mossjМосковский хирургический журналMoscow Surgical Journal2072-3180ООО «ПРОФИЛЬ – 2С»10.17238/2072-3180-2024-4-263-270mossj-873Research ArticleЛИТЕРАТУРНЫЕ ОБЗОРЫLITERARY REVIEWSПрименение смешанной реальности в онкоурологической практике (обзор литературы)Application of Mixed Reality in oncourological practice (literature review)https://orcid.org/0000-0001-5836-0066ИзмайловА. А.IzmailovA. A.

Измайлов Альберт Аделевич – врач-онколог онкоурологического отделения, 

аспирант, 143423, Московская область, Красногорский район, п\о Степановское, поселок Истра, дом 27

Izmailov Albert Adelevich – oncologist of oncourology deparment,

PhD researcher, 27 Istra settlement, Stepanovskoye settlement, Krasnogorsky district,Moscow region

albertizmailov96@gmail.comhttps://orcid.org/0000-0003-3246-7337СеменякинИ. В.SemenyakinI. V.

Семенякин Игорь Владимирович – д.м.н., медицинский директор,

123056, Москва

Semeniakin Igor Vladimirovich – Doctor of Medical Sciences, Medical Director,

123056, Moscow

dr.semeniakin@gmail.comhttps://orcid.org/0000-0002-6255-0193ГаджиевН. К.GadzhievN. K.

Гаджиев Нариман Казиханович – д.м.н., заместитель директора по медицинской части (урология),

190103, Санкт-Петербург, наб. р. Фонтанки, 154

Gadzhiev Nariman Kazihanovich – Doctor of Medical Sciences, deputy Director of the Medical Part (Urology),

embankment, 190103, St.Petersburg, 154, Fontanka river

nariman.gadjiev@gmail.comhttps://orcid.org/0000-0002-1594-4704ФоминВ. С.FominV. S.

Фомин Владимир Сергеевич – к.м.н., доцент, хирург,

127644, Москва, ул. Лобненская, д. 10

Fomin Vladimir Sergeevich – MD, PhD, Associate Professor, surgeon,

st. Lobnenskaya, 10, 127644, Moscow

wlfomin83@gmail.comГБУЗ МГОБ (Московская городская онкологическая больница) № 62 ДЗ; МНИОИ им. П.А. Герцена – филиал ФГБУ «НМИЦ радиологии» Минздрава РоссииРоссияMoscow City Oncology Hospital № 62; P.A. Hertzen Moscow Oncology Research Institute – branch of the National Medical Research Radiological Center, Ministry of Health of RussiaRussian FederationАО «Группа компаний «Медси»РоссияАО GK «Medsi group» JSCRussian FederationКлиника высоких медицинских технологий им. Н.И. Пирогова, ФГБОУ ВО "Санкт-Петербургский государственный университет"РоссияSaint Petersburg State University HospitalRussian FederationГБУЗ ГКБ им. В.В. Вересаева Департамента здравоохранения города МосквыРоссияVeresaev City Clinical HospitalRussian Federation20242412202404263270Copyright © Измайлов А.А., Семенякин И.В., Гаджиев Н.К., Фомин В.С., 20242024Измайлов А.А., Семенякин И.В., Гаджиев Н.К., Фомин В.С.Izmailov A.A., Semenyakin I.V., Gadzhiev N.K., Fomin V.S.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.mossj.ru/jour/article/view/873

За последние 5 лет ежегодно растет число научных публикаций, посвященных применению технологии смешанной реальности (СР) в хирургической практике. Одной из составляющих СР является технология виртуальной реальности (ВР), которая используется в медицинской практике в целях обучения с конца 20 века. СР пришла на смену виртуальной реальности (ВР) и расширила возможности применения технологии для хирургических вмешательств, в том числе с возможностью применения непосредственно во время операции. В онкоурологической практике СР активно применяется при резекциях почки, забрюшинных и спасительных лимфаденэктомиях. Нами представлен обзор литературы по возможностям и результатам применения технологии.

In the last 5 years, the number of scientific publications about mixed reality (MR) in surgery is significantly increased.

One of the component of MR is virtual reality (VR) technology, which has been used in medicine for training purposes since the end of the 20th century. MR replaced virtual reality (VR) and expanded the possibilities of using technology for surgical interventions, including the possibility of using it directly during surgery. In oncourological practice, MR is actively using for kidney resections, retroperitoneal and salvage lymphadenectomies.

The main way of using MR technologies in oncourology are partial nephrectomy, retroperitoneal and salvage lymphadenectomy.

We introduce literature review of using possibilities and results.

виртуальная реальностьсмешанная реальностьрак почкирезекция почкирак предстательной железыспасительная лимфаденэктомияинтраоперационная навигациязабрюшинная лимфаденэктомияvirtual realitymixed realityrenal cell carcinomapartial nephrectomyprostate cancersalvage lymphadenectomyintraoperative navigationretroperitoneal lymphadenectomyReferencesAzuma R.T. A Survey of Augmented Reality. Presence: Teleoperators & Virtual Environments, 1997, Aug; № 6(4), рр. 355–385. https://doi.org/10.1162/pres.1997.6.4.355Azuma R.T. A Survey of Augmented Reality. Presence: Teleoperators & Virtual Environments, 1997, Aug; № 6(4), рр. 355–385. https://doi.org/10.1162/pres.1997.6.4.355Slater M., Sanchez-Vives M.V. Enhancing Our Lives with Immersive Virtual Reality. Front. Robot. AI., 2016, Dec 19; № 3, рр. 74. https://doi.org/10.3389/frobt.2016.00074Slater M., Sanchez-Vives M.V. Enhancing Our Lives with Immersive Virtual Reality. Front. Robot. AI., 2016, Dec 19; № 3, рр. 74. https://doi.org/10.3389/frobt.2016.00074Asadi Z., Asadi M., Kazemipour N., Léger É., Kersten-Oertel M. A decade of progress: bringing mixed reality image-guided surgery systems in the operating room. Comput Assist Surg (Abingdon), 2024, Dec; № 29(1), рр. 2355897. https://doi.org/10.1080/24699322.2024.2355897Asadi Z., Asadi M., Kazemipour N., Léger É., Kersten-Oertel M. A decade of progress: bringing mixed reality image-guided surgery systems in the operating room. Comput Assist Surg (Abingdon), 2024, Dec; № 29(1), рр. 2355897. https://doi.org/10.1080/24699322.2024.2355897Satava R.M. Emerging medical applications of virtual reality: a surgeon’s perspective. Artif Intell Med., 1994, Aug; № 6(4), рр. 281–288. https://doi.org/10.1016/0933-3657(94)90033-7. PMID: 7812423Satava R.M. Emerging medical applications of virtual reality: a surgeon’s perspective. Artif Intell Med., 1994, Aug; № 6(4), рр. 281–288. https://doi.org/10.1016/0933-3657(94)90033-7. PMID: 7812423Figert P.L., Park A.E., Witzke D.B., Schwartz R.W. Transfer of training in acquiring laparoscopic skills. J Am Coll Surg., 2001, Nov; № 193(5), рр. 533–537. https://doi.org/10.1016/s1072-7515(01)01069-9Figert P.L., Park A.E., Witzke D.B., Schwartz R.W. Transfer of training in acquiring laparoscopic skills. J Am Coll Surg., 2001, Nov; № 193(5), рр. 533–537. https://doi.org/10.1016/s1072-7515(01)01069-9Gallagher A.G., Satava R.M. Virtual reality as a metric for the assessment of laparoscopic psychomotor skills. Learning curves and reliability measures. Surg Endosc., 2002, № 16(12), рр. 1746e52.Gallagher A.G., Satava R.M. Virtual reality as a metric for the assessment of laparoscopic psychomotor skills. Learning curves and reliability measures. Surg Endosc., 2002, № 16(12), рр. 1746e52.Ahlberg G., Enochsson L., Gallagher A.G., Hedman L., Hogman C., McClusky D.A.3rd, Ramel S., Smith C.D., Arvidsson D. Proficiency-based virtual reality training significantly reduces the error rate for residents during their first 10 laparoscopic cholecystectomies. Am J Surg., 2007, Jun; № 193(6), рр. 797–804. https://doi.org/10.1016/j.amjsurg.2006.06.050Ahlberg G., Enochsson L., Gallagher A.G., Hedman L., Hogman C., McClusky D.A.3rd, Ramel S., Smith C.D., Arvidsson D. Proficiency-based virtual reality training significantly reduces the error rate for residents during their first 10 laparoscopic cholecystectomies. Am J Surg., 2007, Jun; № 193(6), рр. 797–804. https://doi.org/10.1016/j.amjsurg.2006.06.050Mazzone E., Puliatti S., Amato M., Bunting B., Rocco B., Montorsi F., Mottrie A., Gallagher A.G. A Systematic Review and Meta-analysis on the Impact of Proficiency-based Progression Simulation Training on Performance Outcomes. Ann Surg., 2021, Aug 1; № 274(2), рр. 281–289. https://doi.org/10.1097/SLA.0000000000004650Mazzone E., Puliatti S., Amato M., Bunting B., Rocco B., Montorsi F., Mottrie A., Gallagher A.G. A Systematic Review and Meta-analysis on the Impact of Proficiency-based Progression Simulation Training on Performance Outcomes. Ann Surg., 2021, Aug 1; № 274(2), рр. 281–289. https://doi.org/10.1097/SLA.0000000000004650Andreatta P.B., Woodrum D.T., Birkmeyer J.D., Yellamanchilli R.K., Doherty G.M., Gauger P.G., Minter R.M. Laparoscopic skills are improved with LapMentor training: results of a randomized, double-blinded study. Ann Surg., 2006, Jun; № 243(6), рр. 854–860. https://doi.org/10.1097/01.sla.0000219641.79092.e5Andreatta P.B., Woodrum D.T., Birkmeyer J.D., Yellamanchilli R.K., Doherty G.M., Gauger P.G., Minter R.M. Laparoscopic skills are improved with LapMentor training: results of a randomized, double-blinded study. Ann Surg., 2006, Jun; № 243(6), рр. 854–860. https://doi.org/10.1097/01.sla.0000219641.79092.e5Sherman V., Feldman L.S., Stanbridge D., Kazmi R., Fried G.M. Assessing the learning curve for the acquisition of laparoscopic skills on a virtual reality simulator. Surg Endosc., 2005, May; № 19(5), рр. 678–682. https://doi.org/10.1007/s00464-004-8943-5Sherman V., Feldman L.S., Stanbridge D., Kazmi R., Fried G.M. Assessing the learning curve for the acquisition of laparoscopic skills on a virtual reality simulator. Surg Endosc., 2005, May; № 19(5), рр. 678–682. https://doi.org/10.1007/s00464-004-8943-5Sparn M.B., Teixeira H., Chatziisaak D., Schmied B., Hahnloser D., Bischofberger S. Virtual reality simulation training in laparoscopic surgery - does it really matter, what simulator to use? Results of a crosssectional study. BMC Med Educ., 2024, May 28; № 24(1), рр. 589. https://doi.org/10.1186/s12909-024-05574-0Sparn M.B., Teixeira H., Chatziisaak D., Schmied B., Hahnloser D., Bischofberger S. Virtual reality simulation training in laparoscopic surgery - does it really matter, what simulator to use? Results of a crosssectional study. BMC Med Educ., 2024, May 28; № 24(1), рр. 589. https://doi.org/10.1186/s12909-024-05574-0Под ред. Каприна А.Д., Старинского В.В., Шахзадово А.О. Злокачественные новообразования в России в 2022 году (заболеваемость и смертность) М. : МНИОИ им. П.А. Герцена − филиал ФГБУ «НМИЦ радиологии» Минздрава России, 2023. 275 с.Ed. Kaprina A.D., Starinsky V.V., Shakhzadova A.O. Malignant neoplasms in Russia in 2022 (morbidity and mortality) M. : P.A. Herzen Moscow State Medical Research Institute − branch of the Federal State Budgetary Institution «NMIC of Radiology» of the Ministry of Health of Russia, 2023, 275 p.Sung H., Ferlay J., Siegel R.L. et al. Global cancer statistics 2020:gLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin., 2021, № 71(3), рр. 209–249.Sung H., Ferlay J., Siegel R.L. et al. Global cancer statistics 2020:gLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin., 2021, № 71(3), рр. 209–249.Van Poppel H., Da Pozzo L., Albrecht W., Matveev V., Bono A., Borkowski A., Marechal J.M., Klotz L., Skinner E., Keane T., Claessens I., Sylvester R. European Organization for Research and Treatment of Cancer (EORTC); National Cancer Institute of Canada Clinical Trials Group (NCIC CTG); Southwest Oncology Group (SWOG); Eastern Cooperative Oncology Group (ECOG). A prospective randomized EORTC intergroup phase 3 study comparing the complications of elective nephron-sparing surgery and radical nephrectomy for low-stage renal cell carcinoma. Eur Urol., 2007, Jun; № 51(6), рр. 1606–1615. https://doi.org/10.1016/j.eururo.2006.11.013Van Poppel H., Da Pozzo L., Albrecht W., Matveev V., Bono A., Borkowski A., Marechal J.M., Klotz L., Skinner E., Keane T., Claessens I., Sylvester R. European Organization for Research and Treatment of Cancer (EORTC); National Cancer Institute of Canada Clinical Trials Group (NCIC CTG); Southwest Oncology Group (SWOG); Eastern Cooperative Oncology Group (ECOG). A prospective randomized EORTC intergroup phase 3 study comparing the complications of elective nephron-sparing surgery and radical nephrectomy for low-stage renal cell carcinoma. Eur Urol., 2007, Jun; № 51(6), рр. 1606–1615. https://doi.org/10.1016/j.eururo.2006.11.013Janssen M.W.W., Linxweiler J., Terwey S., Rugge S., Ohlmann C.H., Becker F., Thomas C., Neisius A., Thüroff J.W., Siemer S., Stöckle M., Roos F.C. Survival outcomes in patients with large (≥7cm) clear cell renal cell carcinomas treated with nephron-sparing surgery versus radical nephrectomy: Results of a multicenter cohort with long-term follow-up. PLoS One, 2018, May 3; № 13(5), рр. e0196427. https://doi.org/10.1371/journal.pone.0196427Janssen M.W.W., Linxweiler J., Terwey S., Rugge S., Ohlmann C.H., Becker F., Thomas C., Neisius A., Thüroff J.W., Siemer S., Stöckle M., Roos F.C. Survival outcomes in patients with large (≥7cm) clear cell renal cell carcinomas treated with nephron-sparing surgery versus radical nephrectomy: Results of a multicenter cohort with long-term follow-up. PLoS One, 2018, May 3; № 13(5), рр. e0196427. https://doi.org/10.1371/journal.pone.0196427Клинические рекомендации МЗ РФ. Рак паренхимы почки. Режим доступа: https://old.oncology-association.ru/clinical-guidelinesupdate. Ссылка активна на 15.12.2022.Clinical recommendations of the Ministry of Health of the Russian Federation. Cancer of the parenchyma of the kidney. Available at: https://old.oncology-association.ru/clinicalguidelines-update. Accessed: 15.12.2022 (in Russian).Каприн А.Д., Костин А.А., Степанов С.О., Воробьев Н.В., Беспалов П.Д., Димитров В.О. Анализ возможностей применений интраоперационного ультразвукового исследования при хирургическом лечении опухолей почек. Research’n Practical Medicine Journal, 2019, № 6(1), рр. 50–59. https://doi.org/10.17709/2409-2231-2019-6-1-5Kaprin A.D., Kostin A.A., Stepanov S.O., Vorobyov N.V., Bespalov P.D., Dimitrov V.O. Analysis of the possibilities of using intraoperative ultrasound in the surgical treatment of kidney tumors. Research’n Practical Medicine Journal, 2019, № 6(1), рр. 50–59. https://doi.org/10.17709/2409-2231-2019-6-1-5 (in Russian)Chopra S., Bove A.M., Gill I.S. Robotic Partial Nephrectomy: Advanced Techniques and Use of Intraoperative Imaging. In: Su, LM. (eds) Atlas of Robotic Urologic Surgery. Springer, Cham., 2017. https://doi.org/10.1007/978-3-319-45060-5_7Chopra S., Bove A.M., Gill I.S. Robotic Partial Nephrectomy: Advanced Techniques and Use of Intraoperative Imaging. In: Su, LM. (eds) Atlas of Robotic Urologic Surgery. Springer, Cham., 2017. https://doi.org/10.1007/978-3-319-45060-5_7Wunderlich H., Reichelt O., Schubert R., Zermann D.H., Schubert J. Preoperative simulation of partial nephrectomy with three-dimensional computed tomography. BJU Int., 2000, Nov; № 86(7), рр. 777–781. https://doi.org/10.1046/j.1464-410x.2000.00898.xWunderlich H., Reichelt O., Schubert R., Zermann D.H., Schubert J. Preoperative simulation of partial nephrectomy with three-dimensional computed tomography. BJU Int., 2000, Nov; № 86(7), рр. 777–781. https://doi.org/10.1046/j.1464-410x.2000.00898.xSilberstein J.L., Maddox M.M., Dorsey P., Feibus A., Thomas R., Lee B.R. Physical models of renal malignancies using standard cross-sectional imaging and 3-dimensional printers: a pilot study. Urology, 2014, Aug; № 84(2), рр. 268–272. https://doi.org/10.1016/j.urology.2014.03.042Silberstein J.L., Maddox M.M., Dorsey P., Feibus A., Thomas R., Lee B.R. Physical models of renal malignancies using standard cross-sectional imaging and 3-dimensional printers: a pilot study. Urology, 2014, Aug; № 84(2), рр. 268–272. https://doi.org/10.1016/j.urology.2014.03.042Komai Y., Sugimoto M., Gotohda N., Matsubara N., Kobayashi T., Sakai Y., Shiga Y., Saito N. Patient-specific 3-dimensional Printed Kidney Designed for «4D» Surgical Navigation: A Novel Aid to Facilitate Minimally Invasive Off-clamp Partial Nephrectomy in Complex Tumor Cases. Urology, 2016, May; № 91, рр. 226–233. https://doi.org/10.1016/j.urology.2015.11.060Komai Y., Sugimoto M., Gotohda N., Matsubara N., Kobayashi T., Sakai Y., Shiga Y., Saito N. Patient-specific 3-dimensional Printed Kidney Designed for «4D» Surgical Navigation: A Novel Aid to Facilitate Minimally Invasive Off-clamp Partial Nephrectomy in Complex Tumor Cases. Urology, 2016, May; № 91, рр. 226–233. https://doi.org/10.1016/j.urology.2015.11.060Porpiglia F., Checcucci E., Amparore D., Piramide F., Volpi G., Granato S., Verri P., Manfredi M., Bellin A., Piazzolla P., Autorino R., Morra I., Fiori C., Mottrie A. Three-dimensional Augmented Reality Robot-assisted Partial Nephrectomy in Case of Complex Tumours (PADUA ≥10): A New Intraoperative Tool Overcoming the Ultrasound Guidance. Eur Urol., 2020, Aug; № 78(2), рр. 229–238. https://doi.org/10.1016/j.eururo.2019.11.024Porpiglia F., Checcucci E., Amparore D., Piramide F., Volpi G., Granato S., Verri P., Manfredi M., Bellin A., Piazzolla P., Autorino R., Morra I., Fiori C., Mottrie A. Three-dimensional Augmented Reality Robot-assisted Partial Nephrectomy in Case of Complex Tumours (PADUA ≥10): A New Intraoperative Tool Overcoming the Ultrasound Guidance. Eur Urol., 2020, Aug; № 78(2), рр. 229–238. https://doi.org/10.1016/j.eururo.2019.11.024Семенякин И.В., Гаджиев Н.К., Габдуллин А.Ф., Погосян Р.Р., Джалилов И.Б., Кузьмина И.Н., Моршнев А.В. Применение смешанной реальности при лапароскопической резекции почки. Московский хирургический журнал, 2021. № 4. C. 47–57. https://doi.org/10.17238/2072-3180-2021-4-47-57Semenyakin I.V., Gadzhiev N.K., Gabdullin A.F., Poghosyan R.R., Jalilov I.B., Kuzmina I.N., Morshnev A.V. The use of mixed reality in laparoscopic kidney resection. Moscow Surgical Journal, 2021, № 4, рр. 47–57. https://doi.org/10.17238/2072-3180-2021-4-47-57 (in Russian)Gadzhiev N, Semeniakin I, Morshnev A., Alcaraz A., Gauhar V., Okhunov Z. Role and Utility of Mixed Reality Technology in Laparoscopic Partial Nephrectomy: Outcomes of a Prospective RCT Using an Indigenously Developed Software. Adv Urol., 2022, May 16; № 2022, рр. 8992051. https://doi.org/10.1155/2022/8992051Gadzhiev N, Semeniakin I, Morshnev A., Alcaraz A., Gauhar V., Okhunov Z. Role and Utility of Mixed Reality Technology in Laparoscopic Partial Nephrectomy: Outcomes of a Prospective RCT Using an Indigenously Developed Software. Adv Urol., 2022, May 16; № 2022, рр. 8992051. https://doi.org/10.1155/2022/8992051Gandaglia G., Ploussard G., Valerio M., Mattei A., Fiori C., Fossati N., Stabile A., Beauval J.B., Malavaud B., Roumiguié M., Robesti D., Dell’Oglio P., Moschini M., Zamboni S., Rakauskas A., De Cobelli F., Porpiglia F., Montorsi F., Briganti A. A Novel Nomogram to Identify Candidates for Extended Pelvic Lymph Node Dissection Among Patients with Clinically Localized Prostate Cancer Diagnosed with Magnetic Resonance Imaging-targeted and Systematic Biopsies. European Urology, Volume 75, Issue 3, 2019, рр. 506–514. https://doi.org/10.1016/j.eururo.2018.10.012Gandaglia G., Ploussard G., Valerio M., Mattei A., Fiori C., Fossati N., Stabile A., Beauval J.B., Malavaud B., Roumiguié M., Robesti D., Dell’Oglio P., Moschini M., Zamboni S., Rakauskas A., De Cobelli F., Porpiglia F., Montorsi F., Briganti A. A Novel Nomogram to Identify Candidates for Extended Pelvic Lymph Node Dissection Among Patients with Clinically Localized Prostate Cancer Diagnosed with Magnetic Resonance Imaging-targeted and Systematic Biopsies. European Urology, Volume 75, Issue 3, 2019, рр. 506–514. https://doi.org/10.1016/j.eururo.2018.10.012Keegan K.A., Cookson M.S. Complications of pelvic lymph node dissection for prostate cancer. Curr Urol Rep., 2011, Jun; № 12(3), рр. 203– 208. https://doi.org/10.1007/s11934-011-0179-zKeegan K.A., Cookson M.S. Complications of pelvic lymph node dissection for prostate cancer. Curr Urol Rep., 2011, Jun; № 12(3), рр. 203– 208. https://doi.org/10.1007/s11934-011-0179-zMorris M.J., Rowe S.P., Gorin M.A., Saperstein L., Pouliot F., Josephson D., Wong J.Y.C., Pantel A.R., Cho S.Y., Gage K.L., Piert M., Iagaru A., Pollard J.H., Wong V., Jensen J., Lin T., Stambler N., Carroll P.R., Siegel B.A. CONDOR Study Group. Diagnostic Performance of 18F-DCFPyLPET/CT in Men with Biochemically Recurrent Prostate Cancer: Results from the CONDOR Phase III, Multicenter Study. Clin Cancer Res., 2021, Jul 1; № 27(13), рр. 3674–3682. https://doi.org/10.1158/1078-0432.CCR20-4573Morris M.J., Rowe S.P., Gorin M.A., Saperstein L., Pouliot F., Josephson D., Wong J.Y.C., Pantel A.R., Cho S.Y., Gage K.L., Piert M., Iagaru A., Pollard J.H., Wong V., Jensen J., Lin T., Stambler N., Carroll P.R., Siegel B.A. CONDOR Study Group. Diagnostic Performance of 18F-DCFPyLPET/CT in Men with Biochemically Recurrent Prostate Cancer: Results from the CONDOR Phase III, Multicenter Study. Clin Cancer Res., 2021, Jul 1; № 27(13), рр. 3674–3682. https://doi.org/10.1158/1078-0432.CCR20-4573Fendler W.P., Calais J., Eiber M., Flavell R.R., Mishoe A., Feng F.Y., Nguyen H.G., Reiter R.E., Rettig M.B., Okamoto S., Emmett L., Zacho H.D., Ilhan H., Wetter A., Rischpler C., Schoder H., Burger I.A., Gartmann J., Smith R., Small E.J., Slavik R., Carroll P.R., Herrmann K., Czernin J., Hope T.A. Assessment of 68Ga-PSMA-11 PET Accuracy in Localizing Recurrent Prostate Cancer: A Prospective Single-Arm Clinical Trial. JAMA Oncol., 2019, Jun 1; № 5(6), рр. 856–863. https://doi.org/10.1001/jamaoncol.2019.0096Fendler W.P., Calais J., Eiber M., Flavell R.R., Mishoe A., Feng F.Y., Nguyen H.G., Reiter R.E., Rettig M.B., Okamoto S., Emmett L., Zacho H.D., Ilhan H., Wetter A., Rischpler C., Schoder H., Burger I.A., Gartmann J., Smith R., Small E.J., Slavik R., Carroll P.R., Herrmann K., Czernin J., Hope T.A. Assessment of 68Ga-PSMA-11 PET Accuracy in Localizing Recurrent Prostate Cancer: A Prospective Single-Arm Clinical Trial. JAMA Oncol., 2019, Jun 1; № 5(6), рр. 856–863. https://doi.org/10.1001/jamaoncol.2019.0096Ploussard G., Gandaglia G., Borgmann H., de Visschere P., Heidegger I., Kretschmer A., Mathieu R., Surcel C., Tilki D., Tsaur I., Valerio M., van den Bergh R., Ost P., Briganti A. EAU-YAU Prostate Cancer Working Group. Salvage Lymph Node Dissection for Nodal Recurrent Prostate Cancer: A Systematic Review. Eur Urol., 2019, Oct; № 76(4), рр. 493–504. https://doi.org/10.1016/j.eururo.2018.10.041Ploussard G., Gandaglia G., Borgmann H., de Visschere P., Heidegger I., Kretschmer A., Mathieu R., Surcel C., Tilki D., Tsaur I., Valerio M., van den Bergh R., Ost P., Briganti A. EAU-YAU Prostate Cancer Working Group. Salvage Lymph Node Dissection for Nodal Recurrent Prostate Cancer: A Systematic Review. Eur Urol., 2019, Oct; № 76(4), рр. 493–504. https://doi.org/10.1016/j.eururo.2018.10.041Fossati N., Suardi N., Gandaglia G., Bravi C.A., Soligo M., Karnes R.J., Shariat S., Battaglia A., Everaerts W., Joniau S., Van Poppel H., Rajarubendra N., Gill I.S., Larcher A., Mottrie A., Schmautz M., Heidenreich A., Kalz A., Osmonov D., Juenemann K.P., Herlemann A., Gratzke C., Stief C., Montorsi F., Briganti A. Identifying the Optimal Candidate for Salvage Lymph Node Dissection for Nodal Recurrence of Prostate Cancer: Results from a Large, Multi-institutional Analysis. Eur Urol., 2019, Jan; № 75(1), рр. 176–183. https://doi.org/10.1016/j.eururo.2018.09.009Fossati N., Suardi N., Gandaglia G., Bravi C.A., Soligo M., Karnes R.J., Shariat S., Battaglia A., Everaerts W., Joniau S., Van Poppel H., Rajarubendra N., Gill I.S., Larcher A., Mottrie A., Schmautz M., Heidenreich A., Kalz A., Osmonov D., Juenemann K.P., Herlemann A., Gratzke C., Stief C., Montorsi F., Briganti A. Identifying the Optimal Candidate for Salvage Lymph Node Dissection for Nodal Recurrence of Prostate Cancer: Results from a Large, Multi-institutional Analysis. Eur Urol., 2019, Jan; № 75(1), рр. 176–183. https://doi.org/10.1016/j.eururo.2018.09.009Широкорад В.И., Измайлов А.А., Лупашко Д.Г. Спасительная лимфаденэктомия при олигометастатическом лимфогенном прогрессировании рака предстательной железы: анализ литературы и собственный опыт. Онкоурология, 2024. № 20(1). С. 52–59. https://doi.org/10.17650/1726-9776-2024-20-1-52-59Shirokorad V.I., Izmailov A.A., Lupashko D.G. Life-saving lymphadenectomy in oligometastatic lymphogenic progression of prostate cancer: literature analysis and own experience. Oncourology, 2024, № 20(1), рр. 52–59. https://doi.org/10.17650/1726-9776-2024-20-1-52-59 (in Russian)Krishnan G., Berg N.Svd., Nishio N., Juniper G., Pei J., Zhou Q., Lu G., Lee Y.J., Ramos K., Iagaru A.H., Baik F.M., Colevas A.D., Martin B.A., Rosenthal E.L. Metastatic and sentinel lymph node mapping using intravenously delivered Panitumumab-IRDye800CW. Theranostics, 2021, № 11(15), рр. 7188–7198. https://doi.org/10.7150/thno.55389Krishnan G., Berg N.Svd., Nishio N., Juniper G., Pei J., Zhou Q., Lu G., Lee Y.J., Ramos K., Iagaru A.H., Baik F.M., Colevas A.D., Martin B.A., Rosenthal E.L. Metastatic and sentinel lymph node mapping using intravenously delivered Panitumumab-IRDye800CW. Theranostics, 2021, № 11(15), рр. 7188–7198. https://doi.org/10.7150/thno.55389Nishio N., van den Berg N.S., van Keulen S. et al. Optical molecular imaging can differentiate metastatic from benign lymph nodes in head and neck cancer. Nat Commun, 2019, № 10(1), рр. 5044.Nishio N., van den Berg N.S., van Keulen S. et al. Optical molecular imaging can differentiate metastatic from benign lymph nodes in head and neck cancer. Nat Commun, 2019, № 10(1), рр. 5044.Vonk J., de Wit J.G., Voskuil F.J. et al. Epidermal Growth Factor Receptor-Targeted Fluorescence Molecular Imaging for Postoperative Lymph Node Assessment in Patients with Oral Cancer. J Nucl Med., 2022, № 63(5), рр. 672–678.Vonk J., de Wit J.G., Voskuil F.J. et al. Epidermal Growth Factor Receptor-Targeted Fluorescence Molecular Imaging for Postoperative Lymph Node Assessment in Patients with Oral Cancer. J Nucl Med., 2022, № 63(5), рр. 672-678.

The authors declare that there are no conflicts of interest present.