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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">mossj</journal-id><journal-title-group><journal-title xml:lang="ru">Московский хирургический журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Moscow Surgical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2072-3180</issn><publisher><publisher-name>ООО «ПРОФИЛЬ – 2С»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.17238/2072-3180-2023-2-123-97</article-id><article-id custom-type="elpub" pub-id-type="custom">mossj-687</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ЛИТЕРАТУРНЫЕ ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>LITERARY REVIEWS</subject></subj-group></article-categories><title-group><article-title>Современные взгляды на патогенез и лечение щелочного рефлюкс-гастрита развившегося после резекции желудка. (обзор литературы)</article-title><trans-title-group xml:lang="en"><trans-title>Modern views on the pathogenesis and treatment of alkaline reflux gastritis developing after gastric resection. (literature review)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7383-196X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Исаев</surname><given-names>Г. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Isaev</surname><given-names>G. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Гидаят Билал Исаев оглы, д. м. н., проф., главный научный сотрудник</p><p>отделение абдоминальной хирургии</p><p>AZ1122</p><p>Аббас Мирза Шарифзаде, 196</p><p>Баку</p></bio><bio xml:lang="en"><p>Guidayat Bilal Isaev oglu, Doctor of Medical Sciences, Prof., Chief Researcher</p><p>Department of Abdominal Surgery</p><p>AZ1122</p><p>Bakikhanov str., 23</p><p>Baku</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4221-0471</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Алиев</surname><given-names>Ю. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Aliyev</surname><given-names>Yu. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Юсиф Дамед Алиев оглы, д. м. н., профессор</p><p>кафедра хирургии </p><p>AZ1022</p><p>ул. Бакиханова, 23</p><p>Баку</p></bio><bio xml:lang="en"><p>Yusif Damed Aliyev oglu, MD, Professor</p><p>Department of Surgery</p><p>AZ1022</p><p>Bakikhanov str., 23</p><p>Baku</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3792-6192</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Джафарли</surname><given-names>Р. Э.</given-names></name><name name-style="western" xml:lang="en"><surname>Jafarli</surname><given-names>R. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Расим Эльхан Джафарли оглы, д. м. н., доцент</p><p>кафедра хирургии</p><p>AZ1122</p><p>AZ1022</p><p>ул. Бакиханова, 23</p><p>Баку</p></bio><bio xml:lang="en"><p>Rasim Elkhan Jafarli oglu, MD, Associate Professor</p><p>Department of Surgery</p><p>AZ1122</p><p>AZ1022</p><p>Bakikhanov str., 23</p><p>Baku</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0001-8971-1209</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Аббасзаде</surname><given-names>Т. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Abbaszade</surname><given-names>T. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Турал Надир Абасзаде оглы, к. м. н., научный сотрудник</p><p>отделение абдоминальной хирургии НЦХ</p><p>AZ1122</p><p>Аббас Мирза Шарифзаде, 196</p><p>Баку</p></bio><bio xml:lang="en"><p>Tural Nadir Abaszade oglu, Candidate of Medical Sciences, Researcher</p><p>Department of Abdominal Surgery</p><p>AZ1122</p><p>Bakikhanov str., 23</p><p>Baku</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0007-5144-4321</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Эфендиев</surname><given-names>З. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Efеndiyev</surname><given-names>Z. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Захид Самир Эфендиев оглы, ординатор</p><p>отделение обдиминальной хирургии</p><p>AZ1022</p><p>Kızılcaşar, 23 Nisan Cd. № 20, 06830 Gölbaşı</p><p>Баку</p><p>Турция</p><p>Анкара</p></bio><bio xml:lang="en"><p>Zahid Samir Eftndiev oglu, </p><p>AZ1022</p><p>23 Nisan Cd. № 20, 06830 Gölbaşı</p><p>Baku</p><p>Turkey</p><p>Ankara</p></bio><xref ref-type="aff" rid="aff-4"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Научный Центр Хирургии им. академика М. А. Топчибашева</institution><country>Азербайджан</country></aff><aff xml:lang="en"><institution>Scientific Center of Surgery named after Academician M. A. Topchibashev</institution><country>Azerbaijan</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Азербайджанский Медицинский Университет</institution><country>Азербайджан</country></aff><aff xml:lang="en"><institution>Azerbaijan Medical University</institution><country>Azerbaijan</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Научный Центр Хирургии им. академика М. А. Топчибашева; Азербайджанский Медицинский Университет</institution><country>Азербайджан</country></aff><aff xml:lang="en"><institution>Scientific Center of Surgery named after Academician M. A. Topchibashev; Azerbaijan Medical University</institution><country>Azerbaijan</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>Азербайджанский Медицинский Университет; LOSEF-Losante Childiren and ADULT Hospital</institution><country>Азербайджан</country></aff><aff xml:lang="en"><institution>Azerbaijan Medical University; LOSEF-Losante Childiren and ADULT Hospital</institution><country>Azerbaijan</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>17</day><month>07</month><year>2023</year></pub-date><volume>0</volume><issue>2</issue><fpage>123</fpage><lpage>132</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Исаев Г.Б., Алиев Ю.Д., Джафарли Р.Э., Аббасзаде Т.Н., Эфендиев З.С., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Исаев Г.Б., Алиев Ю.Д., Джафарли Р.Э., Аббасзаде Т.Н., Эфендиев З.С.</copyright-holder><copyright-holder xml:lang="en">Isaev G.B., Aliyev Y.D., Jafarli R.E., Abbaszade T.N., Efеndiyev Z.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.mossj.ru/jour/article/view/687">https://www.mossj.ru/jour/article/view/687</self-uri><abstract><sec><title>   Введение</title><p>   Введение. Среди больных с осложненными язвами в 25–50 % случаях развивается хроническая дуоденальная непроходимость (ХДН). С другой стороны, сама резекция желудка является причиной нарушения нормальной функции дуоденального сфинктера. Сведения о частоте дуоденогастрального рефлюкса (ДГР) при язвенной болезни и после резекций желудка весьма противоречивы.</p><p>   Цель исследования – представить современные взгляды на патогенез и лечение щелочного рефлюкс-гастрита, развившегося после резекции желудка.</p></sec><sec><title>   Материал и методы</title><p>   Материал и методы. Поиск литературы проводили в электронных базах: Параграф Медицина, Web of Knowledge (ThomsonReuters), Scopus, Pubmed Medline, The Сocrane Library, Springer Link, Ebscohost S cience Direct. Промежуток поиска составил с 2003 по 2020 гг. (за исключением 5 источников). Анализированы 250 источников. В обзор включены 40 статьей по указанной теме, которые были доступны в виде полного текста.</p></sec><sec><title>   Полученные результаты</title><p>   Полученные результаты. До настоящего времени число постгастрорезекционных осложнений, включая ДГР, существенно не снижается. Одним из методов профилактики ДГР является выявление в дооперационном периоде ХДП. Единственный вариант гастроэнтероанастомоза, который может предупредить ДГР, – это анастомоз на Ру-петле.</p></sec><sec><title>   Заключение</title><p>   Заключение. Эти больные должны быть оперированы в клиниках, где хирурги безукоризненно владеют разнообразными видами операций на пищеводе, желудка и ДПК. Данные литературы свидетельствуют о том, что у большинства пациентов с чрезмерным энтеро-гастральным рефлюксом преобразование в длинную петлю Roux-en-Y приводит к устойчивому симптоматическому эффекту в течение не менее 3 лет.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>   Introduction</title><p>   Introduction. Among patients with complicated ulcers, in 25–50% of cases there are chronic duodenal obstruction (CDO), on the other hand, the resection of the stomach itself is the cause of the disruption of the normal function of the duodenal sphincter. Data on the frequency of duodenogastric reflux in peptic ulcer and after gastric resections are very contradictory.</p><p>   Purpose – to present modern views on the pathogenesis and treatment of alkaline reflux gastritis that develops after gastric resection.</p></sec><sec><title>   Material and methods</title><p>   Material and methods. Literature search was carried out in the following electronic databases: Paragraph Medicine, Web of Knowledge (ThomsonReuters), Scopus, Pubmed Medline, The Сocrane Library, Springer Link, Ebscohost Science Direct. The search period was from 2003 to 2020 (with the exception of 5 sources:). More than 250 sources have been analyzed. The review includes 40 articles on the specified topic, which were available in full text and analyzed by critical evaluation.</p></sec><sec><title>   Results</title><p>   Results. Summarizing the literature review, we can say that there are no significant reductions in the number of post-gastroresection complications, including duodeno-gastric reflux (DGR). One of the methods for the prevention of DGR is the detection of CDO in the preoperative period. The only variant of gastroenteroanastomosis that can prevent enterogastric bile reflux is a Roux-loop anastomosis.</p></sec><sec><title>   Conclusions</title><p>   Conclusions. These patients should be operated on in clinics where surgeons are impeccably proficient in various types of operations on the esophagus, stomach and duodenum. Literature data suggest that in the majority of patients with excessive enterogastric reflux, transformation into a long loop of Roux-en-Y leads to a stable symptomatic effect for at least 3 years.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>резекция желудка</kwd><kwd>патогенез и лечение щелочного рефлюкс-гастрита</kwd></kwd-group><kwd-group xml:lang="en"><kwd>gastric resection</kwd><kwd>pathogenesis and treatment of alkaline reflux gastritis</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Ширинская Н. В. Язвенная болезнь желудка и двенадцатиперстной кишки в Российской Федерации. Заболеваемость и смертность. Общественное здоровье и здравоохранения, 2016. С. 105–109.</mixed-citation><mixed-citation xml:lang="en">Shirinskaya N. V. Peptic ulcer of the stomach and duodenum in the Russian Federation. Morbidity and mortality. 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