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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">mossj</journal-id><journal-title-group><journal-title xml:lang="ru">Московский хирургический журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Moscow Surgical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2072-3180</issn><publisher><publisher-name>ООО «ПРОФИЛЬ – 2С»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.17238/2072-3180-2024-2-52-61</article-id><article-id custom-type="elpub" pub-id-type="custom">mossj-777</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОНКОЛОГИЯ</subject></subj-group></article-categories><title-group><article-title>Персонализированное 3D-моделирование артериального русла для выполнения сосудисто-ориентированной расширенной лимфодиссекции при колоректальном раке</article-title><trans-title-group xml:lang="en"><trans-title>Personalized 3D-modeling of the arterial bloodstream for performing vascular-oriented extended lymph node dissection for colorectal cancer</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0283-2217</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ефетов</surname><given-names>С. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Efetov</surname><given-names>S. К.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ефетов Сергей Константинович – кандидат медицинских наук, доцент</p><p>119048, Москва, ул. Доватора д. 15</p></bio><bio xml:lang="en"><p>Efetov Sergey Konstantinovich – Candidate of Medical Sciences, Associate Professor</p><p>119048, 15 Dovator str., Moscow</p></bio><email xlink:type="simple">efetov@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0009-5809-8948</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рычкова</surname><given-names>А. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Rychkova</surname><given-names>А. К.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Рычкова Арина Кирилловна – студент 6 курса</p><p>119435, Москва, ул. Россолимо д. 11 ст. 2</p></bio><bio xml:lang="en"><p>Rychkova Arina Kirillovna – a 6th year student</p><p>119435, 11 Rossolimo str., p.2, Moscow</p></bio><email xlink:type="simple">ockun.riba@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8647-7605</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хлусов</surname><given-names>Д. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Khlusov</surname><given-names>D. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Хлусов Денис Игоревич – врач-онколог-хирург Университетской клинической больницы № 4</p><p>119048, Москва, ул. Доватора д. 15</p></bio><bio xml:lang="en"><p>Khlusov Denis Igorevich – Oncologist-surgeon of the University clinical hospital No 4</p><p>119048, 15 Dovator str., Moscow</p></bio><email xlink:type="simple">denis.khlusov@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0015-7094</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Секачева</surname><given-names>М. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Sekacheva</surname><given-names>М. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Секачева Марина Игоревна – доктор медицинских наук, профессор, директор</p><p>119435, Москва, ул. Большая Пироговская, д. 6, стр. 1</p></bio><bio xml:lang="en"><p>Sekacheva Marina Igorevna – Doctor of Medical Sciences, Professor, Director</p><p>119435, 6 Bolshaya Pirogovskaya str, p. 2, Moscow</p></bio><email xlink:type="simple">sekacheva_m_i@staff.sechenov.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0617-6392</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хоробрых</surname><given-names>Т. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Khorobrykh</surname><given-names>Т. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Хоробрых Татьяна Витальевна – доктор медицинских наук, профессор РАН, директор клиники</p><p>119048, Москва, ул. Доватора д. 15</p></bio><bio xml:lang="en"><p>Khorobrykh Tatiana Vitalievna – Doctor of Medical Sciences, Professor of the Russian Academy of Sciences</p><p>119048, 15 Dovator str., Moscow</p><p> </p></bio><email xlink:type="simple">khorobrykh_t_v@staff.sechenov.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Кафедра факультетской хирургии № 2 им. Г.И. Лукомского ИКМ им. Н.В. Склифосовского ФГАОУ ВО Первый Московский государственный медицинский университет имени И.М. Сеченова (Сеченовский Университет) Минздрава РФ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Department of Faculty Surgery № 2 named after G. I. Lukomsky, N.V. Sklifosovsky ICM, I.M. Sechenov First Moscow State Medical University (Sechenov University) The Ministry of Health of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Институт клинической медицины им. Н.В. Склифосовского ФГАОУ ВО Первый Московский государственный медицинский университет имени И.М. Сеченова (Сеченовский Университет) Минздрава РФ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>N.V. Sklifosovsky Institute of Clinical Medicine of the Sechenov First Moscow State Medical University (Sechenov University) Ministry of Health of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Институт персонализированной онкологии, кафедра онкологии, радиотерапии и реконструктивной хирургии ИКМ им. Н.В. Склифосовского ФГАОУ ВО Первый Московский государственный медицинский университет имени И.М. Сеченова (Сеченовский Университет) Минздрава РФ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Institute of Personalized Oncology, Department of Oncology, Radiotherapy and Reconstructive Surgery of the N.V. Sklifosovsky ICM of the I.M. Sechenov First Moscow State Medical University (Sechenov University) Ministry of Health of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>19</day><month>05</month><year>2024</year></pub-date><volume>0</volume><issue>2</issue><fpage>52</fpage><lpage>61</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Ефетов С.К., Рычкова А.К., Хлусов Д.И., Секачева М.И., Хоробрых Т.В., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Ефетов С.К., Рычкова А.К., Хлусов Д.И., Секачева М.И., Хоробрых Т.В.</copyright-holder><copyright-holder xml:lang="en">Efetov S.К., Rychkova А.К., Khlusov D.I., Sekacheva М.I., Khorobrykh Т.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.mossj.ru/jour/article/view/777">https://www.mossj.ru/jour/article/view/777</self-uri><abstract><sec><title>Введение</title><p>Введение. В хирургическом лечении колоректального рака лимфодиссекция имеет ключевое значение.</p></sec><sec><title>Цель исследования</title><p>Цель исследования. Определить преимущества персонализированного 3D-моделирования мезентериальных сосудов для выполнения сосудисто-ориентированной расширенной лимфодиссекции при колоректальном раке.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. Пациентам с верифицированной аденокарциномой ободочной или прямой кишки проводилось построение 3D-моделей сосудистого русла брыжейки. На предоперационном этапе оценивались типы строения верхней брыжеечной артерии (ВБА) и нижней брыжеечной артерии (НБА). Было проведено сравнение времени операции и количества удаленных лимфоузлов между группами с применением 3D-КТ и без применения 3D-КТ.</p></sec><sec><title>Результаты</title><p>Результаты. В исследование включены 146 пациентов с колоректальным раком. Строение НБА по типу Е1 было выявлено у 28 (41,1 %) пациентов, Е2 у 3 (4,4 %), Е3 у 6 (8,8 %), К-тип у 11 (16,2 %), а Н-тип у 20 (29,5%). Для ВБА наличие правой ободочной артерии зафиксировано в 5 (22,7 %) случаях. Средняя ободочная артерия отсутствовала у одного пациента (5,5 %). Средняя продолжительность операции значительно не различалась в группах с 3D-КТ и без 3D-КТ. Количество удаленных лимфоузлов было больше в группах, где применялось 3D-КТ (26±13 и 19±7, p value = 0.00139 для рака левой половины, и 41±26 и 17±5, p value &lt; 0.00001 для рака правой половины).</p></sec><sec><title>Заключение</title><p>Заключение. Рутинное изучение 3D-реконструкций позволяет дооперационно определить строение сосудов в зоне лимфодиссекции, что улучшает интраоперационную навигацию</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Introduction</title><p>Introduction. In the surgical treatment of colorectal cancer, lymph node dissection is very important.</p></sec><sec><title>Study Objective</title><p>Study Objective. To determine the advantages of personalized 3D-modeling of mesenteric vessels for performing vascular-oriented extended lymph node dissection in the treatment of colorectal cancer.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. The patients with verified adenocarcinoma of colon or rectum underwent the construction of 3D-models of mesenteric vascular bloodstream. At the preoperative stage, the types of the superior mesenteric artery (SMA) and the inferior mesenteric artery (IMA) were evaluated. The operative time and the number of harvested lymph nodes were compared between the groups with and without 3D-CT.</p></sec><sec><title>Results</title><p>Results. A total of 146 patients with colorectal cancer were included in the study. E1-type of the IMA was found in 28 (41,1 %) patients, E2 in 3 (4,4 %), E3 in 6 (8,8 %), K-type in 11 (16,2 %), and H-type in 20 (29,5 %). For SMA, the presence of the right colic artery was detected in 5 (22,7 %) cases. The middle colic artery was absent in one patient (5,5 %). The average duration of surgery did not differ significantly between the groups with and without 3D-CT. The number of harvested lymph nodes was higher in the groups with 3D-CT (26±13 and 19±7, p value = 0.00139 for left-sided cancer, and 41±26 and 17±5, p value &lt;0.00001 for right-sided cancer).</p></sec><sec><title>Conclusion</title><p>Conclusion. Routine examination of 3D-reconstructions allows preoperative determination of vessel’s structure in the lymph node dissection zone, which improves intraoperative navigation.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>3D-моделирование</kwd><kwd>колоректальный рак</kwd><kwd>лимфодиссекция</kwd><kwd>нижняя брыжеечная артерия</kwd><kwd>верхняя брыжеечная артерия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>3D-modeling</kwd><kwd>colorectal cancer</kwd><kwd>lymph node dissection</kwd><kwd>inferior mesenteric artery</kwd><kwd>superior mesenteric artery</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Царьков П.В., Ефетов С.К., Зубайраева А.А., Пузаков К.Б., Оганян Н.В. Роль хирурга в определении анатомии нижней брыжеечной артерии по данным компьютерной томографии при лечении колоректального рака. Хирургия. Журнал им. Н.И. Пирогова, 2022 № (9). 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