<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">mossj</journal-id><journal-title-group><journal-title xml:lang="ru">Московский хирургический журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Moscow Surgical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2072-3180</issn><publisher><publisher-name>ООО «ПРОФИЛЬ – 2С»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.17238/2072-3180-2025-4-215-221</article-id><article-id custom-type="elpub" pub-id-type="custom">mossj-1106</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ЛИТЕРАТУРНЫЕ ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>LITERARY REVIEWS</subject></subj-group></article-categories><title-group><article-title>Оценка фиброзно-склеротических изменений в щитовидной железе с позиции хирурга. Часть 2</article-title><trans-title-group xml:lang="en"><trans-title>The surgeon’s estimation of fibrosis-sclerotic alteration in the thyroid. Part 2</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3844-1632</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Семиков</surname><given-names>В. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Semikov</surname><given-names>V. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Семиков Василий Иванович – профессор кафедры факультетской хирургии № 2 им. Г.И. Лукомского, доктор медицинских наук, профессор. </p><p>119047, г. Москва, ул. Трубецкая 8–2</p></bio><bio xml:lang="en"><p>Semikov Vasily Ivanovich – Professor of the Department of Faculty Surgery № 2 named after G.I. Lukomski, MD, Professor.</p><p>Trubetskaya str., 8–2, Moscow, 119047</p></bio><email xlink:type="simple">Semik61@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7581-1543</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Александров</surname><given-names>Ю. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Aleksandrov</surname><given-names>Y. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Александров Юрий Константинович – профессор кафедры хирургических болезней с курсом эндокринной хирургии им. Н.П. Пампутиса, доктор медицинских наук, профессор.</p><p>150000, г. Ярославль, ул. Революционная, д. 5</p></bio><bio xml:lang="en"><p>Aleksandrov Yuri Konstantinovich – Professor of the Department of Surgical Diseases with a course in endocrine Surgery named after N.P. Pamputis, MD, Professor.</p><p>Revolutsionnaya str., 5, Yaroslavl, 150000</p></bio><email xlink:type="simple">yka2000@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8001-1601</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шулутко</surname><given-names>А. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Shulutko</surname><given-names>A. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Шулутко Александр Михайлович – профессор кафедры факультетской хирургии № 2 им. Г.И. Лукомского, доктор медицинских наук, профессор.</p><p>119047, г. Москва, ул. Трубецкая 8–2</p></bio><bio xml:lang="en"><p>Shulutko Alexandr Mikhailovich – Professor of the Department of Faculty Surgery No 2 named after G.I. Lukomski, MD, Professor.</p><p>Trubetskaya str., 8–2, Moscow, 119047</p></bio><email xlink:type="simple">Shulutko@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7838-3054</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Боблак</surname><given-names>Ю. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Boblak</surname><given-names>J. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Боблак Юлия Александровна – ассистент кафедры факультетской хирургии № 2 им. Г.И. Лукомского.</p><p>119047, г. Москва, ул. Трубецкая 8–2</p></bio><bio xml:lang="en"><p>Boblak Julia Alexandrovna – Assistant of the Department of Faculty Surgery № 2 named after G.I. Lukomsky.</p><p>119047, Moscow, st. Trubetskaya 8–2.</p></bio><email xlink:type="simple">Julia.boblak@icloud.com</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГАОУ ВО Первый Московский государственный медицинский университет им. И.М. Сеченова Министерства здравоохранения Российской Федерации (Сеченовский университет)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal State Autonomous Educational Institution of Higher Education Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University)</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБОУ ВО Ярославский государственный медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal State Budgetary Educational Institution of Higher Education Yaroslavl State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>15</day><month>12</month><year>2025</year></pub-date><volume>0</volume><issue>4</issue><fpage>215</fpage><lpage>221</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Семиков В.И., Александров Ю.К., Шулутко А.М., Боблак Ю.А., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Семиков В.И., Александров Ю.К., Шулутко А.М., Боблак Ю.А.</copyright-holder><copyright-holder xml:lang="en">Semikov V.I., Aleksandrov Y.K., Shulutko A.M., Boblak J.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.mossj.ru/jour/article/view/1106">https://www.mossj.ru/jour/article/view/1106</self-uri><abstract><p>Введение. Фиброзно-склеротические изменения в узловых образованиях щитовидной железы часто являются следствием диагностических и диапевтических манипуляций, влияющих на структуру и морфологию узлов. Оценка изменений неоднозначна и зависит, как от временного фактора, так и изначальной структуры образования. Уменьшение размеров и объема кист, узлов и опухолей щитовидной железы в результате применения различных диагностических манипуляций являются следствием индуцированного прогрессирующего фиброза и склероза, которые влияют на оценку, течение и исход патологического процесса. Цель. Оценить по литературным данным варианты и исходы фиброзно-склеротических изменений в образованиях щитовидной железы после диагностических и диапевтических манипуляций. Методы. Поиск литературных источников в базах данных E-library, PubMed, Scopus по ключевым словам «фиброз», «склероз», «кальциноз», «гиалиноз», «пункция» в связке со словосочетанием «щитовидная железа». Результаты. Применение различных пункционных методов диагностики, позволяющих получить материал для достоверной морфологической оценки процессов, происходящих в щитовидной железе, сегодня безоговорочно признано научным сообществом мира. В ряде случаев помимо диагностики пункции оказывают лечебное (диапевтическое) воздействие, направленное на уменьшение или полное устранение патологического очага в органе. Забор клеточного материала без аспирации, а особенно с аспирацией, всегда сопровождается повреждением как нормальной ткани, так и патологических очагов щитовидной железы с развитием альтеративных и склеротических процессов различной степени выраженности. Изменения могут быть не только минимальными, но и значительными, приводящими к грубым структурным изменениям иногда с полным замещением первичной морфологической структуры очагового образования ЩЖ фиброзом. После выполнения диапевтических манипуляций формирование фиброза и склероза является ожидаемым, прогнозируемым, лечебным результатом. Заключение. Сегодня пункционные методы при узловых образованиях щитовидной железы являются основными компонентами диагностики и выбора тактики лечения. Однако в ряде случаев, после ранее выполненных неоднократных пункций и диапевтических вмешательств, получение информативного материала для цитологического исследования представляет трудности. Фиброз, гиалиноз и склероз, возникающие в ткани и узловых образованиях щитовидной железы в различные сроки после диагностических и диапевтических манипуляций, могут существенно влиять как на верификацию характера заболевания, так и выбор лечебной тактики.</p></abstract><trans-abstract xml:lang="en"><p>Introduction. Fibrosclerotic changes in thyroid nodules are often the result of diagnostic and therapeutic manipulations that affect the structure and morphology of the nodes. The assessment of changes is ambiguous and depends on both the time factor and the initial structure of education. A decrease in the size and volume of cysts, nodules and tumors of the thyroid gland as a result of various diagnostic manipulations is a consequence of induced progressive fibrosis and sclerosis, which affect the assessment, course and outcome of the pathological process. The purpose of the study. To evaluate the variants and outcomes of fibrosclerotic changes in thyroid formations after diagnostic and therapeutic manipulations based on literature data. Methods. Search for literary sources in the databases E-library, PubMed, Scopus for the keywords "fibrosis", "sclerosis", "calcification", "hyalinosis", "puncture" in conjunction with the phrase "thyroid gland". Treatment results. The use of various puncture diagnostic methods, which allow obtaining material for a reliable morphological assessment of the processes occurring in the thyroid gland, is now unconditionally recognized by the scientific community of the world. In some cases, in addition to diagnosis, punctures have a therapeutic (diapeutic) effect aimed at reducing or completely eliminating the pathological focus in the organ. The removal of cellular material without aspiration, and especially with aspiration, is always accompanied by damage to both normal tissue and pathological foci of the thyroid gland with the development of alterative and sclerotic processes of varying severity. The changes can be not only minimal, but also significant, leading to gross structural changes, sometimes with complete replacement of the primary morphological structure of thyroid nodule formation by fibrosis. After performing diapeutic manipulations, the formation of fibrosis and sclerosis is an expected, predictable, therapeutic result. Conclusion. Today, puncture methods for thyroid nodules are the main components of diagnosis and choice of treatment tactics. However, in some cases, after previously performed repeated punctures and diapeutic interventions, it is difficult to obtain informative material for cytological examination. Fibrosis, hyalinosis and sclerosis that occur in the tissue and nodules of the thyroid gland at various times after diagnostic and therapeutic manipulations can significantly affect both the verification of the nature of the disease and the choice of therapeutic tactics.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>щитовидная железа</kwd><kwd>пункционная биопсия</kwd><kwd>диапевтика</kwd><kwd>фиброз</kwd><kwd>склероз</kwd></kwd-group><kwd-group xml:lang="en"><kwd>thyroid gland</kwd><kwd>fine needle aspiration biopsy</kwd><kwd>diapeutics</kwd><kwd>fibrosis</kwd><kwd>sclerosis</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Семиков В.И., Александров Ю.К., Шулутко А.М., Боблак Ю.А. Оценка фиброзно-склеротических изменений в щитовидной железе с позиции хирурга. Часть 1. Московский хирургический журнал, 2025. № 2. C. 192–199. https://doi.org/10.17238/2072-3180-2025-2-192-199</mixed-citation><mixed-citation xml:lang="en">Semikov V.I., Aleksandrov Y.K., Shulutko A.M., Boblak J.A. The surgeon’s estimation of fibrosis-sclerotic alteration in the thyroid. Part 1. Moscow Surgical Journal, 2025, № 2, рp. 192–199. (In Russ.) https://doi.org/10.17238/2072-3180-2025-2-192-199.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Uppal N., Collins R., James B. Thyroid nodules: Global, economic, and personal burdens. Front Endocrinol (Lausanne), 2023. № 14, рр. 1113977. https://doi.org/10.3389/fendo.2023.1113977</mixed-citation><mixed-citation xml:lang="en">Uppal N., Collins R., James B. Thyroid nodules: Global, economic, and personal burdens. Front Endocrinol (Lausanne), 2023, № 14:1113977. https://doi.org/10.3389/fendo.2023.1113977</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Дзодзаева А.В., Бондаренко Е.В., Терехова М.А., Ванушко А.В., Ванушко В.Э., Трошина Е.А. Современное представление о диагностике, лечении и предикторах прогрессии папиллярной микрокарциномы щитовидной железы. Клиническая и экспериментальная тиреоидология, 2024. № 20(3). С. 14–20. https://doi.org/10.14341/ket12813</mixed-citation><mixed-citation xml:lang="en">Dzodzaeva A.V., Bondarenko E.V., Terekhova M.A., Vanushko A.V., Vanushko V.E., Troshina E.A. Current understanding of diagnosis, treatment and predictors of papillary thyroid microcarcinoma progression. Clinical and experimental thyroidology, 2024, № 20(3), рр. 14–20. (In Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Wang C.C., Friedman L., Kennedy G.C., et al. A large multicenter correlation study of thyroid nodule cytopathology and histopathology. Thyroid. 2011. № 21. pр. 243–251</mixed-citation><mixed-citation xml:lang="en">Wang C.C., Friedman L., Kennedy G.C., et al. A large multicenter correlation study of thyroid nodule cytopathology and histopathology. Thyroid, 2011, № 21, pр. 243–251.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Edens J., Chand M., Asghar I., Bhatt M., Anderson I., Miller S. Practical diagnostic utility of thyroid fine-needle aspiration cell blocks: is always too much? J Am Soc Cytopathol., 2021, № 10(2), pp. 164 – 167. https://doi.org/10.1016/j.jasc.2020.07.136.</mixed-citation><mixed-citation xml:lang="en">Edens J., Chand M., Asghar I., Bhatt M., Anderson I., Miller S. Practical diagnostic utility of thyroid fine-needle aspiration cell blocks: is always too much? J Am Soc Cytopathol., 2021, № 10(2). pp. 164–167. https://doi.org/10.1016/j.jasc.2020.07.136</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Smith T., Kaufman C.S. Ultrasound Guided Thyroid Biopsy. Tech Vasc Interv Radiol., 2021, № 24(3), рр. 100768. https://doi.org/10.1016/j.tvir.2021.100768</mixed-citation><mixed-citation xml:lang="en">Smith T., Kaufman C.S. Ultrasound Guided Thyroid Biopsy. Tech Vasc Interv Radiol., 2021, № 24(3), рр. 100768. https://doi.org/10.1016/j.tvir.2021.100768</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Jones J.D., Pittman D.L., Sanders L.R. Necrosis of thyroid nodules after fine needle aspiration. Acta Cytol., 1985, № 29(1), рр. 29–32.</mixed-citation><mixed-citation xml:lang="en">Jones J.D., Pittman D.L., Sanders L.R. Necrosis of thyroid nodules after fine needle aspiration. Acta Cytol., 1985, № 29(1), рр. 29–32.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Layfield L.J., Lones M.A. Necrosis in thyroid nodules after fine needle aspiration biopsy. Report of two cases. Acta Cytol., 1991, № 35(4), рр. 427–430.</mixed-citation><mixed-citation xml:lang="en">Layfield L.J., Lones M.A. Necrosis in thyroid nodules after fine needle aspiration biopsy. Report of two cases. Acta Cytol., 1991, № 35(4), рр. 427–430.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">LiVolsi V.A., Merino M.J. Worrisome histologic alterations following fine-needle aspiration of the thyroid (WHAFFT). Pathology annual, 1994, № 29 (2), рр. 99–120.</mixed-citation><mixed-citation xml:lang="en">LiVolsi V.A., Merino M.J. Worrisome histologic alterations following fine-needle aspiration of the thyroid (WHAFFT). Pathology annual, 1994, № 29 (2), рр. 99–120.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Pandit A.A., Vaideeswar P., Mohite J.D. Infarction of a thyroid nodule after fine needle aspiration biopsy. Acta Cytol., 1998, № 42(5), рр.1307–1309.</mixed-citation><mixed-citation xml:lang="en">Pandit A.A., Vaideeswar P., Mohite J.D. Infarction of a thyroid nodule after fine needle aspiration biopsy. Acta Cytol., 1998, № 42(5), рр.1307–1309.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Gordon D.L., Flisak M., Fisher S.G. Changes in thyroid nodule volume caused by fine-needle aspiration: a factor complicating the interpretation of the effect of thyrotropin suppression on nodule size. J Clin Endocrinol Metab., 1999, № 84(12), рр. 4566–4569. https://doi.org/10.1210/jcem.84.12.6195</mixed-citation><mixed-citation xml:lang="en">Gordon D.L., Flisak M., Fisher S.G. Changes in thyroid nodule volume caused by fine-needle aspiration: a factor complicating the interpretation of the effect of thyrotropin suppression on nodule size. J Clin Endocrinol Metab., 1999, № 84(12), рр. 4566–4569. https://doi.org/10.1210/jcem.84.12.6195</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Rajasekhar A., Sundaram C., Chowdhary T., Charanpal M., Ratnakar K.S. Diagnostic utility of fine-needle sampling without aspiration: a prospective study. Diagn Cytopathol., 1991, № 7(5), рр. 473–476. https://doi.org/10.1002/dc.2840070507</mixed-citation><mixed-citation xml:lang="en">Rajasekhar A., Sundaram C., Chowdhary T., Charanpal M., Ratnakar K.S. Diagnostic utility of fine-needle sampling without aspiration: a prospective study. Diagn Cytopathol., 1991, № 7(5), рр. 473–476. https://doi.org/10.1002/dc.2840070507</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Degirmenci B., Haktanir A., Albayrak R., Acar M., Sahin D.A., Sahin O., Yucel A., Caliskan G. Sonographically guided fine-needle biopsy of thyroid nodules: the effects of nodule characteristics, sampling technique, and needle size on the adequacy of cytological material. Clin Radiol., 2007, № 62(8), рр. 98–803. https://doi.org/10.1016/j.crad.2007.01.024</mixed-citation><mixed-citation xml:lang="en">Degirmenci B., Haktanir A., Albayrak R., Acar M., Sahin D.A., Sahin O., Yucel A., Caliskan G. Sonographically guided fine-needle biopsy of thyroid nodules: the effects of nodule characteristics, sampling technique, and needle size on the adequacy of cytological material. Clin Radiol., 2007, № 62(8), рр. 98–803. https://doi.org/10.1016/j.crad.2007.01.024</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Shumrick C.M., Simmonds J.C., Ogden L.L., Snowden C.A., Dhingra J.K. A Blinded Randomized Trial Comparing 2 Needle Gauges for Fine-Needle Biopsy of Thyroid Nodules. OTO Open., 2021, vol. 10, № 5(2), pp. 2473974X211013732. https://doi.org/10.1177/2473974X211013732</mixed-citation><mixed-citation xml:lang="en">Shumrick C.M., Simmonds J.C., Ogden L.L., Snowden C.A., Dhingra J.K. A Blinded Randomized Trial Comparing 2 Needle Gauges for Fine-Needle Biopsy of Thyroid Nodules. OTO Open., 2021, vol. 10, № 5(2), pp. 2473974X211013732. https://doi.org/10.1177/2473974X211013732</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Долидзе Д.Д., Чеченин Г.М., Кованцев С.Д., Багателия З.А., Варданян А.В., Ротин Д.Л., Слепухова Д.В. Диагностическая ценность трепан-биопсии фолликулярных опухолей щитовидной железы. Эндокринология: новости, мнения, обучение, 2023. № 12(1). C. 48–55. https://doi.org/10.33029/2304-9529-2023-12-1-48-55</mixed-citation><mixed-citation xml:lang="en">Dolidze D.D., Chechenin G.M., Kovantsev S.D., Bagatelia Z.A., Vardanyan A.V., Rotin D.L., Slepukhova D.V. Diagnostic value of trepan biopsy of follicular thyroid tumors. Endocrinology: news, opinions, training, 2023, № 12(1), рр. 48–55. (In Russ.) https://doi.org/10.33029/2304-9529-2023-12-1-48-55</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Jung C.K., Baek J.H., Na D.G., Oh Y.L., Yi K.H., Kang H.C. 2019 Practice guidelines for thyroid core needle biopsy: A report of the Clinical Practice Guidelines Development Committee of the Korean Thyroid Association. J Pathol Transl Med., 2020, vol. 54, № 1, рр. 64–86.</mixed-citation><mixed-citation xml:lang="en">Jung C.K., Baek J.H., Na D.G., Oh Y.L., Yi K.H., Kang H.C. 2019 Practice guidelines for thyroid core needle biopsy: A report of the Clinical Practice Guidelines Development Committee of the Korean Thyroid Association. J Pathol Transl Med., 2020., vol. 54, № 1, рр. 64–86.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Шапиро Н.А., Богин Ю.Н., Бондаренко В.О., Орлов В.М. Возможность цитологического исследования при комплексной экспесс-диагностике заболеваний щитовидной железы. Методические рекомендации, 1992.</mixed-citation><mixed-citation xml:lang="en">Shapiro N.A., Bogin Yu.N., Bondarenko V.O., Orlov V.M. The possibility of cytological examination in the complex rapid diagnosis of thyroid diseases. Methodological recommendations, 1992. (In Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Бубнов А.Н., Кузмичев А.С., Гринева Е.Н., Трунин Е.М. Узловой зоб. Диагностика и методы лечения. 1997.</mixed-citation><mixed-citation xml:lang="en">Bubnov A.N., Kuzmichev A.S., Grineva E.N., Trunin E.M. Nodular goiter. Diagnosis and treatment methods, 1997. (In Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Майор Н.Н., Цодикова Л.Б. Пункционная цитологическая диагностика щитовидной железы: возможности и ограничение метода. Архив патологии, 1996. № 2(58). С. 74–78.</mixed-citation><mixed-citation xml:lang="en">Major N.N., Tsodikova L.B. Puncture cytological diagnosis of the thyroid gland: possibilities and limitations of the method. Pathology archive.1996. № 2(58). рр. 74 – 78. (In Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Jose M.T., Hunt B., Magill S.B. Vanishing papillary thyroid carcinoma: morphological changes after fine-needle aspiration. AACE Clin Case Rep., 2019, № 5(5), рр. 298–301. https://doi.org/10.4158/ACCR2018-0575</mixed-citation><mixed-citation xml:lang="en">Jose M.T., Hunt B., Magill S.B. Vanishing papillary thyroid carcinoma: morphological changes after fine-needle aspiration. AACE Clin Case Rep., 2019, № 5(5), рр. 298–301. https://doi.org/10.4158/ACCR2018-0575</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Bhatia P., Deniwar A., Mohamed H.E., Sholl A., Murad F., Aslam R., Kandil E. Vanishing tumors of thyroid: histological variations after fine needle aspiration. Gland Surg., 2016, № 5(3), рр. 270–277. https://doi.org/10.21037/gs.2016.01.05</mixed-citation><mixed-citation xml:lang="en">Bhatia P., Deniwar A., Mohamed H.E., Sholl A., Murad F., Aslam R., Kandil E. Vanishing tumors of thyroid: histological variations after fine needle aspiration. Gland Surg., 2016, № 5(3), рр. 270–277. https://doi.org/10.21037/gs.2016.01.05</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Eze O.P., Cai G., Baloch Z.W., Khan A., Virk R., Hammers L.W., Udelsman R., Roman S.A., Sosa J.A., Carling T., Chhieng D., Theoharis C.G., Prasad M.L. Vanishing thyroid tumors: a diagnostic dilemma after ultrasonography-guided fine-needle aspiration. Thyroid., 2013, № 23(2), рр. 194–200. https://doi.org/10.1089/thy.2012.0157</mixed-citation><mixed-citation xml:lang="en">Eze O.P., Cai G., Baloch Z.W., Khan A., Virk R., Hammers L.W., Udelsman R., Roman S.A., Sosa J.A., Carling T., Chhieng D., Theoharis C.G., Prasad M.L. Vanishing thyroid tumors: a diagnostic dilemma after ultrasonography-guided fine-needle aspiration. Thyroid., 2013, № 23(2), рр. 194–200. https://doi.org/10.1089/thy.2012.0157</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Brito J.P., Yarur A.J., Prokop L.J., et al. Prevalence of thyroid cancer in multinodular goiter versus single nodule: a systematic review and meta-analysis. Thyroid, 2013, № 23(4), рр. 449–455. https://doi.org/10.1089/thy.2012.0156</mixed-citation><mixed-citation xml:lang="en">Brito J.P., Yarur A.J., Prokop L.J., et al. Prevalence of thyroid cancer in multinodular goiter versus single nodule: a systematic review and meta-analysis. Thyroid, 2013, № 23(4), рр. 449–455. https://doi.org/10.1089/thy.2012.0156</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Liu Y.F., Ahmed S., Bhuta S., Sercarz J.A. Infarction of papillary thyroid carcinoma after fine-needle aspiration: case series and review of literature. JAMA Otolaryngol Head Neck Surg., 2014, № 140(1), рр. 52–57. https://doi.org/10.1001/jamaoto.2013.5650. PMID: 24232180</mixed-citation><mixed-citation xml:lang="en">Liu Y.F., Ahmed S., Bhuta S., Sercarz J.A. Infarction of papillary thyroid carcinoma after fine-needle aspiration: case series and review of literature. JAMA Otolaryngol Head Neck Surg., 2014, № 140(1), рр. 52–57. https://doi.org/10.1001/jamaoto.2013.5650</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Baloch Z.W., LiVolsi V.A. Post fine-needle aspiration histologic alterations of thyroidrevisited. AmJClinPathol., 1999, № 112(3), рр. 311–316. https://doi.org/10.1093/ajcp/112.3.111</mixed-citation><mixed-citation xml:lang="en">Baloch Z.W., LiVolsi V.A. Post fine-needle aspiration histologic alterations of thyroidrevisited. AmJClinPathol., 1999, № 112(3), рр. 311–316. https://doi.org//10.1093/ajcp/112.3.111</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Murad F., Aslam R., Kandil E. Vanishing tumors of thyroid: histological variations after fine needle aspiration. Gland Surg., 2016, № 5(3), рр. 270–277. https://doi.org/10.21037/gs.2016.01.05</mixed-citation><mixed-citation xml:lang="en">Murad F., Aslam R., Kandil E. Vanishing tumors of thyroid: histological variations after fine needle aspiration. Gland Surg., 2016, № 5(3), рр. 270–277. https://doi.org/10.21037/gs.2016.01.05</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Bolat F., Kayaselcuk F., Nursal T.Z., Reyhan M., Bal N., Yildirim S., Tuncer I. Histopathological changes in thyroid tissue after fine needle aspiration biopsy. Pathol Res Pract., 2007, № 203(9), рр. 641–645. https://doi.org/10.1016/j.prp.2007.05.004</mixed-citation><mixed-citation xml:lang="en">Bolat F., Kayaselcuk F., Nursal T.Z., Reyhan M., Bal N., Yildirim S., Tuncer I. Histopathological changes in thyroid tissue after fine needle aspiration biopsy. Pathol Res Pract., 2007, № 203(9), рр. 641–645. https://doi.org/10.1016/j.prp.2007.05.004</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Moon W.S., Kang M.J., Youn H.J. Diagnostic pitfall of thyroid fine-needle aspiration induced fibrosis: follicular adenoma mimicking medullary thyroid carcinoma in frozen section. Diagnostic pathology, 2021, № 16(1), рр. 25. https://doi.org/10.1186/s13000-021-01087-2</mixed-citation><mixed-citation xml:lang="en">Moon W.S., Kang M.J., Youn H.J. Diagnostic pitfall of thyroid fine-needle aspiration induced fibrosis: follicular adenoma mimicking medullary thyroid carcinoma in frozen section.  Diagnostic pathology, 2021, № 16(1), рр. 25.  https://doi.org/10.1186/s13000-021-01087-2</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Семкина Г.В., Абросимов А.Ю., Абдулхабирова Ф.М., Ванушко В.Э. Оценка результатов повторных таб у пациентов с узловым коллоидным зобом (анализ собственных данных и обзор литературы). Клиническая и экспериментальная тиреоидология, 2014. № 10(2). С. 32–37.</mixed-citation><mixed-citation xml:lang="en">Semkina G.V., Abrosimov A.Yu., Abdulkhabirova F.M., Vanushko V.E. Evaluation of the results of repeated TAB in patients with nodular colloidal goiter (analysis of own data and literature review). Clinical and experimental thyroidology, 2014, № 10(2), рр. 32–37. (In Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Horvath E., Majlis S. An ultrasonogram reporting system for thyroid nodules stratifying cancer risk for clinical management. J Clin Endocrinol Metab., 2009, № 94 (5), рр. 1748–1751.</mixed-citation><mixed-citation xml:lang="en">Horvath E., Majlis S. An ultrasonogram reporting system for thyroid nodules stratifying cancer risk for clinical management. J Clin Endocrinol Metab., 2009, № 94(5), рр. 1748–1751.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
