mossjМосковский хирургический журналMoscow Surgical Journal2072-3180ООО «ПРОФИЛЬ – 2С»10.17238/issn2072-3180.2020.4.95-100mossj-435Research ArticleКЛИНИЧЕСКИЕ СЛУЧАИCLINICAL CASEA MULTIDISCIPLINARY APPROACH TO THE TREATMENT OF MALIGNANT HEART TUMORA MULTIDISCIPLINARY APPROACH TO THE TREATMENT OF MALIGNANT HEART TUMORhttps://orcid.org/0000-0003-4204-8865ShumakovD. V.ShumakovD. V.

Shumakov Dmitry Valerievich — MD, professor, corresponding member RAS, Head of the Department of Cardiac and Vascular Surgery

Schepkina str., 61/2, Moscow, 129110

sdvtranspl@rambler.ruhttps://orcid.org/0000-0002-9974-6309DudakovV. A.DudakovV. A.

Dudakov Vladimir Alexandrovich — PhD in Medicine, Head of Department of the Cardiac Surgery

Schepkina str., 61/2, Moscow, 129110

duda-koffmed@mail.ruhttps://orcid.org/0000-0001-7087-5441ZybinD. I.ZybinD. I.

Zybin Dmitry Igorevich – PhD in Medicine, Head of Department of the Cardiac Surgery

Schepkina str., 61/2, Moscow, 129110

poison1983@inbox.ruhttps://orcid.org/0000-0002-0488-0784VashchenkoA. V.VashchenkoA. V.

Vashchenko Anton Vasilievich – PhD in Medicine, Head of Department of the Angiography

Schepkina str., 61/2, Moscow, 129110

anvashchenko@yandex.ruhttps://orcid.org/0000-0003-2338-2120GegenavaB. B.GegenavaB. B.

Gegenava Boris Borisovich – PhD in Medicine, Leading researcher, Head of Department of the Endovascular Surgery

Schepkina str., 61/2, Moscow, 129110

gegenava_boris@dr.comhttps://orcid.org/0000-0002-5194-6379TereshinaA. A.TereshinaA. A.

Tereshina Anna Alexandrovna — Anesthesiologist of the Department of Anesthesiology and Resuscitation

Schepkina str., 61/2, Moscow, 129110

annamedan@icloud.comhttps://orcid.org/0000-0001-6789-9143IvashkinB. V.IvashkinB. V.

Ivashkin Bogdan Vasilievich — Endovascular surgeon of the Department of Angiography

Schepkina str., 61/2, Moscow, 129110

ivashkinbv@mail.ruhttps://orcid.org/0000-0001-6820-1536KurnosovS. A.KurnosovS. A.

Kurnosov Sergey Alekseevich — Junior Researcher of the Department of Endovascular Surgery

Schepkina str., 61/2, Moscow, 129110

sergey.kurnosov.88@mail.ruhttps://orcid.org/0000-0002-2382-8682KapranovM. S.KapranovM. S.

Kapranov Maxim Sergeevich — Researcher of the Department of Endovascular Surgery

Schepkina str., 61/2, Moscow, 129110

kapranovm@mail.ruhttps://orcid.org/0000-0002-0316-8410PopovP. A.PopovM. A.

Popov Mikhail Alexandrovich — Researcher of the Department of Cardiac Surgery

Schepkina str., 61/2, Moscow, 129110

popovcardio88@mail.ruMONIKI named after M.F. VladimirskiiRussian Federation2020090320210495100Copyright © Shumakov D.V., Dudakov V.A., Zybin D.I., Vashchenko A.V., Gegenava B.B., Tereshina A.A., Ivashkin B.V., Kurnosov S.A., Kapranov M.S., Popov P.A., 20212021Shumakov D.V., Dudakov V.A., Zybin D.I., Vashchenko A.V., Gegenava B.B., Tereshina A.A., Ivashkin B.V., Kurnosov S.A., Kapranov M.S., Popov P.A.Shumakov D.V., Dudakov V.A., Zybin D.I., Vashchenko A.V., Gegenava B.B., Tereshina A.A., Ivashkin B.V., Kurnosov S.A., Kapranov M.S., Popov M.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.mossj.ru/jour/article/view/435

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Introduction: paragangliomas are rare neuroendocrine neoplasms with a frequency of 0.001–0.01% in population, which arise from the adrenal medulla and extrarenal autonomic paraganglia, respectively. Paragangliomas of the heart are extremely rare primary neuroendocrine tumors of the heart, accounting for less than 1% of all cardiac neoplasms. Their location is clinically important as they can interfere with heart function. For large paragangliomas of the heart with myocardial invasion, the need for heart reconstruction or transplantation may potentially arise.Discussion: in our case, taking into account the secretion of catecholamines, sick sinus syndrome, a high risk of bleeding, and tumor fragmentation, the first stage was to achieve the regression of the tumor by means of embolization of heart tumor suppliying afferent with coils. However, due to several sources of blood supply of newgrowth, this method of treatment did not lead to the desired effect. In this regard, the tactics of open surgical intervention was chosen to remove the newgrowth with the reconstruction of heart chambers. According to the data of postoperative biopsy, removed tumor was paraganglioma. Conclusion: this experience shows the importance of a multidisciplinary and personalized approach in treatment of patients in a multidisciplinary hospital.

paraganglioma of the heartmalignant tumor of the heartendovascular surgeryembolization of a heart tumorcardiac surgeryReferencesAlakeel F., Al Sannaa G., Ibarra-Cortez S.H., Reardon M.J., Czerniak B., Chan E.Y., Ro J. Cardiac paragangliomas: A case series with clinic pathologic features and succinate dehydrogenase B immunostaining. Annals of Diagnostic Pathology, 2020, No. 45, р. 151477. https://doi.org/10.1016/j.anndiagpath.2020.151477Alakeel F., Al Sannaa G., Ibarra-Cortez S.H., Reardon M.J., Czerniak B., Chan E.Y., Ro J. Cardiac paragangliomas: A case series with clinic pathologic features and succinate dehydrogenase B immunostaining. Annals of Diagnostic Pathology, 2020, No. 45, р. 151477. https://doi.org/10.1016/j.anndiagpath.2020.151477Alam A., Dib E., Hall S., Gonzales G., Guerrero-Miranda C. Heart failure resulting from highly invasive primary cardiac paraganglioma. JACC, 2020, March, No. 24, Vol. 75, р. 11.Alam A., Dib E., Hall S., Gonzales G., Guerrero-Miranda C. Heart failure resulting from highly invasive primary cardiac paraganglioma. JACC, 2020, March, No. 24, Vol. 75, р. 11.Wcislak S.M., King W.S., Waller B.R., Goins N., Dickson P.V. Multifocal pheochromocytoma-paraganglioma in a 29-year-old woman with cyanotic congenital heart disease. Surgery, 2019, No. 16, 165(1), рр. 228–231. https://doi.org/10.1016/j.surg.2018.08.033Wcislak S.M., King W.S., Waller B.R., Goins N., Dickson P.V. Multifocal pheochromocytoma-paraganglioma in a 29-year-old woman with cyanotic congenital heart disease. Surgery, 2019, No. 16, 165(1), рр. 228–231. https://doi.org/10.1016/j.surg.2018.08.033Chang S.H., Yapar I., Kozower B.D. Aorticopulmonary paraganglioma with symptomatic postoperative bradycardia. The Annals of Thoracic Surgery, 2020, May, No. 109, Issue 5, рр. 367–369. https://doi.org/10.1016/j.athoracsur.2019.08.046Chang S.H., Yapar I., Kozower B.D. Aorticopulmonary paraganglioma with symptomatic postoperative bradycardia. The Annals of Thoracic Surgery, 2020, May, No. 109, Issue 5, рр. 367–369. https://doi.org/10.1016/j.athoracsur.2019.08.046Berona K., Joshi R., Woo Y.J., Shrager J. Postpartum diagnosis of cardiac paraganglioma: a case report. The Journal of Emergency Medicine, 2018, October, No. 55, Issue 4, рр. 101–105. https://doi.org/10.1016/j.jemermed.2018.05.034Berona K., Joshi R., Woo Y.J., Shrager J. Postpartum diagnosis of cardiac paraganglioma: a case report. The Journal of Emergency Medicine, 2018, October, No. 55, Issue 4, рр. 101–105. https://doi.org/10.1016/j.jemermed.2018.05.034

The authors declare that there are no conflicts of interest present.