., Büchler M. Challenging surgical management of a giant inguinoscrotal hernia: Report of a case. Surgery Today, 2010, № 40, pp. 684–687. https://doi.org/10.1007/s00595–009–4125–3</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">El–Dessouki N. I. Preperitoneal mesh hernioplasty in giant inguinoscrotal hernias: A new technique with dual benefit in repair and abdominal rooming. Hernia., 2001, № 5, pp. 177–181. https://doi.org/10.1007/s10029–001–0030–4</mixed-citation><mixed-citation xml:lang="en">El–Dessouki N.I. Preperitoneal mesh hernioplasty in giant inguinoscrotal hernias: A new technique with dual benefit in repair and abdominal rooming. Hernia, 2001, vol. 5, pp. 177–181. https://doi.org/10.1007/s10029–001–0030–4</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Топчиев А.М., Протасов А.В., Федосеев А.В., Топчиев М.А., Паршин Д.С., Самсонов А.В. Возможности интраоперационного вытяжения мышечно–фасциальных структур передней брюшной стенки как этап подготовки их к пластике при послеоперационных грыжах W3. Совр. пробл. науки и образования., 2022, № 5, С. 140–140. https://doi.org/10.17513/spno.32137</mixed-citation><mixed-citation xml:lang="en">Topchiev A.M., Protasov A.V., Fedoseev A.V., Topchiev M.A., Parshin D.S., Samsonov A.V. Possibilities of intraoperative stretching of the musculofascial structures of the anterior abdominal wall as a stage of their preparation for plastic surgery in postoperative hernias W3. Sovremennye problem nauki i obrazovanija, 2022, № 5, pp. 140–140. (In Russ.). https://doi.org/10.17513/spno.32137</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Crist D. W., Gadacz T. R. Complications of laparoscopic surgery. Surg. Clin. N. Am., 1993, № 73, pp. 265–289. https://doi.org/10.1016/S0039–6109(16)45981–5</mixed-citation><mixed-citation xml:lang="en">Crist D.W., Gadacz T.R. Complications of laparoscopic surgery. Surgical clinics of North America, 1993, № 73, pp. 265–289. https://doi.org/10.1016/S0039–6109(16)45981–5</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Huerta S., et al. Botulinum Toxin A as an Adjunct for the Repair of Giant Inguinal Hernias: Case Reports and a Review of the Literature. J. Clin. Med., 2024, № 13(7), pр. 1879. https://doi.org/10.3390/jcm13071879</mixed-citation><mixed-citation xml:lang="en">Huerta S. et al. Botulinum Toxin A as an Adjunct for the Repair of Giant Inguinal Hernias: Case Reports and a Review of the Literature. Journal of Clinical Medicine, 2024, vol. 13, № 7, pp. 1879. https://doi.org/10.3390/jcm13071879</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
