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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">mossj</journal-id><journal-title-group><journal-title xml:lang="ru">Московский хирургический журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Moscow Surgical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2072-3180</issn><publisher><publisher-name>ООО «ПРОФИЛЬ – 2С»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.17238/issn2072-3180.2021.1.23-33</article-id><article-id custom-type="elpub" pub-id-type="custom">mossj-451</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>АБДОМИНАЛЬНАЯ ХИРУРГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ABDOMINAL SURGERY</subject></subj-group></article-categories><title-group><article-title>КОНЦЕПЦИЯ ROUX-EN-Y В ХИРУРГИИ ЗЛОКАЧЕСТВЕННЫХ НОВООБРАЗОВАНИЙ ГАСТРОПАНКРЕАТОДУОДЕНАЛЬНОЙ ЗОНЫ. ОПЫТ И РЕЗУЛЬТАТЫ</article-title><trans-title-group xml:lang="en"><trans-title>THE ROUX-EN-Y CONCEPT IN THE SURGERY OF MALIGNANT TUMORS OF THE GASTROPANCREATODUODENAL REGION. EXPERIENCE AND RESULTS</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Евсеев</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Evseev</surname><given-names>M. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Евсеев Максим Александрович — проф., д.м.н., научный руководитель по хирургии</p><p>121352, г. Москва, ул. Староволынская, 10 </p></bio><bio xml:lang="en"><p>Evseev Maksim Aleksandrovich — professor, MD, Doctor of Medicine, Scientific supervisor of surgery</p><p>121352, Moscow, Starovolynskaya str., 10 </p></bio><email xlink:type="simple">dr.maxim.evseev@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Клишин</surname><given-names>И. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Кlishin</surname><given-names>I. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Клишин Иван Михайлович — к.м.н., врач-хирург отделения абдоминальной хирургии</p><p>121352, г. Москва, ул. Староволынская, 10 </p></bio><bio xml:lang="en"><p>Кlishin Ivan Mikhailovich — MD, PhD in Medicine, surgeon in the Department of abdominal surgery</p><p>121352, Moscow, Starovolynskaya str., 10 </p></bio><email xlink:type="simple">docklishin@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тимошкин</surname><given-names>С. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Timoshkin</surname><given-names>S. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Тимошкин Сергей Павлович — к.м.н., врач-хирург отделения абдоминальной хирургии</p><p>121352, г. Москва, ул. Староволынская, 10 </p></bio><bio xml:lang="en"><p>Timoshkin Sergey Pavlovich — MD, PhD in Medicine, surgeon in the Department of abdominal surgery</p><p>121352, Moscow, Starovolynskaya str., 10 </p></bio><email xlink:type="simple">timoshkin-sergej@list.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Владыкин</surname><given-names>А. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Vladykin</surname><given-names>A. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Владыкин Алексей Леонидович — к.м.н., заведующий отделением абдоминальной хирургии</p><p>121352, г. Москва, ул. Староволынская, 10 </p></bio><bio xml:lang="en"><p>Vladykin Alexey Leonidovich — MD, PhD in Medicine, Head of the Department of abdominal surgery</p><p>121352, Moscow, Starovolynskaya str., 10 </p></bio><email xlink:type="simple">vladykin@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Головин</surname><given-names>Р. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Golovin</surname><given-names>R. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Головин Роман Анатольевич — к.м.н., врач-хирург отделения абдоминальной хирургии</p><p>121352, г. Москва, ул. Староволынская, 10 </p></bio><bio xml:lang="en"><p>Golovin Roman Anatolyevich — MD, PhD in Medicine, surgeon in the Department of abdominal surgery</p><p>121352, Moscow, Starovolynskaya str., 10 </p></bio><email xlink:type="simple">info@volynka.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Евсеев</surname><given-names>А. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Evseev</surname><given-names>A. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Евсеев Александр Максимович — студент</p><p>119991, г. Москва, Ленинские горы,1 </p></bio><bio xml:lang="en"><p>Evseev Aleksandr Maksimovich — student of the Faculty of Medicine</p><p>119991, Moscow Leninskie Gory, 1 </p></bio><email xlink:type="simple">evseevalexandar0@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ «Клиническая больница №1 (Волынская)» Управления делами Президента Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Clinical Hospital 1 (Volynskaya) of the Presidential administration of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБОУВО «Московский государственный университет имени М.В. Ломоносова», Факультет фундаментальной медицины</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Lomonosov Moscow State University, Faculty of Medicine</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>22</day><month>05</month><year>2021</year></pub-date><volume>0</volume><issue>1</issue><fpage>23</fpage><lpage>33</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Евсеев М.А., Клишин И.М., Тимошкин С.П., Владыкин А.Л., Головин Р.А., Евсеев А.М., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Евсеев М.А., Клишин И.М., Тимошкин С.П., Владыкин А.Л., Головин Р.А., Евсеев А.М.</copyright-holder><copyright-holder xml:lang="en">Evseev M.A., Кlishin I.M., Timoshkin S.P., Vladykin A.L., Golovin R.A., Evseev A.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.mossj.ru/jour/article/view/451">https://www.mossj.ru/jour/article/view/451</self-uri><abstract><p>Введение. В настоящее время реконструкция по Ру является стандартным оперативным приемом, а в ряде случаев — методом выбора, при дистальной резекции желудка и гастрэктомии, при повторных операциях на верхнем отделе пищеварительной трубки и формировании билиодигестивных анастомозов, при различных вариантах резекции поджелудочной железы, в практике метаболической/бариатрической хирургии. Целью настоящего исследования являлась демонстрация возможностей применения реконструкции по Ру в хирургии злокачественных новообразований гастропанкреатодуоденальной зоны.Материалы и методы. Авторами представлен опыт использования принципа Roux-en-Y в онкохирургии гастропанкреатодуоденальной зоны при проведении дистальных резекций желудка, тотальных гастрэктомий и гастропанкреатодуоденальных резекций. Проведен сравнительный анализ непосредственных и отдаленных функциональных результатов 267 оперативных вмешательств с реконструкцией по Ру и 79 операций, выполненных с другими вариантами реконструкции.Результаты. Установлены принципиально лучшая переносимость пациентами реконструкции по Ру по критериям течения ближайшего послеоперационного периода (осложнения — 12,8% vs 44,3%, число релапаротомий — 3,4% vs 20,4%, послеоперационная летальность — 4,5% vs 11,3%), а также лучшие функциональные результаты Roux-en-Y реконструкции в отношении возникновения нарушения эвакуации из желудка, желудочного и пищеводного рефлюксов в ближайшем и отдаленном периоде.Заключение. Опыт и результаты применения концепции Roux-en-Y, продемонстрированные в настоящем исследовании, являются очередным подтверждением уникальных свойств данного варианта реконструкции — патогенетической обоснованности, технической воспроизводимости, минимального числа послеоперационных осложнений и прогнозируемости функциональных результатов, в совокупности определяющих востребованность методики Roux-en-Y в современной абдоминальной хирургии.</p></abstract><trans-abstract xml:lang="en"><p>Objective. Currently, Roux-en-Y reconstruction is a standard surgical technique, and in some cases — the method of choice, for distal resection of the stomach and gastrectomy, for repeated operations on the upper section of the digestive tube and the formation of bilio-digestive anastomoses, for various options for resection of the pancreas, in practice metabolic / bariatric surgery. The aim of this study was to demonstrate the possibilities of using Roux-en-Y reconstruction in surgery of malignant neoplasms of the gastropancreatoduodenal region.Material and methods. The authors presented the experience of using the Roux-en-Y principle in oncosurgery of the gastropancreatoduodenal zone during distal gastric resections, total gastrectomies and gastropancreatoduodenal resections. A comparative analysis of the immediate and long-term functional results of 267 surgical interventions with Ru-style reconstruction and 79 operations performed with other reconstruction options was carried out.Results. A fundamentally better patient tolerance of Roux-en-Y reconstruction was established according to the criteria of the course of the immediate postoperative period (intraoperative complications 12.8% vs 44.3%, the number of relaparotomies 3.4 vs 20.4%, postoperative mortality 4.5 vs 11, 3%), as well as the best functional results of Roux-en-Y reconstruction in relation to the occurrence of impaired gastric evacuation, gastric and esophageal reflux in the near and long term.Conclusion. The experience and results of applying the Roux-en-Y concept, demonstrated in this study, are another confirmation of the unique properties of this reconstruction option - pathogenetic validity, technical reproducibility, predictability of immediate and long-term results - and the related demand for Roux-en-Y reconstruction in abdominal surgery.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>реконструкция по Ру</kwd><kwd>Roux-en-Y</kwd><kwd>гастрэктомия</kwd><kwd>резекция желудка</kwd><kwd>гастропанкреатодуоденальная резекция</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Roux C. Chirurgie gastro-intestinale. Revue de Chirurgie, 1893, No. 13, рр. 402–403.</mixed-citation><mixed-citation xml:lang="en">Roux C. Chirurgie gastro-intestinale. 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