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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">mossj</journal-id><journal-title-group><journal-title xml:lang="ru">Московский хирургический журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Moscow Surgical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2072-3180</issn><publisher><publisher-name>ООО «ПРОФИЛЬ – 2С»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.17238/issn2072-3180.2021.2.18-25</article-id><article-id custom-type="elpub" pub-id-type="custom">mossj-473</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>АБДОМИНАЛЬНАЯ ХИРУРГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ABDOMINAL SURGERY</subject></subj-group></article-categories><title-group><article-title>ОСТРЫЙ ХОЛЕЦИСТИТ: КАМО ГРЯДЕШИ? ОПЫТ 13 000 ОПЕРАЦИЙ ОДНОЙ КЛИНИКИ</article-title><trans-title-group xml:lang="en"><trans-title>ACUTE CHOLECYSTITIS: QUO VADIS? EXPERIENCE OF 13,000 OPERATIONS IN ONE CLINIC</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8092-0573</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Луцевич</surname><given-names>О. Э.</given-names></name><name name-style="western" xml:lang="en"><surname>Lutsevich</surname><given-names>O. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Луцевич Олег Эммануилович - доктор медицинских наук, профессор, член-корреспондент РАН, Залуженный врач РФ, Лауреат Премии Правительства РФ, заведующий кафедрой факультетской хирургии, главный хирург ЗАО ЦЭЛТ (Москва)</p><p>127254, Москва, ул. Руставели, 3-7-26</p><p> </p></bio><bio xml:lang="en"><p>Oleg E. Lutsevich - Doсt. of Sсi. (Med.), Professor, Corresponding Member of the Russiаn Асаdemy of Sсienсes, head, chief surgeon of CELT (Russia, Moscow)</p><p>20/1, Delegatskaya str., Moscow, 127473</p></bio><email xlink:type="simple">oleglutsevich@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Кафедра факультетской хирургии №1 ФГБОУ ВО «Московский государственный медико-стоматологический университет им. А.И. Евдокимова»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Department of faculty surgery № 1 Moscow state medical and dental University named after A.I. Evdokimov</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>09</day><month>09</month><year>2021</year></pub-date><volume>0</volume><issue>2</issue><fpage>18</fpage><lpage>25</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Луцевич О.Э., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Луцевич О.Э.</copyright-holder><copyright-holder xml:lang="en">Lutsevich O.E.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.mossj.ru/jour/article/view/473">https://www.mossj.ru/jour/article/view/473</self-uri><abstract><p>Актуальность. Хирургическое лечение острого холецистита (ОХ) остается одной из наиболее актуальных проблем неотложной хирургии. ОХ является самым частым осложнением желчнокаменной болезни, достигая 30% и более в структуре этого заболевания. Несмотря на широкое внедрение современных эндовидеохирургических методик, в лечении ОХ остается много нерешенных проблем.Материал и методы. В работе обобщен опыт лечения более 13 000 больных с ЖКБ, которым была выполнена лапароскопическая холецистэктомия. Острый холецистит был отмечен у 3140 пациентов. Автор придерживается активной хирургической тактики — лапароскопическая операция в первые 2–16 часов от поступления при отсутствии абсолютных противопоказаний к наложению пневмоперитонеума.Результаты. В работе рассмотрены технические особенности лапароскопических операций при различных формах ОХ, обсуждаются причины неудовлетворительных результатов хирургического лечения ОХ, такие как поздняя госпитализация и применение малоэффективной консервативной терапии, отдаляющие сроки выздоровления больных. Обсуждены негативные последствия многоэтапных методов лечения ОХ, определен алгоритм раннего радикального хирургического вмешательства. Характер воспалительных изменений стенки ЖП и тканей перипузырного пространства, а также наличие спаечного процесса в брюшной полости не влияли на принятие решения о сроках проведения операции и выборе метода.</p></abstract><trans-abstract xml:lang="en"><p>Relevance. Surgical treatment of acute cholecystitis (AC) remains one of the most urgent problems of emergency surgery. AC is the most frequent complication of gallstone disease, reaching 30% or more in the structure of this disease. Despite the widespread introduction of modern endoscopic surgical techniques, there are still many unresolved problems in the treatment of AC.Material and methods. This paper summarizes the experience of treating more than 13,000 patients with GBD who underwent laparoscopic cholecystectomy. Acute cholecystitis occurred in 3140 patients. The author adheres to active surgical tactics — laparoscopic surgery in the first 2‒16 hours from admission in the absence of absolute contraindications to the pneumoperitoneum.Results. The paper discusses the technical features of laparoscopic operations in various forms of AC, discusses the reasons for unsatisfactory results of surgical treatment of AC, such as late hospitalization and the use of ineffective conservative therapy, delaying the recovery of patients. The negative consequences of multi-stage AC treatment methods are discussed, and an algorithm for early radical surgical intervention is defined. The nature of inflammatory changes in the GB wall and nearby space tissues, as well as the presence of adhesions in the abdominal cavity, did not affect the decision on the timing of the operation and the choice of method.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>Острый холецистит</kwd><kwd>хирургическая тактика</kwd><kwd>ранняя лапароскопическая холецистэктомия</kwd><kwd>причины неудачи лечения</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Acute cholecystitis</kwd><kwd>surgical tactics</kwd><kwd>early laparoscopic cholecystectomy</kwd><kwd>causes of treatment failure</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Бебуришвили А.Г., Панин С.И., Зюбина Е.Н., Быков А.В. Миниинвазивные вмешательства при остром холецистите: состояние проблемы по данным доказательной медицины. Анналы хирургической гепатологии, 2011. Т. 16. № 2. 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