<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">mossj</journal-id><journal-title-group><journal-title xml:lang="ru">Московский хирургический журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Moscow Surgical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2072-3180</issn><publisher><publisher-name>ООО «ПРОФИЛЬ – 2С»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.17238/2072-3180-2021-4-15-22</article-id><article-id custom-type="elpub" pub-id-type="custom">mossj-508</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>АБДОМИНАЛЬНАЯ ХИРУРГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ABDOMINAL SURGERY</subject></subj-group></article-categories><title-group><article-title>Профилактика острой пострезекционной печеночной недостаточности у больных эхинококковом печени</article-title><trans-title-group xml:lang="en"><trans-title>Prevention of acute post-hepatectomy liver failure in patient with liver echinococcosis</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4230-8033</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шабунин</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Shabunin</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p> член-корр. РАН, д.м.н., профессор, заведующий кафедрой хирургии; главный врач </p><p> Россия, 125284, Москва, 2-й Боткинский проезд, д. 5</p></bio><bio xml:lang="en"><p> Corresponding Member of the Russian Academy of Sciences, Professor, Doctor of Medicine, Head of the surgery department; clinic chief</p><p> Russia, 125284, Moscow, 2-nd Botkinsky pr., 5 </p></bio><email xlink:type="simple">glavbotkin@zdrav.mos.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8441-6561</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бедин</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Bedin</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p> д.м.н., доцент кафедры хирургии; заместитель главного врача по хирургии </p><p>Россия, 125284, Москва, 2-й Боткинский проезд, д. 5</p></bio><bio xml:lang="en"><p>Doctor of Medicine, associate professor surgery department; Chief of Surgical Department </p><p>Russia, 125284, Moscow, 2-nd Botkinsky pr., 5 </p></bio><email xlink:type="simple">bedinvv@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0335-1204</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тавобилов</surname><given-names>М. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Tavobilov</surname><given-names>M. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p> д.м.н., доцент кафедры хирургии РМАНПО, заведующий отделением хирургии печени и поджелудочной железы </p><p>Россия, 125284, Москва, 2-й Боткинский проезд, д. 5</p></bio><bio xml:lang="en"><p> Doctor of Medicine, associate professor surgery department, head of the department of liver and pancreas surgery</p><p>Russia, 125284, Moscow, 2-nd Botkinsky pr., 5 </p></bio><email xlink:type="simple">botkintmm@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5142-1302</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Карпов</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Karpov</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p> к.м.н., врач-хирург отделения гепатопанкреатобилиарной хирургии </p><p>Россия, 125284, Москва, 2-й Боткинский проезд, д. 5</p></bio><bio xml:lang="en"><p> Candidate of Medical Scienses., HPB surgeon, HPB department </p><p>Russia, 125284, Moscow, 2-nd Botkinsky pr., 5 </p></bio><email xlink:type="simple">botkin.karpov@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5366-1281</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лебедев</surname><given-names>С. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Lebedev</surname><given-names>S. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p> к.м.н., доцент кафедры хирургии; заведующий центром амбулаторной онкологической помощи </p><p>Россия, 125284, Москва, 2-й Боткинский проезд, д. 5</p></bio><bio xml:lang="en"><p> Candidate of Medical Scienses., associate professor of Surgery Department; HPB surgeon, head of the department of ambulatory oncology</p><p>Russia, 125284, Moscow, 2-nd Botkinsky pr., 5 </p></bio><email xlink:type="simple">lebedevssd@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5142-1302</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Аладин</surname><given-names>М. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Aladin</surname><given-names>M. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p> ординатор кафедры хирургии</p><p>Россия, 125284, Москва, 2-й Боткинский проезд, д. 5</p></bio><bio xml:lang="en"><p>resident of Surgery Department </p><p>Russia, 125284, Moscow, 2-nd Botkinsky pr., 5 </p></bio><email xlink:type="simple">aladinmark97@gmail.com</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Городская клиническая больница им. С.П. Боткина Департамента здравоохранения города Москвы;&#13;
Российская медицинская академия непрерывного профессионального образования Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Botkin Hospital;&#13;
Russian Medical Academy of Postgraduate Study, Ministry of Health of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Городская клиническая больница им. С.П. Боткина Департамента здравоохранения города Москвы</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Botkin Hospital</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Российская медицинская академия непрерывного профессионального образования Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian Medical Academy of Postgraduate Study, Ministry of Health of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>09</day><month>02</month><year>2022</year></pub-date><volume>0</volume><issue>4</issue><fpage>15</fpage><lpage>22</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Шабунин А.В., Бедин В.В., Тавобилов М.М., Карпов А.А., Лебедев С.С., Аладин М.Н., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Шабунин А.В., Бедин В.В., Тавобилов М.М., Карпов А.А., Лебедев С.С., Аладин М.Н.</copyright-holder><copyright-holder xml:lang="en">Shabunin A.V., Bedin V.V., Tavobilov M.M., Karpov A.A., Lebedev S.S., Aladin M.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.mossj.ru/jour/article/view/508">https://www.mossj.ru/jour/article/view/508</self-uri><abstract><p>Введение. Развитие хирургических технологий в последние годы позволяет транслировать опыт лечения больных злокачественными новообразованиями печени на лечение пациентов с доброкачественным поражением печени.Материалы и методы. В хирургической клинике Боткинской больницы с 2020 года при эхинококкозе печени и необходимости выполнения обширных резекций печени стала применяться методика портоэмболизации для развития викарной гипертрофии остающейся доли печени. Проведен анализ результатов лечения 64 пациентов, перенесших резекционный метод лечения с 2007 по 2020 годы. В основную группу вошли 13 больных, 7 из которых за период с 2018 по 2020 год выполнено 8 процедур портоэмболизации. Вторая группа была представлена 51 пациентом, которые были оперированы без предварительной эмболизации правой ветви воротной вены. В исследовании оценены следующие показатели: длительность хирургического вмешательства, объем кровопотери, послеоперационный койко-день, осложнения по классификации Clavien-Dindo, специфические осложнения по ISGLS, рецидивы в течение первого года после хирургического вмешательства.Результаты. Непосредственные результаты хирургического лечения (количество общехирургических осложнений в послеоперационном периоде и его длительность) у больных после предоперационной эмболизации правой ветви воротной вены были значимо лучше, чем у больных оперированных без учета необходимости профилактики развития острой пострезекционной печеночной недостаточности. Результаты отдаленной выживаемости значимых различий не выявили.Выводы. Таким образом, современные хирургические технологии, позволяющие достигать увеличения объема функционирующей паренхимы печени, позволяют уменьшить количество и тяжесть послеоперационных осложнений и улучшить результаты лечения.</p></abstract><trans-abstract xml:lang="en"><p>Introduction. The development of surgical technologies in recent years makes it possible to translate the experience of treating patients with malignant neoplasms of the liver to the treatment of patients with benign liver damage.Methods. Since 2018, in the surgical clinic of the Botkin Hospital, with liver echinococcosis and the need to perform extensive liver resections, the portoembolization technique has been used to develop vicarious hypertrophy of the remaining lobe of the liver. The analysis of the results of treatment of 64 patients who underwent a resection method of treatment was carried out. The main group included 13 patients who underwent 8 portoembolization procedures. The second group was represented by 51 patients who were operated without preliminary embolization of the right branch of the portal vein. The study evaluated the following indicators: duration of surgery, volume of blood loss, postoperative bed-day, complications according to the Clavien-Dindo classification, specific complications according to ISGLS, relapses during the first year after surgery.Results. The immediate results of surgical treatment (the number of general surgical complications in the postoperative period and its duration) in patients after preoperative embolization of the right branch of the portal vein were significantly better than in patients operated on without taking into account the need to prevent the development of acute post-resection hepatic failure. Long-term survival results did not reveal significant differences.Conclusion. Thus, modern surgical technologies that allow to achieve an increase in the volume of the functioning liver parenchyma can reduce the number and severity of postoperative complications and improve treatment results.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>эхинококкоз печени</kwd><kwd>портоэмболизация</kwd><kwd>резекция печени</kwd></kwd-group><kwd-group xml:lang="en"><kwd>liver echinococcosis</kwd><kwd>portal vein embolization</kwd><kwd>liver resection</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Шабунин А.В., Тавобилов М.М., Карпов А.А. Эхинококкоз печени: эволюция хирургического лечения. Хирургия. Журнал им. Н.И. Пирогова, 2021. № 5. С. 5–103. https://doi.org/10.17116/hirurgia202105195</mixed-citation><mixed-citation xml:lang="en">Shabunin A.V., Tavobilov M. M., Karpov A. A. Echinococcosis of the liver: the evolution of surgical treatment. Surgery. Journal named after N. I. Pirogov, 2021, № 5, pp. 5–103. [In Russ.]. https://doi.org/10.17116/hirurgia202105195</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Konishi T., Takamoto T., Hashimoto T., Makuuchi M. Is portal vein embolization safe and effective for patients with impaired liver function? J Surg Oncol., 2021, Mar № 3, 123, рр. 1742–1749. https://doi.org/10.1002/jso.26447 Epub ahead of print. PMID: 33657243.</mixed-citation><mixed-citation xml:lang="en">Konishi T., Takamoto T., Hashimoto T., Makuuchi M. Is portal vein embolization safe and effective for patients with impaired liver function? J Surg Oncol., 2021, Mar № 3, 123, рр. 1742–1749. https://doi.org/10.1002/jso.26447 Epub ahead of print. PMID: 33657243.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Olthof, P. B., Aldrighetti, L., Alikhanov, R., Cescon, M., Koerkamp, B. G., Jarnagin, W. R., van Gulik, T. M. Portal Vein Embolization is Associated with Reduced Liver Failure and Mortality in High-Risk Resections for Perihilar Cholangiocarcinoma; Perihilar Cholangiocarcinoma Collaboration Group. Ann Surg Oncol., 2020, Dec; № 27(Suppl 3), рр. 968. https://doi.org/10.1245/s10434-020-08353-5</mixed-citation><mixed-citation xml:lang="en">Olthof, P. B., Aldrighetti, L., Alikhanov, R., Cescon, M., Koerkamp, B. G., Jarnagin, W. R., van Gulik, T. M. Portal Vein Embolization is Associated with Reduced Liver Failure and Mortality in High-Risk Resections for Perihilar Cholangiocarcinoma; Perihilar Cholangiocarcinoma Collaboration Group. Ann Surg Oncol., 2020, Dec; № 27(Suppl 3), рр. 968. https://doi.org/10.1245/s10434-020-08353-5</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Kim D., Cornman-Homonoff J., Madoff DC. Preparing for liver surgery with “Alphabet Soup”: PVE, ALPPS, TAE-PVE, LVD and RL. Hepatobiliary Surg Nutr., 2020, Apr; № 9(2), рр. 136–151. https://doi.org/10.21037/hbsn.2019.09.10 PMID: 32355673; PMCID: PMC7188547.</mixed-citation><mixed-citation xml:lang="en">Kim D., Cornman-Homonoff J., Madoff DC. Preparing for liver surgery with “Alphabet Soup”: PVE, ALPPS, TAE-PVE, LVD and RL. Hepatobiliary Surg Nutr., 2020, Apr; № 9(2), рр. 136–151. https://doi.org/10.21037/hbsn.2019.09.10 PMID: 32355673; PMCID: PMC7188547.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Madoff D.C., Odisio B.C., Schadde E., Gaba R.C., Bennink R.J., van Gulik T.M., Guiu B. Improving the Safety of Major Resection for Hepatobiliary Malignancy: Portal Vein Embolization and Recent Innovations in Liver Regeneration Strategies. Curr Oncol Rep., 2020, May 16; № 22(6), рр. 59. https://doi.org/10.1007/s11912-020-00922-x. PMID: 32415401</mixed-citation><mixed-citation xml:lang="en">Madoff D.C., Odisio B.C., Schadde E., Gaba R.C., Bennink R.J., van Gulik T.M., Guiu B. Improving the Safety of Major Resection for Hepatobiliary Malignancy: Portal Vein Embolization and Recent Innovations in Liver Regeneration Strategies. Curr Oncol Rep., 2020, May 16; № 22(6), рр. 59. https://doi.org/10.1007/s11912-020-00922-x. PMID: 32415401</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Chan A., Zhang W.Y., Chok K., Dai J., Ji R., Kwan C., Man N., Poon R., Lo C.M. ALPPS Versus Portal Vein Embolization for Hepatitis-related Hepatocellular Carcinoma: A Changing Paradigm in Modulation of Future Liver Remnant Before Major Hepatectomy. Ann Surg., 2021, May 1; № 273(5), рр. 957–965. https://doi.org/10.1097/SLA.0000000000003433 PMID: 31305284.</mixed-citation><mixed-citation xml:lang="en">Chan A., Zhang W.Y., Chok K., Dai J., Ji R., Kwan C., Man N., Poon R., Lo C.M. ALPPS Versus Portal Vein Embolization for Hepatitis-related Hepatocellular Carcinoma: A Changing Paradigm in Modulation of Future Liver Remnant Before Major Hepatectomy. Ann Surg., 2021, May 1; № 273(5), рр. 957–965. https://doi.org/10.1097/SLA.0000000000003433 PMID: 31305284.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Guiu B., Quenet F., Panaro F., Piron L., Cassinotto C., Herrerro A., Souche F.R., Hermida M., Pierredon-Foulongne M.A., Belgour A., Aho-Glele S., Deshayes E. Liver venous deprivation versus portal vein embolization before major hepatectomy: future liver remnant volumetric and functional changes. Hepatobiliary Surg Nutr., 2020, Oct; № 9(5), рр. 564–576. https://doi.org/10.21037/hbsn.2020.02.06 PMID: 33163507; PMCID: PMC7603937.</mixed-citation><mixed-citation xml:lang="en">Guiu B., Quenet F., Panaro F., Piron L., Cassinotto C., Herrerro A., Souche F.R., Hermida M., Pierredon-Foulongne M.A., Belgour A., AhoGlele S., Deshayes E. Liver venous deprivation versus portal vein embolization before major hepatectomy: future liver remnant volumetric and functional changes. Hepatobiliary Surg Nutr., 2020, Oct; № 9(5), рр. 564–576. https://doi.org/10.21037/hbsn.2020.02.06 PMID: 33163507; PMCID: PMC7603937.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Clavien P. A. Barkun J., De Oliveira M. L., Vauthey J. N., Dindo D., Schulick R. D., Graf R. The Clavien-Dindo classification of surgical complications: five-year experience. Annals of surgery, 2009, Т. 250, № 2, рр. 187–196. https://doi.org/10.1097/SLA.0b013e3181b13ca2</mixed-citation><mixed-citation xml:lang="en">P. A. Barkun J., De Oliveira M. L., Vauthey J. N., Dindo D., Schulick R. D., Graf R. The Clavien-Dindo classification of surgical complications: five-year experience. Annals of surgery, 2009, Т. 250, № 2, рр. 187–196. https://doi.org/10.1097/SLA.0b013e3181b13ca2</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Rahbari N.N. Garden O.J., Padbury R., Brooke-Smith M., Crawford M., Adam R., Koch M., Makuuchi M., Dematteo R.P., Christophi C., Banting S., Usatoff V., Nagino M., Maddern G., Hugh T.J., Vauthey J.N., Greig P., Rees M., Yokoyama Y. Y., Fan S. T., Nimura Y., Figueras J., Capussotti L., Büchler M.W., Weitz J. Posthepatectomy liver failure: a definition and grading by the International Study Group of Liver Surgery (ISGLS). Surgery, 2011, May; № 149(5), рр. 713–724. https://doi.org/10.1016/j.surg.2010.10.001 Epub 2011 Jan 14. PMID: 21236455.</mixed-citation><mixed-citation xml:lang="en">Rahbari N.N. Garden O.J., Padbury R., Brooke-Smith M., Crawford M., Adam R., Koch M., Makuuchi M., Dematteo R.P., Christophi C., Banting S., Usatoff V., Nagino M., Maddern G., Hugh T.J., Vauthey J.N., Greig P., Rees M., Yokoyama Y. Y., Fan S. T., Nimura Y., Figueras J., Capussotti L., Büchler M.W., Weitz J. Posthepatectomy liver failure: a definition and grading by the International Study Group of Liver Surgery (ISGLS). Surgery, 2011, May; № 149(5), рр. 713–724. https://doi.org/10.1016/j.surg.2010.10.001 Epub 2011 Jan 14. PMID: 21236455.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
